Journal of Stomatology Oral and Maxillofacial Surgery最新文献

英文中文

Dexamethasone and concentrated growth factors on peripheral nerve injury: A clinic-relevant animal study 地塞米松和浓缩生长因子对周围神经损伤的影响：临床相关动物研究》。

IF 1.8 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Stomatology Oral and Maxillofacial Surgery

Pub Date : 2024-10-01 DOI: 10.1016/j.jormas.2024.101850

Background

Mandibular nerve injury is a common clinical condition that affects clinicians’ management and patients’ quality of life. In the literature, there are various effective treatments available. The primary purpose of this study was to determine and compare the effects of dexamethasone and concentrated growth factor (CGF) on regeneration in patients with nerve trauma that mimics clinical situations.

Methods

In this study, 36 rats were divided into 3 groups: the control, dexamethasone and CGF groups. The inferior alveolar nerve was traumatized through the extraction socket after mandibular molar tooth extraction in each group.

Results

The data showed a decrease in the control (4.5–4), dexamethasone (3–2), and CGF (4–3) groups according to the histological injury severity score (HISS) results. Compared with those in the other groups, the number of degenerative axons and edematous areas observed via histological examination were significantly lower in the CGF groups. Similarly, compared with those in the control group, the nNOS and Neurofilament-H positivity in the dexamethasone group on the 30th day (2,2 to 1,1 respectively) was significantly lower. The positivity of all the primary antibodies in the 3rd and 30th day CGF groups was significant compared than that in the dexamethasone 30th day group.

Conclusion

According to the results of the analysis of the immunohistopathological and HISS data, the CGF groups exhibited greater regeneration than did the dexamethasone groups.

背景：下颌神经损伤是一种常见的临床症状，影响着临床医生的管理和患者的生活质量。在文献中，有多种有效的治疗方法。本研究的主要目的是模拟临床情况，确定并比较地塞米松和浓缩生长因子（CGF）对神经创伤患者再生的影响：本研究将 36 只大鼠分为 3 组：对照组、地塞米松组和 CGF 组。每组在下颌磨牙拔除后通过拔牙窝对下牙槽神经造成创伤：数据显示，对照组（4.5-4）、地塞米松组（3-2）和 CGF 组（4-3）的组织学损伤严重程度评分（HISS）结果均有所下降。与其他组相比，CGF 组通过组织学检查观察到的退化轴突数量和水肿区域显著减少。同样，与对照组相比，地塞米松组在第 30 天的 nNOS 和 Neurofilament-H 阳性率（分别为 2.2 和 1.1）也明显降低。CGF第3天组和第30天组所有一抗的阳性率均显著高于地塞米松第30天组：根据免疫组织病理学和 HISS 数据的分析结果，CGF 组比地塞米松组表现出更强的再生能力。

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引用次数: 0

ChatGPT revisited: Using ChatGPT-4 for finding references and editing language in medical scientific articles 重温 ChatGPT：使用 ChatGPT-4 查找医学科学文章中的参考文献并编辑语言。

IF 1.8 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Stomatology Oral and Maxillofacial Surgery

Pub Date : 2024-10-01 DOI: 10.1016/j.jormas.2024.101842

The attainment of academic superiority relies heavily upon the accessibility of scholarly resources and the expression of research findings through faultless language usage. Although modern tools, such as the Publish or Perish software program, are proficient in sourcing academic papers based on specific keywords, they often fall short of extracting comprehensive content, including crucial references. The challenge of linguistic precision remains a prominent issue, particularly for research papers composed by non-native English speakers who may encounter word usage errors. This manuscript serves a twofold purpose: firstly, it reassesses the effectiveness of ChatGPT-4 in the context of retrieving pertinent references tailored to specific research topics. Secondly, it introduces a suite of language editing services that are skilled in rectifying word usage errors, ensuring the refined presentation of research outcomes. The article also provides practical guidelines for formulating precise queries to mitigate the risks of erroneous language usage and the inclusion of spurious references. In the ever-evolving realm of academic discourse, leveraging the potential of advanced AI, such as ChatGPT-4, can significantly enhance the quality and impact of scientific publications.

