Rational use of human albumin: plan-do-check-act cycle in clinical practice.

IF 2 4区医学 Q3 HEALTH CARE SCIENCES & SERVICES BMJ Supportive & Palliative Care Pub Date : 2025-01-20 DOI:10.1136/spcare-2024-005268

Xiaowei Huang, Xuehui Jiang, Fangfang Xiong, Xinyang Fu, Lei Hong, Xiaohui Xu, Zhihang Lin

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Abstract

Objective: Improper use of human albumin (HA) is now common in clinical settings. This study aims to explore the feasibility of the plan-do-check-act (PDCA) cycle in promoting the rational use of HA.

Methods: The differences between the control and observation groups (after the PDCA cycle) in terms of serum albumin detection rate, serum albumin values, HA usage, and rationality were analysed and compared using a before-and-after control method.

Results: A total of 372 patients were recruited, including 186 in each of the control and observation groups. On comparison, it was observed that the overall use of HA improved after the PDCA cycle compared with the preintervention period, and the rational rate of HA prescriptions increased from 68.3% to 96.2%. The serum albumin detection rate before applying for HA increased from 83.9% to 98.9%, and the median values decreased from 26.7 (22.8-30.9) g/L to 24.7 (22.7-27.2) g/L. Regarding the use of HA, the median amount of HA used was reduced by 20 g compared with the preintervention period, meanwhile, the median duration was shortened by 2 days.

Conclusion: The PDCA cycle is desirable when employed to promote the rational use of HA.

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人白蛋白的合理使用：临床实践中的计划-执行-检查-行动循环。

目的：人白蛋白（HA）的不当使用目前在临床环境中很常见。本研究旨在探讨计划-执行-检查-行动（PDCA）循环在促进医院合理利用方面的可行性。方法：采用前后对照法，分析比较对照组与观察组（PDCA循环后）血清白蛋白检出率、血清白蛋白值、血凝素使用及合理性的差异。结果：共纳入372例患者，对照组和观察组各186例。对比发现，与干预前相比，PDCA循环后HA的整体利用率有所提高，HA处方的合理使用率从68.3%提高到96.2%。应用HA前血清白蛋白检出率由83.9%上升至98.9%，中位数由26.7 (22.8-30.9)g/L下降至24.7 (22.7-27.2)g/L。在HA使用方面，与干预前相比，HA使用量中位数减少了20 g，持续时间中位数缩短了2天。结论：采用PDCA循环促进HA的合理使用是可取的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMJ Supportive & Palliative Care Medicine-Medicine (miscellaneous)

CiteScore

4.60

自引率

7.40%

发文量

170

期刊介绍： Published quarterly in print and continuously online, BMJ Supportive & Palliative Care aims to connect many disciplines and specialties throughout the world by providing high quality, clinically relevant research, reviews, comment, information and news of international importance. We hold an inclusive view of supportive and palliative care research and we are able to call on expertise to critique the whole range of methodologies within the subject, including those working in transitional research, clinical trials, epidemiology, behavioural sciences, ethics and health service research. Articles with relevance to clinical practice and clinical service development will be considered for publication. In an international context, many different categories of clinician and healthcare workers do clinical work associated with palliative medicine, specialist or generalist palliative care, supportive care, psychosocial-oncology and end of life care. We wish to engage many specialties, not only those traditionally associated with supportive and palliative care. We hope to extend the readership to doctors, nurses, other healthcare workers and researchers in medical and surgical specialties, including but not limited to cardiology, gastroenterology, geriatrics, neurology, oncology, paediatrics, primary care, psychiatry, psychology, renal medicine, respiratory medicine.