Journal of Stomatology Oral and Maxillofacial Surgery最新文献

{"title":"The use of bone allograft and platelet-rich fibrin in cleft alveolar bone grafting : an alternative to iliac crest harvesting","authors":"Julie Chauvel-Picard ,&nbsp;Camille Lambert ,&nbsp;Edouard Lange ,&nbsp;Dominique Gaget ,&nbsp;Marc Asselborn ,&nbsp;Chrystele Hartmann-Merlin ,&nbsp;Ahmad B. Alali ,&nbsp;Mohammad Khalaf ,&nbsp;Aqeel A Lari ,&nbsp;Madhi Dashti ,&nbsp;Sanela Morand ,&nbsp;Arnaud Gleizal","doi":"10.1016/j.jormas.2026.102721","DOIUrl":"10.1016/j.jormas.2026.102721","url":null,"abstract":"<div><h3>Introduction</h3><div>Cleft lip and palate (CLP) are congenital anomalies requiring complex multidisciplinary care, including alveolar bone grafting (ABG). ABG restores alveolar continuity, facilitates proper dental alignment and improves nasal function. Traditional autologous bone grafting, often using iliac crest bone, is associated with donor-site morbidity, prompting exploration of alternatives such as bone allografts and biomaterials. This study evaluated the efficacy of bone allograft combined with Platelet-Rich Fibrin (PRF) in pediatric ABG.</div></div><div><h3>Materials and Methods</h3><div>This prospective cohort study included all pediatric patients with unilateral or bilateral CLP undergoing ABG between January 2020 and January 2023. All patients underwent ABG using bone allograft combined with PRF. Pre and postoperative conebeam computed tomography (CBCT) scans were used to assess graft volume and consolidation by quantifying the residual bone allograft. Statistical analyses evaluated factors influencing graft success, including preoperative palatal expansion and cleft characteristics.</div></div><div><h3>Results</h3><div>A total of 47 patients (54 alveolar clefts) were included. The mean residual bone volume was 73.4 +/- 21%. Lateral incisor presence dit not significantly influence graft consolidation, with residual bone volumes of 76.44 +/- 21.01% versus 70.13 +/- 21/14 % (p=0.19). In contrast, preoperative palatal expansion was associated with significantly improved outcomes: patients treated with Quad Helix expansion demonstrated a markedly greater residual bone percentage (79.14 +/- 18.60 % versus 59.77 +/- 20.99 %; p = 0.002; Cohen's d = 1.00). Overall, bone allografts combined with PRF achieved substantial and consistent postoperative ossification with low complications rates with only one case of graft failure.</div></div><div><h3>Conclusion</h3><div>Bone allografts combined with PRF demonstrate satisfactory outcomes in pediatric ABG, offering a viable alternative to autografts. Further studies are needed to evaluate the durability of the grafts, their impact on long-term oral and functional outcomes, and their impact on orthognathic surgery and prosthetic and implant rehabilitation.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 4","pages":"Article 102721"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145999815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and morphometry of mental nerve anterior loop and incisive canal with bone concavity: A radioanatomic study","authors":"Safiye Pelin Sahiner,&nbsp;Gozde Serindere","doi":"10.1016/j.jormas.2026.102727","DOIUrl":"10.1016/j.jormas.2026.102727","url":null,"abstract":"<div><h3>Objective</h3><div>This study evaluates the prevalence and morphology of the mental nerve anterior loop (AL) and incisive canal (IC) using cone-beam computed tomography (CBCT), and their relationship with mandibular bone concavity.</div></div><div><h3>Study Design</h3><div>The CBCT assessment involved measuring the length of the AL, the length and diameter of the IC, together with their distances from the alveolar crest, inferior border, and buccal/lingual cortical plates. Lingual concavity was categorized into four patterns: Type I (lingual), Type II (lingually inclined), Type III (labiolingual expansion), and Type IV (buccal). Data analysis was carried out using SPSS version 29.0.</div></div><div><h3>Results</h3><div>The anterior loop (AL) was observed unilaterally in 52.7% and bilaterally in 29.3% of cases, with mean lengths of 5.47 mm (right) and 5.68 mm (left). The IC was observed in 86.1% of patients, measuring 7.94 mm (right) and 7.67 mm (left) in length and ∼1.5 mm in diameter. Age weakly correlated with some canal measurements; males had slightly larger canal lengths and alveolar crest distances. Concavity type did not significantly affect loop or canal prevalence, though Type III tended to be larger.</div></div><div><h3>Conclusions</h3><div>Mandibular anatomical variations differ by gender, with males showing greater measurements, particularly in cortical distances. Concavity type affects dimensions, with Type III showing the largest values. These findings emphasize the need to consider gender and concavity morphology in preoperative assessment.