学术优势的获得在很大程度上依赖于学术资源的可获取性，以及通过准确无误的语言表达来表达研究成果。尽管现代工具（如 "出版或毁灭 "软件程序）能根据特定关键词熟练地查找学术论文，但它们往往无法提取包括重要参考文献在内的全面内容。语言精确性的挑战仍然是一个突出的问题，特别是对于母语非英语的研究人员撰写的研究论文，他们可能会遇到用词错误。本手稿有两个目的：首先，它重新评估了 ChatGPT-4 在检索特定研究课题的相关参考文献方面的有效性。其次，它介绍了一套语言编辑服务，这些服务能熟练纠正用词错误，确保研究成果的表述精炼。文章还提供了制定精确查询的实用指南，以降低语言使用错误和包含虚假参考文献的风险。在不断发展的学术话语领域，利用 ChatGPT-4 等先进人工智能的潜力可以大大提高科学出版物的质量和影响力。

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引用次数: 0

Distractor position and distraction amplitude in fronto-facial monobloc advancement : A case series 前颌单体推进术中的牵引位置和牵引幅度：病例系列。

IF 1.8 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Stomatology Oral and Maxillofacial Surgery

Pub Date : 2024-10-01 DOI: 10.1016/j.jormas.2024.101942

Fronto-facial monobloc advancement with internal distraction (FFMBA) is a central procedure in the management of faciocraniosynostoses. In techniques with internal distraction, two sets of devices are generally positioned: bilateral fronto-orbital and temporo-zygomatic distractors, using a temporal tongue and groove osteotomy design. It is believed that distractors must be positioned as parallel as possible in the horizontal and sagittal planes to avoid mechanical conflicts between the sliding bone fragments of the tongue and groove during distraction, and thus optimize the advancement amplitude. Several approaches involving surgical planification and guides for distractor positioning have thus been proposed to monitor distractor placement.

To explore the need for surgical planification in distractor placement, the parallelism of the position of the 4 distractors was assessed in 19 FFMBA procedures and we correlated a set of 10 distractor angles with the degree of advancement.

We report that the horizontal cut of the tongue and groove can be used as a landmark for the positioning of the lower, temporo-zygomatic, distractor in fronto-facial monobloc advancement. Other parameters (relative position of the two homolateral and the two contralateral distractors and the orientations of the vertical and horizontal cuts of the tongue and groove) do not interfere with distraction, other things being equal.

Our results indicate that distractor orientation is not a critical issue in fronto-facial monobloc advancement when devices are positioned as parallel as possible based on visual monitoring.

带内牵引的前额-面部整体推进术（FFMBA）是治疗面颅骨发育不良的核心手术。在内侧牵引技术中，一般会安置两套装置：双侧眶前牵引器和颞颧牵引器，采用颞舌沟截骨设计。一般认为，牵引器必须尽可能在水平面和矢状面上平行定位，以避免牵引过程中舌沟滑动骨片之间的机械冲突，从而优化推进幅度。因此，有人提出了几种方法来监测牵引器的位置，其中包括手术平面化和牵引器定位指南。为了探究牵引器定位是否需要手术规划，我们对 19 例 FFMBA 手术中 4 个牵引器位置的平行度进行了评估，并将一组 10 个牵引器角度与推进程度进行了关联。我们发现，在前牙整体推进术中，舌侧和龈沟的水平切迹可以作为颞颧下牵引器定位的标志。在其他条件相同的情况下，其他参数（两个同侧和两个对侧分心器的相对位置以及舌和舌沟垂直和水平切迹的方向）不会干扰分心。我们的研究结果表明，如果根据视觉监测将装置尽可能平行地定位，分心器的方向并不是前牙单颌前突的关键问题。

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引用次数: 0

Prediction of postoperative dysphagia in patients with oral cancer: A prospective cohort study 口腔癌患者术后吞咽困难的预测：一项前瞻性队列研究。

IF 1.8 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Stomatology Oral and Maxillofacial Surgery

Pub Date : 2024-10-01 DOI: 10.1016/j.jormas.2024.101957

Objectives

This study aims to identify autonomous risk factors for postoperative dysphagia in oral cancer patients and construct a nomogram prediction model to improve risk assessment accuracy and feasibility in clinical settings.

