Utility of the 6-Min Walk Test for Assessing Physical Performance in Pediatric Heart Transplant Recipients

IF 1.9 4区医学 Q2 SURGERY Clinical Transplantation Pub Date : 2025-01-20 DOI:10.1111/ctr.70061

Heidi Mäenpää, Tiina Ojala, Juuso Tainio, Jari Arokoski, Timo Jahnukainen

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Abstract

Background

Physical performance capacity (PPC) of pediatric heart transplant (HT) recipients is reportedly low to normal, and longitudinal follow-up of these patients is recommended. However, no recommendation for a follow-up method is available. In this study, the correlation between the 6-min walk test (6MWT), various clinical parameters, and a physical performance test set was evaluated to develop a simple follow-up tool for PPC.

Methods

Fifteen pediatric HT patients and 392 historical controls were tested at a median age of 15.4 years. PPC was tested with a 6MWT and a physical performance test set consisting of six different components assessing muscle endurance, strength, speed, and flexibility.

Results

Controls outperformed recipients across all test domains except the leg lift and sit-and-reach test. The 6MWT distance correlated well with the physical performance test set results; the correlations were with leg lift (r_s = 0.622, p = <0.05), repeated squatting (r_s = 0.851, p = <0.001, sit-up (r_s = 0.738, p = <0.05), back extension (r_s = 0.747, p ≤ 0.001), and total physical performance capacity (r_s = 0.873, p = <0.001). Indexed 6MWT results or total physical performance capacity set had no statistically significant associations with any of the clinical parameters tested.

Conclusion

Our study supports recent findings suggesting that the 6MWT is a suitable method for longitudinal follow-up in children with HT. We recommend performing the 6MWT annually in these patients, to be used to motivate and encourage them to enhance their physical activity.

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6分钟步行测试评估儿童心脏移植受者身体表现的效用。

背景：据报道，儿童心脏移植（HT）受者的身体运动能力（PPC）较低至正常，建议对这些患者进行纵向随访。然而，没有关于后续方法的建议。在本研究中，我们评估了6分钟步行试验（6MWT）、各种临床参数和体能测试集之间的相关性，以开发一种简单的PPC随访工具。方法：对15例儿童HT患者和392例既往对照组进行了测试，中位年龄为15.4岁。PPC测试采用6MWT和物理性能测试集，包括六个不同的组件评估肌肉耐力，力量，速度和柔韧性。结果：控制组在所有测试领域的表现都优于接受者，除了抬腿和坐伸测试。6MWT距离与物理性能测试集结果相关性较好；相关性与腿举（rs = 0.622, p = s = 0.851, p = s = 0.738, p = s = 0.747, p≤0.001）和总体能（rs = 0.873, p = 0.001）有关。结论：我们的研究支持了最近的研究结果，表明6MWT是一种适用于HT儿童纵向随访的方法。我们建议这些患者每年进行6MWT，以激励和鼓励他们加强身体活动。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Transplantation 医学-外科

CiteScore

3.70

自引率

4.80%

发文量

286

审稿时长

2 months

期刊介绍： Clinical Transplantation: The Journal of Clinical and Translational Research aims to serve as a channel of rapid communication for all those involved in the care of patients who require, or have had, organ or tissue transplants, including: kidney, intestine, liver, pancreas, islets, heart, heart valves, lung, bone marrow, cornea, skin, bone, and cartilage, viable or stored. Published monthly, Clinical Transplantation’s scope is focused on the complete spectrum of present transplant therapies, as well as also those that are experimental or may become possible in future. Topics include: Immunology and immunosuppression; Patient preparation; Social, ethical, and psychological issues; Complications, short- and long-term results; Artificial organs; Donation and preservation of organ and tissue; Translational studies; Advances in tissue typing; Updates on transplant pathology;. Clinical and translational studies are particularly welcome, as well as focused reviews. Full-length papers and short communications are invited. Clinical reviews are encouraged, as well as seminal papers in basic science which might lead to immediate clinical application. Prominence is regularly given to the results of cooperative surveys conducted by the organ and tissue transplant registries. Clinical Transplantation: The Journal of Clinical and Translational Research is essential reading for clinicians and researchers in the diverse field of transplantation: surgeons; clinical immunologists; cryobiologists; hematologists; gastroenterologists; hepatologists; pulmonologists; nephrologists; cardiologists; and endocrinologists. It will also be of interest to sociologists, psychologists, research workers, and to all health professionals whose combined efforts will improve the prognosis of transplant recipients.