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 4","pages":"Article 102727"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146004837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Finite element analysis of transnasal, zygomatic and pterygoid implants in the rehabilitation of the atrophic maxilla","authors":"Eren Togac,&nbsp;Ferhat Ayranci,&nbsp;Oguzhan Tapci","doi":"10.1016/j.jormas.2025.102674","DOIUrl":"10.1016/j.jormas.2025.102674","url":null,"abstract":"<div><h3>Aim</h3><div>This study aimed to evaluate the stress distribution generated by transnasal, zygomatic, and pterygoid implants on the implants and surrounding bone in atrophic maxilla models using finite element stress analysis</div></div><div><h3>Materials and methods</h3><div>Three atrophic maxilla models were designed. Model 1 included transnasal implants in regions 12 and 22 and zygomatic implants in regions 15 and 25. Model 2 consisted of four zygomatic implants in regions 12, 15, 22, and 25. Model 3 included transnasal implants in regions 12 and 22, zygomatic implants in regions 15 and 25, and pterygoid implants in regions 17 and 27. A vertical load of 150 N was applied separately to teeth 11 and 16 via a spherical food bolus model</div></div><div><h3>Results</h3><div>The highest Von Mises stress values on implants under both anterior and posterior loading were recorded in Model 1, whereas the lowest values were found in Model 3. For abutments, Model 2 exhibited the highest stress values, while Model 3 showed the lowest. In cortical bone, the highest stress values were observed in Model 2, whereas cancellous bone exhibited the highest stresses in Model 1. The lowest stress values in both bone types were consistently seen in Model 3</div></div><div><h3>Conclusion</h3><div>The combination of transnasal and zygomatic implants may serve as an alternative to the quad zygoma concept. However, incorporating pterygoid implants further reduces stress values and may provide biomechanical advantages in the rehabilitation of the atrophic maxilla.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 3","pages":"Article 102674"},"PeriodicalIF":2.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145679583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The causal link between socioeconomic status and oral cancer risk: Evidence from Mendelian Randomization and global burden of disease analysis (1990–2021)","authors":"Shiqi Li,&nbsp;Jinwei Wang,&nbsp;Xiaoshuai Wei,&nbsp;Zheng Liang","doi":"10.1016/j.jormas.2025.102673","DOIUrl":"10.1016/j.jormas.2025.102673","url":null,"abstract":"<div><h3>Objective</h3><div>Oral cancer shows significant disparities across economic levels and genders. We examine trends and determinants of oral cancer burden in regions with varying Social Development Index (SDI) levels using epidemiological data and Mendelian Randomization (MR).</div></div><div><h3>Methods</h3><div>Data from the 2021 Global Burden of Disease (GBD) dataset were analyzed across various SDI regions. Temporal trends were assessed using annual percentage change (EAPC), and risk factor attribution, decomposition analyses, and age-period-cohort models were conducted. MR were used to examine the causal relationship between economic factors and oral cancer incidence.</div></div><div><h3>Results</h3><div>Oral cancer burden is higher in males. High SDI regions have lower incidence, mortality, and DALYs compared to low SDI regions, with later onset and more pronounced gender differences. Tobacco and alcohol use are major risk factors in high SDI regions, while chewing tobacco predominates in low SDI areas. In low-SDI regions, population growth increases the risk; aging boosts incidence in high-SDI areas. MR analysis showed a negative causal relationship between educational attainment, household income, and oral cancer risk (<em>P</em> &lt; 0.05).</div></div><div><h3>Conclusion</h3><div>Improving socioeconomic factors, particularly education and income, may help prevent oral cancer. The burden is higher in low-SDI regions, among males, and among older people, indicating a need for targeted prevention.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 3","pages":"Article 102673"},"PeriodicalIF":2.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145679529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Toll-like receptors 3, 4, 9 expression with clinicopathological features in oral squamous cell carcinoma","authors":"Melih Solhan ,&nbsp;Betül Öğüt ,&nbsp;Melike Urgancı ,&nbsp;İsmet Bayramoğlu","doi":"10.1016/j.jormas.2025.102688","DOIUrl":"10.1016/j.jormas.2025.102688","url":null,"abstract":"<div><h3>Introduction</h3><div>This study aimed to evaluate the expression levels of Toll-like receptor 3, 4, and 9 in oral cavity squamous cell carcinoma (SCC) and their associations with clinicopathological parameters.