Methods

A prospective cohort study was conducted from March to July 2022 among oral cancer patients undergoing surgical interventions at the Department of Head and Neck Surgery. Clinical data were collected using the Postoperative Dysphagia Risk Factor Questionnaire. Swallowing function was assessed with the Mann Assessment of Swallowing Ability-Oral Cancer (MASA-OC). Lasso regression identified potential predictor variables, followed by univariate and multivariate logistic regression analyses. A predictive model was developed using R Studio 4.1.2 and rigorously evaluated with ROC curves, Hosmer-Lemeshow tests, and calibration curves. Internal validation utilized Bootstrap methodology with 1000 repetitive samples.

Results

The cohort included 257 oral cancer patients, with 73.9 % experiencing postoperative dysphagia. Independent predictors included functional status, depressive symptoms, pT stage, surgical techniques, glossoplasty, maxillectomy, and post-surgery nasopharyngeal tube retention. The predictive model achieved an AUC of 0.933, sensitivity of 90.9 %, and specificity of 81.7 %. Hosmer-Lemeshow test (P = 0.715) and C-index (0.934) indicated satisfactory model fit. Internal validation yielded an AUC of 0.912, sensitivity of 93.3 %, and specificity of 63.8 %. Calibration curves demonstrated alignment between predicted and observed outcomes.

Conclusion

A nomogram integrating recognized risk factors shows promise in predicting postoperative dysphagia in oral cancer patients, enhancing precision and aiding healthcare professionals in risk evaluation and patient care strategies.

目的：本研究旨在确定口腔癌患者术后吞咽困难的自主风险因素，并构建提名图预测模型，以提高临床风险评估的准确性和可行性：本研究旨在确定口腔癌患者术后吞咽困难的自主风险因素，并构建一个提名图预测模型，以提高风险评估的准确性和临床可行性：2022年3月至7月，在头颈外科接受手术治疗的口腔癌患者中开展了一项前瞻性队列研究。使用术后吞咽困难风险因素问卷收集临床数据。吞咽功能采用曼氏吞咽能力评估-口腔癌（MASA-OC）进行评估。拉索回归确定了潜在的预测变量，随后进行了单变量和多变量逻辑回归分析。使用 R Studio 4.1.2 开发了一个预测模型，并通过 ROC 曲线、Hosmer-Lemeshow 检验和校准曲线进行了严格评估。利用 Bootstrap 方法对 1000 个重复样本进行了内部验证：研究对象包括 257 名口腔癌患者，其中 73.9% 的患者在术后出现吞咽困难。独立预测因素包括功能状态、抑郁症状、pT分期、手术技术、舌面成形术、上颌骨切除术和术后鼻咽管保留。预测模型的 AUC 为 0.933，灵敏度为 90.9%，特异性为 81.7%。Hosmer-Lemeshow 检验（P = 0.715）和 C 指数（0.934）表明模型拟合度令人满意。内部验证的 AUC 为 0.912，灵敏度为 93.3%，特异度为 63.8%。校准曲线显示预测结果与观察结果一致：综合公认风险因素的提名图有望预测口腔癌患者术后吞咽困难的情况，从而提高精确度并帮助医护人员进行风险评估和制定患者护理策略。

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引用次数: 0

Pemphigus vulgaris and mucous membrane pemphigoid: A systematic review of clinical manifestations, diagnosis, and treatment 寻常天疱疮和粘膜天疱疮：临床表现、诊断和治疗的系统回顾。

IF 1.8 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Stomatology Oral and Maxillofacial Surgery

