Pregnancy complicated by fetal goiter following lung transplantation for idiopathic pulmonary arterial hypertension: A case study

IF 2.2 4区医学 Q2 OBSTETRICS & GYNECOLOGY Taiwanese Journal of Obstetrics & Gynecology Pub Date : 2025-01-01 DOI:10.1016/j.tjog.2024.08.007

Asuka Hamuro , Yoshifumi Kasuga , Saki Saito , Hiroshi Uchida , Takahiro Hiraide , Yohei Yamada , Takeshi Arimitsu , Hiroshi Date , Hiroyuki Fukushima , Mamoru Tanaka

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Abstract

Objective

We report a case of pregnancy following lung transplantation (LT) for idiopathic pulmonary arterial hypertension (IPAH) in Japan.

Case Report

A female developed IPAH at 14 years of age and underwent a successful bilateral living-donor lobar LT from her parents at 19 years of age (gravida 2, para 0). At the age of 40 years, the patient became pregnant via artificial insemination. At 28 weeks of gestation, polyhydramnios and a fetal goiter were detected on transabdominal ultrasound. The patient was diagnosed with deep vein thrombosis and pulmonary embolism. The patient underwent emergency cesarean section to deliver a male neonate weighing 1340 g (−0.41SD) at 30 weeks of gestation, with an Apgar score of 5/5 (1/5 min).

Conclusion

To our knowledge, this is the first reported case of a successful pregnancy following LT in Japan. Specialists should work together to manage pregnancies following LT.

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特发性肺动脉高压肺移植术后妊娠合并胎儿甲状腺肿一例研究。

目的：我们报告一例日本特发性肺动脉高压（IPAH）患者肺移植（LT）后妊娠。病例报告：一名女性在14岁时患上IPAH，并在19岁时成功接受了父母的双侧活体肝移植（妊娠2，第0段）。在40岁时，患者通过人工授精怀孕。妊娠28周时，经腹超声检查发现羊水过多和胎儿甲状腺肿大。患者被诊断为深静脉血栓形成和肺栓塞。患者于妊娠30周行紧急剖宫产术，生下体重1340 g （-0.41SD）的男婴，Apgar评分为5/5 （1/5 min）。结论：据我们所知，这是日本首次报道的肝移植后妊娠成功的病例。专家们应该共同努力来管理术后妊娠。

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来源期刊

Taiwanese Journal of Obstetrics & Gynecology OBSTETRICS & GYNECOLOGY-

CiteScore

3.60

自引率

23.80%

发文量

207

审稿时长

4-8 weeks

期刊介绍： Taiwanese Journal of Obstetrics and Gynecology is a peer-reviewed journal and open access publishing editorials, reviews, original articles, short communications, case reports, research letters, correspondence and letters to the editor in the field of obstetrics and gynecology. The aims of the journal are to: 1.Publish cutting-edge, innovative and topical research that addresses screening, diagnosis, management and care in women''s health 2.Deliver evidence-based information 3.Promote the sharing of clinical experience 4.Address women-related health promotion The journal provides comprehensive coverage of topics in obstetrics & gynecology and women''s health including maternal-fetal medicine, reproductive endocrinology/infertility, and gynecologic oncology. Taiwan Association of Obstetrics and Gynecology.