Buried or exposed kirschner wires in paediatric upper extremity fracture fixation: A systematic review and meta-analysis of infection rates and complications.

Jack Pullan, Olusegun Ayeko, James Metcalfe
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引用次数: 0

Abstract

Background: Paediatric upper limb fractures are commonly treated with Kirschner (K) wire fixation, which can be buried or left exposed. Although both techniques are widely used, controversy remains regarding infection risk, complications, and other clinical outcomes between buried and exposed K-wires. This systematic review and meta-analysis aimed to compare infection rates and secondary outcomes between buried and exposed K-wires in paediatric upper limb fractures located distal to and including the elbow, and proximal to the carpus.

Methods: A systematic review of the literature was conducted according to PRISMA guidelines, with searches performed across Medline, EMBASE, and the Cochrane Library up to July 2023. Studies were included if they directly compared buried and exposed K-wires in paediatric patients (under 18 years old) and reported on infection rates. Meta-analysis was conducted to compare overall infection rates. Pooled means were used to compare secondary outcomes. Bias was assessed using the ROBINS-I and RoB2 tools.

Results: Fifteen studies involving 1,854 participants were included. The meta-analysis showed that buried K-wires were associated with a significantly lower risk of overall postoperative infection compared to exposed K-wires (RR 0.33; 95 % CI 0.22 to 0.50; p< 0.001). The risk of deep infection requiring further surgery was 1.74 % in buried K-wires (95 % CI: 0.72 % to 2.75 %) and 2.07 % in exposed K-wires (95 % CI: 0.55 % to 3.59 %). Skin erosion was a common complication of buried K-wires, with a pooled mean rate of 13.0 %. Buried K-wires were associated with a higher likelihood of requiring removal in theatre (84.4 % vs. 4.2 %). Time to K-wire removal was longer in the buried group (10.9 weeks vs. 5.3 weeks). Re-operation and bone union failure rates were similar between groups.

Conclusion: Our systematic review and meta-analysis suggest that, while buried K-wires are associated with lower overall infection rates, the risk of deep infection is comparable between buried and exposed K-wires. Buried K-wires show higher rates of skin erosion and increased need for removal in theatre. Given these findings, exposed K-wires offer a safe and more cost-effective option for paediatric upper limb fracture fixation. Further studies are needed to assess patient-reported outcomes and environmental impacts.

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埋入或外露克氏针用于小儿上肢骨折固定:感染率和并发症的系统回顾和荟萃分析。
背景:小儿上肢骨折通常采用克氏针固定治疗,克氏针可以埋入或暴露。尽管这两种技术都被广泛使用,但关于埋入和外露k线的感染风险、并发症和其他临床结果仍存在争议。本系统综述和荟萃分析旨在比较埋入式和外露式k针治疗位于肘关节远端和腕骨近端儿童上肢骨折的感染率和继发结局。方法:根据PRISMA指南对文献进行系统综述,并在Medline、EMBASE和Cochrane图书馆进行检索,检索截止到2023年7月。如果研究直接比较埋入的和暴露的k线在儿童患者(18岁以下)中,并报告感染率,则纳入研究。进行meta分析比较总体感染率。采用合并方法比较次要结局。使用ROBINS-I和RoB2工具评估偏倚。结果:纳入了15项研究,涉及1854名受试者。荟萃分析显示,与暴露的k -钢丝相比,埋入k -钢丝与总体术后感染风险显著降低相关(RR 0.33;95% CI 0.22 ~ 0.50;p < 0.001)。深埋k线组需要进一步手术的深度感染风险为1.74% (95% CI: 0.72% ~ 2.75%),外露k线组为2.07% (95% CI: 0.55% ~ 3.59%)。皮肤糜烂是埋置k针的常见并发症,平均发生率为13.0%。埋置k线患者需要在手术室取出的可能性更高(84.4%对4.2%)。埋置组取丝时间较长(10.9周比5.3周)。两组间再手术及骨愈合失败率相似。结论:我们的系统回顾和荟萃分析表明,虽然埋置k线与较低的总体感染率相关,但埋置k线与暴露k线之间的深度感染风险相当。埋藏的k线显示出更高的皮肤侵蚀率,并且在手术室中需要更多的取出k线。鉴于这些发现,外露k针为儿童上肢骨折固定提供了安全且更具成本效益的选择。需要进一步的研究来评估患者报告的结果和环境影响。
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