Pub Date : 2024-10-01 DOI: 10.1016/j.jormas.2024.101960

Pemphigus vulgaris (PV) and mucous membrane pemphigoid (MMP) are mucocutaneous autoimmune diseases characterized by blistering lesions of mucous membranes and skin, with very similar clinical manifestations. This study aimed to systematically review the literature on the clinical and demographic profile, diagnostic methods, and treatment of patients with pemphigus vulgaris (PV) and mucous membrane pemphigoid (MMP). Studies describing cases of PV and MMP diagnosed by direct immunofluorescence that exhibited intraoral manifestations were included. Thirty-two articles were included, with 18 studies on PV and 15 on MMP, corresponding to 50 and 123 cases diagnosed as PV and MMP, respectively. Most patients with PV (64 %) and MMP (81.3 %) were women in the fifth and sixth decade of life, respectively. The mouth was the primary site of involvement both in PV (71.4 %) and in MMP (91 %). The cheek mucosa and gingiva were the most frequently affected intraoral sites in PV (30 %) and MMP (64.2 %), respectively. Direct immunofluorescence was positive for IgG in all cases of the two conditions. The treatment of choice was systemic corticosteroid therapy for patients with PV (50 %) and topical treatment for patients with MMP (53.7 %). Differences in intraoral site predilection, extraoral involvement, and the results of diagnostic tests allow us to trace the clinical, demographic, and diagnostic profile of PV and MMP that contributes to differential diagnosis and therapeutic management.

寻常型丘疹性荨麻疹（Pemphigus vulgaris，PV）和粘膜丘疹性荨麻疹（Mucous membrane pemphigoid，MMP）是以粘膜和皮肤水疱性病变为特征的粘膜自身免疫性疾病，临床表现非常相似。本研究旨在系统回顾有关寻常型丘疹性荨麻疹（PV）和粘膜丘疹性荨麻疹（MMP）患者的临床和人口统计学特征、诊断方法和治疗的文献。纳入的研究描述了通过直接免疫荧光诊断出的口腔内表现的丘疹性脓疱疮和粘膜丘疹性脓疱疮病例。共纳入 32 篇文章，其中 18 篇研究了口腔黏膜丘疹，15 篇研究了口腔黏膜脓疱病，分别有 50 和 123 个病例被诊断为口腔黏膜丘疹和口腔黏膜脓疱病。大多数 PV（64%）和 MMP（81.3%）患者为女性，年龄分别为五六十岁。在口腔多发性硬化症（71.4%）和口腔黏膜多发性硬化症（91%）中，口腔都是主要受累部位。颊粘膜和牙龈分别是口腔内最常受累的部位，前者为30%，后者为64.2%。在这两种病症的所有病例中，直接免疫荧光均显示 IgG 阳性。口腔多发性硬化症患者的首选治疗方法是全身皮质类固醇治疗（50%），口腔多发性硬化症患者的首选治疗方法是局部治疗（53.7%）。口腔内偏好部位、口腔外受累情况和诊断测试结果的不同，使我们能够追踪 PV 和 MMP 的临床、人口统计学和诊断概况，从而有助于鉴别诊断和治疗管理。

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引用次数: 0

Drug-induced sarcoidosis-like reaction to adalimumab in the oral mucosa of a patient with Crohn's Disease 克罗恩病患者口腔黏膜中药物诱导的阿达木单抗结节病样反应。

IF 1.8 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Stomatology Oral and Maxillofacial Surgery

Pub Date : 2024-10-01 DOI: 10.1016/j.jormas.2023.101543

Background

The drug-induced sarcoidosis-like reaction (DISR) is a condition clinically and pathologically similar to sarcoidosis but is induced by certain drugs. A few cases of DISR associated with the use of TNF-α antagonists have been reported in the literature.

Case report

A 49-year-old female patient with a diagnosis of Crohn's Disease under treatment with adalimumab presented with a 2-month-long ulcerated swelling in the left lower fornix. Histological analysis of the biopsy specimen revealed multiple non-caseating granulomas multinucleated cells and epithelioid macrophages surrounded by lymphocytes. The lesion is under symptomatic control with a topical corticosteroid, and the patient is being monitored for manifestation in other organs and systems.

Conclusion

Lesions of DISR may occur isolated in the oral mucosa. Therefore, this complication must be considered in the differential diagnosis of oral granulomatous lesions in patients under treatment with anti-TNF-α drugs.