</div></div><div><h3>Material and methods</h3><div>Fifty-three patients diagnosed with oral cavity SCC between 2010 and 2015 were retrospectively analyzed. Immunohistochemical staining for TLR-3, TLR-4, and TLR-9 was performed on formalin-fixed, paraffin-embedded tumor tissues. Expression was assessed based on staining intensity, staining status and percentage of positive tumor cells (prevalence). Associations with tumor stage (T, N, TNM), depth of invasion (DOI), lymphovascular invasion (LVI), perineural invasion (PNI), extranodal extension (ENE), histological grade, recurrence, and survival status were evaluated statistically.</div></div><div><h3>Results</h3><div>No statistically significant correlations were found between TLR-3, TLR-4, or TLR-9 expression and any of the examined clinicopathological features (<em>p</em> &gt; 0.05). Although an increasing trend in DOI was observed with stronger TLR-3 and TLR-4 staining, the results were not statistically significant.</div></div><div><h3>Discussion</h3><div>This study did not establish a clear prognostic role for TLR-3, TLR-4, or TLR-9 in oral cavity SCC. However, the findings highlight the biological complexity of TLR-mediated pathways in cancer. Further large-scale, multi-institutional studies are necessary to better understand the clinical relevance of TLRs in oral carcinogenesis.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 3","pages":"Article 102688"},"PeriodicalIF":2.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145800911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An oral microbiome from 1929: Paleoproteomic study of a toothbrush belonging to Georges Clemenceau (1841–1929).","authors":"P Charlier ,&nbsp;L Lentignac ,&nbsp;J Armengaud","doi":"10.1016/j.jormas.2025.102691","DOIUrl":"10.1016/j.jormas.2025.102691","url":null,"abstract":"","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 3","pages":"Article 102691"},"PeriodicalIF":2.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145800916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on “Periauricular incision vs. Modified Blair incision in parotidectomy: A systematic review and meta-analysis of randomized controlled trials”","authors":"Erdem Köroğlu","doi":"10.1016/j.jormas.2025.102683","DOIUrl":"10.1016/j.jormas.2025.102683","url":null,"abstract":"","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 3","pages":"Article 102683"},"PeriodicalIF":2.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145800918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A scoping review of modifications of the transconjunctival approach for maxillofacial fracture management and proposal of evidence-based algorithm for incision selection","authors":"Amanjot Kaur ,&nbsp;Aparna Ganesan ,&nbsp;Karthik Sennimalai ,&nbsp;Kamalpreet Kaur","doi":"10.1016/j.jormas.2025.102670","DOIUrl":"10.1016/j.jormas.2025.102670","url":null,"abstract":"<div><h3>Background</h3><div>The transconjunctival (TC) approach is widely utilized for orbital fracture repair due to its superior cosmetic outcomes compared to cutaneous incisions. However, concerns about limited surgical exposure, prolonged operative times, and lower eyelid complications have prompted several modifications of this technique.</div></div><div><h3>Purpose</h3><div>This scoping review aimed to systematically map and analyze the various modifications of the transconjunctival (TC) approach used for orbital and adjacent midface (infraorbital rim and zygomaticomaxillary complex) fracture repair, focusing on technical descriptions, clinical outcomes, and complications.</div></div><div><h3>Study Selection</h3><div>A systematic search of electronic databases was performed following PRISMA-ScR guidelines to identify studies reporting modifications of the TC approach. Inclusion criteria encompassed clinical studies, retrospective analyses, and case reports or series that described surgical techniques and reported outcomes. Studies describing TC approach modifications for orbital, infraorbital rim, or zygomatic fractures were included. Studies without specific details on modifications or outcomes were excluded. Of the initially identified articles, 22 studies met the inclusion criteria after independent screening by two reviewers.</div></div><div><h3>Results</h3><div>Twenty-two studies describing TC approach modifications were included, describing eight major categories of TC modifications. Reported variations included lateral paracanthal extensions, sutureless TC incisions, cutaneous Y-modifications, extended TC approaches, stair-step incisions, modified lateral canthotomy and aesthetic variations, lateral skin extensions and canthal-sparing techniques. These techniques were designed to improve surgical access and minimise complications such as ectropion, entropion, and scleral show. Some modifications prioritized enhanced exposure, while others focused on reducing morbidity and optimizing aesthetic results. Due to the heterogeneity of study designs and outcome measures, quantitative synthesis was not performed.