Tomato fruit ripening is modulated by redox modification of RNA demethylase

IF 15.8 1区 生物学 Q1 PLANT SCIENCES Nature Plants Pub Date : 2025-01-10 DOI:10.1038/s41477-024-01900-y
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Abstract

This study reveals that the RNA N6-methyladenosine (m6A) demethylase SlALKBH2 undergoes a reduction–oxidation (redox) modification in which hydrogen peroxide mediates the oxidation and the reductase SlNTRC catalyses the reduction. This redox modification affects SlALKBH2 protein stability, thereby modulating its physiological function in the regulation of normal ripening of tomato fruits.

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番茄果实成熟是由RNA去甲基酶的氧化还原修饰调控的
本研究揭示了RNA n6 -甲基腺苷(m6A)去甲基化酶SlALKBH2经历了还原-氧化(氧化还原)修饰,其中过氧化氢介导氧化,还原酶SlNTRC催化还原。这种氧化还原修饰影响了SlALKBH2蛋白的稳定性,从而调节了其调节番茄果实正常成熟的生理功能。
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来源期刊
Nature Plants
Nature Plants PLANT SCIENCES-
CiteScore
25.30
自引率
2.20%
发文量
196
期刊介绍: Nature Plants is an online-only, monthly journal publishing the best research on plants — from their evolution, development, metabolism and environmental interactions to their societal significance.
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