背景：药物诱导的结节病样反应（DISR）是一种临床和病理上类似于结节病的疾病，但由某些药物诱导。文献中报道了一些与使用TNF-α拮抗剂相关的DISR病例。病例报告：一名49岁的女性患者，诊断为克罗恩病，在阿达木单抗治疗下，左下穹窿出现长达两个月的溃疡性肿胀。活检标本的组织学分析显示多个非干酪化肉芽肿多核细胞和被淋巴细胞包围的上皮样巨噬细胞。局部皮质类固醇对病变进行症状控制，并监测患者在其他器官和系统中的表现。结论：DISR的病变可能发生在口腔黏膜中。因此，在使用抗TNF-α药物治疗的患者的口腔肉芽肿性病变的鉴别诊断中，必须考虑这种并发症。

引用次数: 0

Mandibular revascularization using a humeral periosteal free flap: A technical note 使用肱骨骨膜游离皮瓣进行下颌骨血管重建：技术说明。

IF 1.8 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Stomatology Oral and Maxillofacial Surgery

Pub Date : 2024-10-01 DOI: 10.1016/j.jormas.2024.101988

Olivier Mathieu , Jean-Philippe Foy , Mourad Benassarou , Paul Moulin , Chloé Bertolus , Thomas Schouman

The vascularized periosteal free flap transposes a non-irradiated soft tissue with neoangiogenesis, bone induction, and osteogenesis qualities. A surgical technique using a humeral periosteal free flap is described for the treatment of recurrent osteoradionecrosis of the lower jaw. The humeral periosteal free flap is a technique associated with low morbidity. The procedure described avoids sacrificing major vessels as seen in other common flap procedures. Hence, this revascularization approach is equivalent to a prevention technique that should be considered early in the development of osteoradionecrosis to avoid further damage and challenging reconstruction.

血管化的骨膜游离瓣移植了非放射软组织，具有新血管生成、骨诱导和骨生成的特质。本文介绍了一种使用肱骨骨膜游离瓣治疗下颌骨复发性骨软化症的手术技术。肱骨骨膜游离瓣是一种发病率较低的技术。所述手术避免了其他常见皮瓣手术中出现的牺牲大血管的情况。因此，这种血管重建方法相当于一种预防技术，应在骨软化症发生的早期就考虑使用，以避免进一步的损伤和重建的挑战。

引用次数: 0

A comparison of ear amputations replantation techniques 耳部截肢再植技术的比较。

IF 1.8 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Stomatology Oral and Maxillofacial Surgery

Pub Date : 2024-10-01 DOI: 10.1016/j.jormas.2023.101497

Background

The management of traumatic ear amputations remains a rare and difficult occurrence for surgeons. This is due to the fact that the chosen replantation technique must ensure the best vascular supply and the surrounding tissues have to be preserved as to not jeopardize a future auricular reconstruction in the event of replantation failure.

Objective

This study aimed to review and synthesize the literature about the different surgical techniques described to date in the management of traumatic ear amputations (partial or total).

Materials and methods

Relevant articles were searched on PubMed, ScienceDirect, and Cochrane Library databases in accordance with the PRISMA statement guidelines.

Results

A total of 67 articles was retained. When possible, microsurgical replantation enabled the best cosmetic result but required important care.

Conclusion

Pocket techniques and local flaps should not be performed because of the lower cosmetic result and the use of the surrounding tissues. However, they could be reserved for patients without access to advanced reconstructive techniques. When possible, microsurgical replantation can be attempted after patient consent for blood transfusions, postoperative care and hospital stay. Simple reattachment for earlobe amputations and ear amputations up to one third is recommended. When microsurgical replantation cannot be attempted, and if the amputated segment is viable and bigger than one third, simple reattachment may be attempted with an increased risk of replantation failure. In case of failure, an auricular reconstruction by an experienced microtia surgeon or prosthesis may be considered.