</div></div><div><h3>Conclusions and Relevance</h3><div>The TC approach continues to evolve through multiple technical refinements that balance exposure and aesthetics. Awareness of these variants enables surgeons to individualise incision choices based on fracture patterns and risk profiles. The current evidence is largely descriptive and lacks standardised outcome measures, which limits direct comparisons. Prospective, well-designed studies are needed to establish the optimal modification for specific clinical contexts.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 3","pages":"Article 102670"},"PeriodicalIF":2.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145643149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomechanical evaluation of reconstruction plates in bone-grafted mandibular defects: a finite element analysis","authors":"Diogo de Vasconcelos Macedo ,&nbsp;Milena Gomes Melo Leite ,&nbsp;Maria Eduarda Carlos Conceição ,&nbsp;Nicolau Conte Neto ,&nbsp;Marcelo Silva Monnazzi","doi":"10.1016/j.jormas.2026.102716","DOIUrl":"10.1016/j.jormas.2026.102716","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate, through three-dimensional finite element analysis (FEA), the stress and strain distribution in reconstruction plates of different thicknesses used for fixation of bone-grafted segmental mandibular defects.</div></div><div><h3>Method</h3><div>A dentate mandibular model was obtained from computed tomography data and digitally processed for FEA using ANSYS 7.0. Three reconstruction plate models (2.0, 2.4, and 3.0 mm thick) were applied to simulate defects in the symphyseal, body, and angle regions of the mandible, each associated with block bone grafts and fixed using 2.4-mm locking screws. A 300-N vertical occlusal load and muscle vectors representing masticatory forces were simulated. Stress distribution was analyzed according to von Mises criteria across plates, screws, and bone graft blocks.</div></div><div><h3>Results</h3><div>Increasing plate thickness reduced stress concentration within the plates but significantly increased stress on the fixation screws, particularly those adjacent to osteotomy lines. The symphyseal defect exhibited the highest stress values, followed by the body and angle defects. Stress values within bone graft blocks remained low (&lt;250 MPa), indicating minimal deformation.</div></div><div><h3>Conclusion</h3><div>Thicker reconstruction plates enhance mechanical resistance but increase stress concentration on fixation screws, especially near osteotomies, suggesting a higher risk of screw loosening or peri‑implant bone resorption. The anterior mandible demonstrated the most unfavorable stress distribution. Locking fixation systems are recommended when rigid plates are used to mitigate screw-related complications.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 3","pages":"Article 102716"},"PeriodicalIF":2.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145992109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinicopathological analysis and survival outcomes of head and neck spindle cell carcinoma: A systematic review","authors":"Moisés Willian Aparecido Gonçalves ,&nbsp;Iara Vieira Ferreira ,&nbsp;Reydson Alcides de Lima-Souza ,&nbsp;Guilherme Arruda Vieira ,&nbsp;Marcelo Elias Schempf Cattan ,&nbsp;Natália Vital Gonçalves ,&nbsp;Carlos Takahiro Chone ,&nbsp;Alfio José Tincani ,&nbsp;Arthur Antolini-Tavares ,&nbsp;Erika Said Abu Egal ,&nbsp;Albina Altemani ,&nbsp;Fernanda Viviane Mariano","doi":"10.1016/j.jormas.2025.102695","DOIUrl":"10.1016/j.jormas.2025.102695","url":null,"abstract":"<div><h3>Background</h3><div>This systematic review aimed to summarize the clinicopathological characteristics, molecular profile, treatment, and outcomes of head and neck spindle cell carcinoma (HNSpCC).</div></div><div><h3>Methods</h3><div>A comprehensive search was performed in five databases and gray literature (December 2024). Associations between clinical variables were tested using Fisher’s exact and Chi-square tests, and survival was analyzed with the Kaplan-Meier method.</div></div><div><h3>Results</h3><div>Thirty-nine studies reporting 2,250 cases were included. HNSpCC primarily affects adult males, with the larynx being the most common site, followed by the oral cavity and oropharynx, often presenting as polypoid/exophytic tumors. Diagnosis requires careful use of immunohistochemistry, especially vimentin and epithelial markers. Genetic alterations included <em>TP53, EGFR, ALK</em>, and <em>PIK3CA</em> mutations. Surgery was the main treatment; however, local recurrences, regional and distant metastases were frequent. Survival outcomes were influenced by tumor site, stage, and recurrence. Oral cavity tumors showed the worst prognosis, while laryngeal tumors had comparatively better survival.</div></div><div><h3>Conclusions</h3><div>HNSpCC is an aggressive malignancy with poor outcomes, especially in advanced-stage and oral cavity cases.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 3","pages":"Article 102695"},"PeriodicalIF":2.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145844232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}