Co-infections of Enterococcus cecorum and various avian pathogens resulted in varying rates of SPF broilers with an E. cecorum infection.

IF 2.5 2区农林科学 Q1 VETERINARY SCIENCES Avian Pathology Pub Date : 2025-01-29 DOI:10.1080/03079457.2025.2450428

Thijs Manders, Merlijn Kense, Remco Dijkman, Jeanine Wiegel, Mieke Matthijs, Sjaak de Wit

引用次数: 0

Abstract

Research highlights: Typical E. cecorum lesions can be reproduced in SPF broilers after intravenous, aerosol and oral inoculations.The respiratory route is potentially an infection route for pathogenic E. cecorum bacteria.Co-infections tested in this study or dexamethasone do not exacerbate the proportion of E. cecorum lesions.M.s. in combination with IBV or NDV vaccines exacerbates the proportion of positive reisolations.Immunosuppression induced by early CAV infection increases the proportion of positive reisolations.

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盲肠球菌与多种禽类病原体的共同感染导致SPF级肉鸡盲肠球菌感染的发生率不同。

肠球菌感染经口服接种后可实验性繁殖。盲肠肠杆菌与其他禽类病原体的共感染可能会增加盲肠肠杆菌感染肉鸡的比例。本研究的目的是研究盲肠大肠杆菌通过哪种感染途径能够引起盲肠大肠杆菌感染，以及哪种合并感染会加剧盲肠大肠杆菌感染。进行2个实验，每组12组。每组40只SPF级肉鸡分别通过静脉、口服或气雾剂单独接种盲肠杆菌，并设阴性对照组，分8组研究共感染的效果。实验1，在口服或气雾剂攻毒前分别接种传染性支气管炎病毒（IBV）、新城疫病毒（NDV）疫苗、呼肠孤病毒、鸡贫血病毒（CAV）。在实验2中，给药地塞米松或接种CAV或IBV或NDV与滑膜支原体（Mycoplasma synoviae， M.s.）联合接种盲肠肠杆菌。所有感染途径均可复制典型盲肠大肠杆菌病变。静脉接种组的病变比例最高，分别为0.25（95%可信区间0.127 ~ 0.412）和0.275（95%可信区间0.146 ~ 0.439）。实验2中观察到的病变更多，而口服和气溶胶接种后的病变比例在两个实验中没有差异。盲肠大肠杆菌与多种禽类病原体共感染后，病变比例未增加。CAV或ms与IBV或NDV联合接种后，只有盲肠大肠杆菌的再分离比例增加。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Avian Pathology 农林科学-兽医学

CiteScore

4.50

自引率

10.70%

发文量

审稿时长

1 months

期刊介绍： Avian Pathology is the official journal of the World Veterinary Poultry Association and, since its first publication in 1972, has been a leading international journal for poultry disease scientists. It publishes material relevant to the entire field of infectious and non-infectious diseases of poultry and other birds. Accepted manuscripts will contribute novel data of interest to an international readership and will add significantly to knowledge and understanding of diseases, old or new. Subject areas include pathology, diagnosis, detection and characterisation of pathogens, infections of possible zoonotic importance, epidemiology, innate and immune responses, vaccines, gene sequences, genetics in relation to disease and physiological and biochemical changes in response to disease. First and subsequent reports of well-recognized diseases within a country are not acceptable unless they also include substantial new information about the disease or pathogen. Manuscripts on wild or pet birds should describe disease or pathogens in a significant number of birds, recognizing/suggesting serious potential impact on that species or that the disease or pathogen is of demonstrable relevance to poultry. Manuscripts on food-borne microorganisms acquired during or after processing, and those that catalogue the occurrence or properties of microorganisms, are unlikely to be considered for publication in the absence of data linking them to avian disease.