Sesterterpenoids: sources, structural diversity, biological activity, and data management.

IF 10.2 1区 化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Natural Product Reports Pub Date : 2025-01-20 DOI:10.1039/d4np00041b
Valeria Iobbi, Valentina Parisi, Mauro Giacomini, Francesco De Riccardis, Paola Brun, Laura Núñez-Pons, Giuliana Drava, Paolo Giordani, Maria Chiara Monti, Roberto Poggi, Ylenia Murgia, Nunziatina De Tommasi, Angela Bisio
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Abstract

Reviewing the literature published up to October 2024.Sesterterpenoids are one of the most chemically diverse and biologically promising subgroup of terpenoids, the largest family of secondary metabolites. The present review article summarizes more than seven decades of studies on isolation and characterization of more than 1600 structurally novel sesterterpenoids, supplemented by biological, pharmacological, ecological, and geographic distribution data. All the information have been implemented in eight tables available on the web and a relational database https://sesterterpenoids.unige.net/. The interface has two sections, one open to the public for reading only and the other, protected by an authentication mechanism, for timely updating of published results.

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来源期刊
Natural Product Reports
Natural Product Reports 化学-生化与分子生物学
CiteScore
21.20
自引率
3.40%
发文量
127
审稿时长
1.7 months
期刊介绍: Natural Product Reports (NPR) serves as a pivotal critical review journal propelling advancements in all facets of natural products research, encompassing isolation, structural and stereochemical determination, biosynthesis, biological activity, and synthesis. With a broad scope, NPR extends its influence into the wider bioinorganic, bioorganic, and chemical biology communities. Covering areas such as enzymology, nucleic acids, genetics, chemical ecology, carbohydrates, primary and secondary metabolism, and analytical techniques, the journal provides insightful articles focusing on key developments shaping the field, rather than offering exhaustive overviews of all results. NPR encourages authors to infuse their perspectives on developments, trends, and future directions, fostering a dynamic exchange of ideas within the natural products research community.
期刊最新文献
Back cover Enzymatic ester bond formation strategies in fungal macrolide skeletons. Human milk as a complex natural product. Sesterterpenoids: sources, structural diversity, biological activity, and data management. Unlocking hidden treasures: the evolution of high-throughput mass spectrometry in screening for cryptic natural products.
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