Clinical outcomes of reconstruction on tissue defects with thin anterolateral thigh flap versus commonly used free soft flaps: A meta-analysis

IF 2 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2025-01-08 DOI:10.1016/j.jormas.2025.102225

Qiang Xu, Wen Li, Xianglong Zheng, Lisong Lin

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Abstract

Background

The thin anterolateral thigh flap (tALTF) is gaining attention in reconstructive surgery due to its aesthetic and functional advantages. However, its clinical safety and outcomes compared to other commonly used free soft flaps (CUFSFs) remain unclear.

Methods

Studies were systematically searched from PubMed, EMBASE, Medline, Cochrane, Web of Science, and China National Knowledge Infrastructure Database up to November 2, 2024. Flap failure, donor and recipient site morbidity, secondary salvage surgery, and patient satisfaction were evaluated.

Results

A total of 416 cases from 7 studies were included in our analysis. No significant difference was observed between the two groups in flap failure and secondary salvage surgery. However, tALTF showed significant advantages over CUFSFs in skin grafting, donor and recipient site morbidity, and patient satisfaction.

Conclusion

This meta-analysis highlights the clinical safety and superior outcomes of tALTF compared to CUFSFs in reconstructive surgery, suggesting its viability as a preferred option for surgeons. However, the retrospective design of the included studies and limited sample sizes necessitate further large-scale prospective studies to validate these results.

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薄前外侧皮瓣与多个游离软皮瓣重建组织缺损的临床效果荟萃分析。

背景：薄股前外侧皮瓣（tALTF）由于其美观和功能上的优势，在重建外科中越来越受到关注。然而，与其他常用的游离软瓣（cufsf）相比，其临床安全性和结果尚不清楚。方法：系统检索截至2024年11月2日的PubMed、EMBASE、Medline、Cochrane、Web of Science和中国国家知识基础设施数据库。评估皮瓣失败、供受体部位发病率、二次抢救手术及患者满意度。结果：7项研究共纳入416例病例。两组皮瓣失效及二次抢救手术无显著性差异。然而，tALTF在皮肤移植、供受体部位发病率和患者满意度方面比cufsf有显著优势。结论：该荟萃分析强调了tALTF在重建手术中的临床安全性和优于cufsf的结果，表明其作为外科医生的首选方案。然而，纳入研究的回顾性设计和有限的样本量需要进一步的大规模前瞻性研究来验证这些结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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