Ivana Pajic-Lijakovic, Milan Milivojevic, Peter V E McClintock
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引用次数: 0
Abstract
Friction is a critical factor in the proper functioning of human organs as well as in the potential development of disease. It is also important for the design of diagnostic and interventional medical devices. Nanoscale surface roughness, viscoelastic or plastic deformations, wear, and lubrication all influence the functions of individual cells. The effects of friction in soft matter systems are quantified using different types of frictional coefficients, including the dynamic friction coefficient, friction-skin drag, and pressure drag. These coefficients are determined by the viscoelastic properties of the two systems in contact and their relative velocity. In this review, several biological systems are considered, including (i) epithelial tissues in contact with soft hydrogel-like implants, (ii) the collective migration of epithelial monolayers on substrate matrices, (iii) blood flow through blood vessels, and (iv) the movement of cancer cells past epithelial clusters along with the migration of epithelial cells within the cluster.
期刊介绍：
Biophysical Reviews aims to publish critical and timely reviews from key figures in the field of biophysics. The bulk of the reviews that are currently published are from invited authors, but the journal is also open for non-solicited reviews. Interested authors are encouraged to discuss the possibility of contributing a review with the Editor-in-Chief prior to submission. Through publishing reviews on biophysics, the editors of the journal hope to illustrate the great power and potential of physical techniques in the biological sciences, they aim to stimulate the discussion and promote further research and would like to educate and enthuse basic researcher scientists and students of biophysics. Biophysical Reviews covers the entire field of biophysics, generally defined as the science of describing and defining biological phenomenon using the concepts and the techniques of physics. This includes but is not limited by such areas as: - Bioinformatics - Biophysical methods and instrumentation - Medical biophysics - Biosystems - Cell biophysics and organization - Macromolecules: dynamics, structures and interactions - Single molecule biophysics - Membrane biophysics, channels and transportation
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