The roles of impulsivity, comorbid ADHD, and borderline personality disorder in patients with bulimia nervosa.

Susanne Gilsbach, Julia Leuchtenberger, Beate Herpertz-Dahlmann, Ulrich Voderholzer, Kerstin Konrad, Georg von Polier, Jochen Seitz, Manfred Fichter
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Abstract

Background: Bulimia nervosa (BN) is a serious mental illness with impulsivity as a cardinal symptom. Impulsivity contributes to various other, often comorbid, mental disorders, such as attention deficit/hyperactivity disorder (ADHD) and borderline personality disorder (BPD). The aim of this study was to explore comorbidities of BN with ADHD and BPD as well as the contribution of impulsivity as an underlying trait linking these disorders.

Methods: Hundred and fifteen females with BN and 98 healthy matched controls (HC) (age range between 16 and 48 years) were assessed regarding adult and childhood-ADHD, personality disorders and impulsivity.

Results: Patients with BN were more impulsive (p < 0.001) and more often fulfilled criteria of childhood/adulthood ADHD (p < 0.001) than HC, and criteria of BPD than expected in the general population. Childhood-ADHD (p = 0.009) and BPD (p = 0.017) both were significant positive predictors for impulsivity scores found in patients with BN.

Conclusion: Comorbidity with ADHD and BPD often is prevalent in BN and associated with an increase in impulsivity, the latter being a relevant transdiagnostic trait. It might be beneficial to explore impulsivity as well as comorbidities in the clinical care of patients with BN.

Level of evidence iii: Evidence obtained from well-designed cohort or case-control analytic studies.

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冲动、共病性ADHD和边缘性人格障碍在神经性贪食症患者中的作用。
背景:神经性贪食症(BN)是一种以冲动为主要症状的严重精神疾病。冲动会导致其他各种精神障碍,通常是共病,比如注意力缺陷/多动障碍(ADHD)和边缘型人格障碍(BPD)。本研究的目的是探讨BN与ADHD和BPD的合并症,以及冲动性作为联系这些疾病的潜在特征的贡献。方法:对115名BN女性和98名健康匹配对照(HC)(年龄在16 ~ 48岁之间)进行成人和儿童adhd、人格障碍和冲动的评估。结果:BN患者更易冲动(p结论:BN患者常伴有ADHD和BPD的共病,且与冲动性增加有关,后者是一种相关的跨诊断特征。探讨冲动性及其合并症在BN患者的临床护理中可能是有益的。证据水平iii:证据来自设计良好的队列研究或病例对照分析研究。
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来源期刊
CiteScore
6.50
自引率
10.30%
发文量
170
审稿时长
>12 weeks
期刊介绍: Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity is a scientific journal whose main purpose is to create an international forum devoted to the several sectors of eating disorders and obesity and the significant relations between them. The journal publishes basic research, clinical and theoretical articles on eating disorders and weight-related problems: anorexia nervosa, bulimia nervosa, subthreshold eating disorders, obesity, atypical patterns of eating behaviour and body weight regulation in clinical and non-clinical populations.
期刊最新文献
Early intervention in eating disorders: introducing the chronopathogram. The risk of believing that emotions are bad and uncontrollable: association with orthorexia nervosa. The roles of impulsivity, comorbid ADHD, and borderline personality disorder in patients with bulimia nervosa. Eating behavior patterns, metabolic parameters and circulating oxytocin levels in patients with obesity: an exploratory study. Perfectionism and compulsive exercise: a systematic review and preliminary meta-analysis.
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