背景：对于外科医生来说，外伤性耳朵截肢的处理仍然是一种罕见且困难的情况。这是因为所选择的再植技术必须确保最佳的血管供应，并且必须保留周围组织，以免在再植失败的情况下危及未来的耳廓重建。目的：本研究旨在回顾和综合迄今为止描述的不同手术技术在外伤性耳朵截肢（部分或全部）治疗中的文献。材料和方法：根据PRISMA声明指南，在PubMed、ScienceDirect和Cochrane Library数据库中检索相关文章。结果：共保留了67篇文章。在可能的情况下，显微外科再植可以获得最佳的美容效果，但需要重要的护理。结论：不应采用口袋技术和局部皮瓣，因为其美容效果较低，且使用了周围组织。然而，它们可以保留给没有先进重建技术的患者。在可能的情况下，在患者同意输血、术后护理和住院后，可以尝试显微外科再植。建议对耳垂截肢和三分之一以下的耳朵截肢进行简单的复位。当无法尝试显微外科再植时，如果切除的节段是可行的并且大于三分之一，则可以尝试简单的再接，这会增加再植失败的风险。如果失败，可以考虑由经验丰富的耳廓外科医生或假体进行耳廓重建。

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引用次数: 0

Early diagnosis and aggressive surgical resection matters to cure rhinocerebral mucormycosis: Six case reports 早期诊断和积极手术切除是治愈鼻脑粘液瘤病的关键：六份病例报告。

IF 1.8 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Stomatology Oral and Maxillofacial Surgery

Pub Date : 2024-10-01 DOI: 10.1016/j.jormas.2024.101898

Rhino-cerebral mucormycosis (RM) is a rare and opportunistic fungal infection observed in immune-compromised patients and metabolic imbalances such as Diabetes Mellitus. RM rapidly infiltrates blood vessels, leading to vascular thrombosis, subsequent tissue necrosis, and high mortality rates (23.6–60%). Due to its fast advancement, RM is a life-threatening condition requiring accurate clinical decisions by the medical and surgical teams. Based on the report of six cases, we emphasize the need for an early diagnosis and starting antifungal pharmacological therapy at the slightest suspicion of RM. Moreover, the restitution of metabolic balance and aggressive surgical debridement are vital steps to control RM, reducing the possibility of fatal outcomes.

鼻脑粘孢子菌病（RM）是一种罕见的机会性真菌感染，多见于免疫力低下和代谢失衡（如糖尿病）的患者。鼻腔粘液瘤病会迅速浸润血管，导致血管血栓形成、组织坏死和高死亡率（23.6%-60%）。由于其发展迅速，RM 是一种危及生命的疾病，需要内外科团队做出准确的临床决策。根据六例病例的报告，我们强调需要早期诊断，并在最轻微怀疑 RM 时开始抗真菌药物治疗。此外，恢复新陈代谢平衡和积极的手术清创也是控制 RM 的重要步骤，可降低致命后果的可能性。

引用次数: 0

Efficacy of digital zoning design for the resection of benign parotid gland tumor 腮腺良性肿瘤切除术中数字分区设计的有效性

IF 1.8 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Stomatology Oral and Maxillofacial Surgery

Pub Date : 2024-10-01 DOI: 10.1016/j.jormas.2024.101904

The objective of this study is to verify the role of digital modified parotid tumor zoning method in modified parotid incision. The data of patients with parotid benign tumors from November 2021 to December 2023 were collected. Through the use of digital technology for soft tissue reconstruction, the parotid tumor was divided into four areas according to the digital image marker points. We designed the surgical incision according to the parotid gland division, found that it was feasible to guide the incision selection by division, and summarized the common incision and division corresponding, zone I was I and V-shaped incision, zone II was V incision, zone III was V and C- shaped incision, and zone IV was C- shaped incision. We conclude that the digital modified parotid gland zoning method can provide a better distinction in the surgical incision, and provide a better cosmetic incision and prognosis.

本研究旨在验证数字化改良腮腺肿瘤分区法在改良腮腺切口中的作用。收集2021年11月至2023年12月腮腺良性肿瘤患者资料。利用数字化技术进行软组织重建，根据数字化图像标记点将腮腺肿瘤分为四个区域。我们根据腮腺分区设计手术切口，发现以分区指导切口选择是可行的，并总结了常见的切口与分区对应关系，Ⅰ区为Ⅰ型和V型切口，Ⅱ区为V型切口，Ⅲ区为V型和C型切口，Ⅳ区为C型切口。我们的结论是，数字化改良腮腺分区法可以更好地区分手术切口，提供更好的美容切口和预后。

引用次数: 0

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