Functional and oncological outcomes of transoral laser versus robotic surgery in supraglottic squamous cell carcinoma

IF 4 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Oral oncology Pub Date : 2025-02-01 DOI:10.1016/j.oraloncology.2025.107178
Charlotte Loubieres , Robin Baudouin , Marta Circiu , Florent Couineau , Lise Crevier-Buchman , Tiffany Rigal , Clémence Forges , Aude Julien-Laferriere , Grégoire Vialatte De Pemille , Jérôme R. Lechien , Stéphane Hans
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引用次数: 0

Abstract

Objective

To compare the surgical, functional and oncological outcomes of Transoral Laser Microsurgery (TLM) and Transoral Robotic Surgery (TORS) for the treatment of supraglottic squamous cell carcinoma.
Study Design:
Retrospective case series with prospective data.
Settings:
Tertiary Academic Medical Center.

Methods

A chart-review analysis, with prospective follow-up was performed on 122 patients treated for a supraglottic squamous cell carcinoma with either TLM or TORS between 2003 and 2019. Patients were grouped according to the surgical technique used. Clinical, surgical, functional and oncological outcomes were compared, including local and regional controls, DFS, and OS, and postoperative complications.

Results

A total of 122 patients, including 47 treated with TLM and 75 with TORS. Negative margins were observed in n = 12/47 (25.5 %) of TLM cases and n = 4/75 (5.3 %) of TORS cases (p < 0.05). There was no significant difference between the two techniques in terms of 5-year local and regional control, however a significant difference was found in disease-free survival and overall survival. The functional laryngeal preservation rate was 97.8 % in the TLM group and 100 % in the TORS group.

Conclusion

Both techniques appear to be safe and effective, though TORS shows superiority in achieving negative margins compared to TLM. Therefore, the choice of technique should be tailored to available resources, surgical team preferences, and experience, while also considering the learning curves associated with each approach.
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经口激光与机器人手术治疗声门上鳞状细胞癌的功能和肿瘤预后。
目的:比较经口激光显微手术(TLM)与经口机器人手术(TORS)治疗声门上鳞癌的手术、功能和肿瘤预后。研究设计:具有前瞻性数据的回顾性病例系列。设置:三级学术医疗中心。方法:对2003年至2019年期间接受TLM或TORS治疗的122例声门上鳞状细胞癌患者进行回顾性分析和前瞻性随访。根据手术方法对患者进行分组。比较临床、手术、功能和肿瘤结果,包括局部和区域对照、DFS和OS以及术后并发症。结果:122例患者,TLM治疗47例,TORS治疗75例。在TLM病例中,n = 12/47(25.5%)和TORS病例中,n = 4/75(5.3%)观察到阴性边缘(p)。结论:两种技术都是安全有效的,尽管TORS在实现阴性边缘方面比TLM更有优势。因此,技术的选择应根据现有的资源、手术团队的偏好和经验进行调整,同时也要考虑与每种入路相关的学习曲线。
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来源期刊
Oral oncology
Oral oncology 医学-牙科与口腔外科
CiteScore
8.70
自引率
10.40%
发文量
505
审稿时长
20 days
期刊介绍: Oral Oncology is an international interdisciplinary journal which publishes high quality original research, clinical trials and review articles, editorials, and commentaries relating to the etiopathogenesis, epidemiology, prevention, clinical features, diagnosis, treatment and management of patients with neoplasms in the head and neck. Oral Oncology is of interest to head and neck surgeons, radiation and medical oncologists, maxillo-facial surgeons, oto-rhino-laryngologists, plastic surgeons, pathologists, scientists, oral medical specialists, special care dentists, dental care professionals, general dental practitioners, public health physicians, palliative care physicians, nurses, radiologists, radiographers, dieticians, occupational therapists, speech and language therapists, nutritionists, clinical and health psychologists and counselors, professionals in end of life care, as well as others interested in these fields.
期刊最新文献
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