{"title":"ELL3 regulates spindle assembly to prevent maternally inherited aneuploidy and infertility","authors":"Bernhard Magerl, Tommaso Cavazza","doi":"10.1038/s41594-024-01475-4","DOIUrl":null,"url":null,"abstract":"Aneuploidy is a major cause of embryonic failure and miscarriage. A new study identifies genetic variants of ELL3 associated with miscarriage and discovers a novel role for ELL3 in female meiosis.","PeriodicalId":18822,"journal":{"name":"Nature structural & molecular biology","volume":"129 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature structural & molecular biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1038/s41594-024-01475-4","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Aneuploidy is a major cause of embryonic failure and miscarriage. A new study identifies genetic variants of ELL3 associated with miscarriage and discovers a novel role for ELL3 in female meiosis.
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