From plankton to fish: The multifaceted threat of microplastics in freshwater environments

Abstract

The detrimental impact of emerging pollutants, specifically microplastics (MPs), on the ecological environment are receiving increasing attention. Freshwater ecosystems serve as both repositories for terrestrial microplastic (MP) sources and conduits for their subsequent entry into marine environments. Consequently, it is imperative to rigorously investigate the toxicological effects of MPs on freshwater ecosystems. This article provides a comprehensive analysis of the ecological toxicity effects of MP pollution, both in isolation and in combination with other pollutants, on freshwater aquatic organisms, including plankton, benthic organisms, and fish. The review elucidates potential mechanisms underlying these effects, which encompass oxidative stress, metabolic disorders, immune and inflammatory responses, dysbiosis of the gut microbiota, DNA damage, and cell apoptosis. This paper advocates for the integrated application of multi-omics technologies to investigate the molecular mechanisms underlying the toxicity of MPs to freshwater aquatic organisms from interdisciplinary and multifaceted perspectives. Additionally, it emphasizes the importance of enhancing research on the compounded pollution effects arising from various pollution modes, particularly in conjunction with other pollutants. This study aims to establish a foundation for assessing the ecological risks posed by MPs in freshwater ecosystem and offers valuable insights for the protection of aquatic biodiversity and ecosystem stability.