{"title":"Flexible Electronic Patch Utilizing Gelatin Film for Heart and Brain Signal Detection","authors":"He Tao, Ximin Yuan, Debin Shan, Bin Guo, Jie Xu","doi":"10.1021/acs.langmuir.4c03834","DOIUrl":null,"url":null,"abstract":"Flexible electronic patches have been widely studied in various fields. However, they still face serious challenges in cardio-brain signaling monitoring to achieve accurate adhesion and detection with compatibility in mildly humid environments. To tackle these challenges, we engineered a gelatin hydrogel film cross-linked with a biocompatible matrix factor and combined it with a blend of liquid metal and PVP to create the flexible electronic patch. The flexible patch has good biocompatibility and fatigue resistance due to the incorporation of liquid metal and natural gelatin, with the conductivity of liquid metal and minimal toxicity of the gelatin film. It is possible to securely insert it into the body for a duration of 3 weeks while maintaining monitoring functionality and withstanding 10 000 cycles of flexural fatigue. This research provides an innovative approach to the future advancement of flexible electronic patches.","PeriodicalId":50,"journal":{"name":"Langmuir","volume":"37 1","pages":""},"PeriodicalIF":3.9000,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Langmuir","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1021/acs.langmuir.4c03834","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Flexible electronic patches have been widely studied in various fields. However, they still face serious challenges in cardio-brain signaling monitoring to achieve accurate adhesion and detection with compatibility in mildly humid environments. To tackle these challenges, we engineered a gelatin hydrogel film cross-linked with a biocompatible matrix factor and combined it with a blend of liquid metal and PVP to create the flexible electronic patch. The flexible patch has good biocompatibility and fatigue resistance due to the incorporation of liquid metal and natural gelatin, with the conductivity of liquid metal and minimal toxicity of the gelatin film. It is possible to securely insert it into the body for a duration of 3 weeks while maintaining monitoring functionality and withstanding 10 000 cycles of flexural fatigue. This research provides an innovative approach to the future advancement of flexible electronic patches.
期刊介绍：
Langmuir is an interdisciplinary journal publishing articles in the following subject categories:
Colloids: surfactants and self-assembly, dispersions, emulsions, foams
Interfaces: adsorption, reactions, films, forces
Biological Interfaces: biocolloids, biomolecular and biomimetic materials
Materials: nano- and mesostructured materials, polymers, gels, liquid crystals
Electrochemistry: interfacial charge transfer, charge transport, electrocatalysis, electrokinetic phenomena, bioelectrochemistry
Devices and Applications: sensors, fluidics, patterning, catalysis, photonic crystals
However, when high-impact, original work is submitted that does not fit within the above categories, decisions to accept or decline such papers will be based on one criteria: What Would Irving Do?
Langmuir ranks #2 in citations out of 136 journals in the category of Physical Chemistry with 113,157 total citations. The journal received an Impact Factor of 4.384*.
This journal is also indexed in the categories of Materials Science (ranked #1) and Multidisciplinary Chemistry (ranked #5).
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