{"title":"Challenges of reproducible AI in biomedical data science.","authors":"Henry Han","doi":"10.1186/s12920-024-02072-6","DOIUrl":null,"url":null,"abstract":"<p><p>Artificial intelligence (AI) is revolutionizing biomedical data science at an unprecedented pace, transforming various aspects of the field with remarkable speed and depth. However, a critical issue remains unclear: how reproducible are the AI models and systems employed in biomedical data science? In this study, we examine the challenges of AI reproducibility by analyzing the factors influenced by data, model, and learning complexities, as well as through a game-theoretical perspective. While adherence to reproducibility standards is essential for the long-term advancement of AI, the conflict between following these standards and aligning with researchers' personal goals remains a significant hurdle in achieving AI reproducibility.</p>","PeriodicalId":8915,"journal":{"name":"BMC Medical Genomics","volume":"18 Suppl 1","pages":"8"},"PeriodicalIF":2.1000,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11724458/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMC Medical Genomics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s12920-024-02072-6","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"GENETICS & HEREDITY","Score":null,"Total":0}
引用次数: 0
Abstract
Artificial intelligence (AI) is revolutionizing biomedical data science at an unprecedented pace, transforming various aspects of the field with remarkable speed and depth. However, a critical issue remains unclear: how reproducible are the AI models and systems employed in biomedical data science? In this study, we examine the challenges of AI reproducibility by analyzing the factors influenced by data, model, and learning complexities, as well as through a game-theoretical perspective. While adherence to reproducibility standards is essential for the long-term advancement of AI, the conflict between following these standards and aligning with researchers' personal goals remains a significant hurdle in achieving AI reproducibility.
Alison P Galvani, Alyssa S Parpia, Abhishek Pandey, Pratha Sah, Kenneth Colón, Gerald Friedman, Travis Campbell, James G Kahn, Burton H Singer, Meagan C Fitzpatrick
期刊介绍:
BMC Medical Genomics is an open access journal publishing original peer-reviewed research articles in all aspects of functional genomics, genome structure, genome-scale population genetics, epigenomics, proteomics, systems analysis, and pharmacogenomics in relation to human health and disease.