Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity最新文献

Purpose: This study examined the psychometric properties and provided normative data of the Dutch Body Shape Questionnaire (BSQ34) and its shortened BSQ8C among patients with binge-eating disorder.

Methods: The two versions of the BSQ were administered to patients with binge-eating disorder (N = 155) enrolled for treatment, and to a community sample (N = 333). The translation and back-translation of the BSQ were performed by translators with and without eating-disorder expertise. Internal consistency, concurrent validity, test-retest reliability, incremental validity, and sensitivity to change were determined. A receiver-operating-characteristic curve-analysis was used to establish criterion-related validity, for which the Eating Disorder Examination-Shape concern subscale, was used. Uni-dimensionality of the instrument was investigated with confirmatory factor analysis. Norms (population-based T-scores and clinical percentile-scores) were determined.

Results: The psychometric properties of the BSQs were satisfactory. The BSQ34 discriminated well in body-shape dissatisfaction between patients with binge-eating disorder and the community sample (area-under-the-curve value = 0.91-0.98) and had a unidimensional factor structure. Comparing structural invariance between both samples revealed that scaler invariance was not supported, indicating that items may be interpreted differently by patients with binge-eating disorder and subjects from the community. Analyses were repeated for the BSQ8C, which yielded similar results.

Conclusion: The results indicated that both versions of the BSQ appeared suitable to screen for body-shape dissatisfaction among patients with binge-eating disorder. The BSQ34 supplies valuable information on the various types of concerns respondents have, which are critical to consider in clinical settings; the BSQ8C is recommended as a short screening tool.

Level of evidence: Level III: Evidence obtained from well-designed cohort or case-control analytic studies.

Purpose: This study aimed to develop and validate the Brief Eating Self-Efficacy Scale (ESEBS-BR) in Brazilian Portuguese, addressing the lack of tools to assess eating self-efficacy beliefs in Portuguese-speaking populations.

Method: The study sought to cross-culturally adapt the scale, evaluate its internal structure, validate its reliability and validity, and explore potential associations between eating self-efficacy and eating behaviors. The cross-cultural adaptation process involved translation and back-translation, expert committees, and pre-testing. Scale validation was conducted with 228 participants, including reliability analyses, confirmatory factor analysis, and correlations with established measures of eating behavior.

Results: The ESEBS-BR, maintaining all 8 original items, demonstrated high reliability, with a two-factor structure model confirmed by confirmatory factor analysis. Significant correlations were found between ESEBS-BR scores and measures of binge eating and eating behaviors, validating its criterion validity.

Conclusions: The development and validation of the ESEBS-BR represent a significant contribution to the assessment of eating self-efficacy in the Brazilian population. The scale proved to be sensitive, reliable, and valid, offering an important tool for research and clinical interventions related to eating behavior.

Level of evidence: V, descriptive cross-sectional study.

Background: Chronic kidney disease (CKD) is a major global health concern with increasing prevalence and associated complications. Obesity and obesity-related metabolic disorders have been linked to chronic kidney disease (CKD), although the evidence is still inconsistent. To investigate the relationship between different obesity phenotypes and the risk of CKD, we conducted a systematic review and meta-analysis.

Method: We conducted a comprehensive search of databases for all relevant studies up to February 2024, without imposing a specific start date, for observational studies assessing the relationship between obesity phenotypes and incident kidney dysfunction. We used fixed and random effects models for the meta-analysis, subgroup analyses were carried out to explore heterogeneity, and Egger's and Begg's tests were used to assess publication bias.

Result: This meta-analysis included 13 eligible observational studies with 492,829 participants. Pooling the studies regardless of the effect measure showed that individuals with metabolically unhealthy normal weight (MUNW) (ES = 1.58, 95% CI = 1.43-1.76), metabolically healthy obese (MHO) (ES = 1.20, 95% CI = 1.06-1.34), and metabolically unhealthy obese (MUO) (ES = 1.90, 95% CI = 1.63-2.20) phenotypes had a significantly increased risk for kidney dysfunction (KD) events. On the other hand, MUOW individuals did not significantly correlate with risk of CKD (ES = 1.63, 95% CI = 0.97-2.23) compared to the MHNW phenotype.

Conclusion: Healthy overweight and obese individuals had higher risk for the incident KD events; refuting the notion that metabolically healthy overweight and obese phenotypes are benign conditions.

Level of evidence: III Evidence obtained from well-designed cohort or cross-sectional studies.

Purpose: We provide the first systematic review and meta-analysis of research examining multidimensional perfectionism-perfectionistic strivings and perfectionistic concerns-and orthorexia.

Methods: The systematic review and meta-analysis was pre-registered and conducted using a search of PsycINFO, MEDLINE, Education Abstracts, and Oxford Academic, and ScienceDirect up to April 2023. PRISMA guidelines were also followed. Meta-analysis using random-effects models was used to derive independent and unique effects of perfectionism, as well as total unique effects (TUE), and relative weights. Moderation of effects were examined for age, gender, domain, perfectionism and orthorexia instruments, and methodological quality.

Results: Eighteen studies, including 19 samples (n = 7064), met the eligibility criteria with 12 of these studies (with 13 samples; n = 4984) providing sufficient information for meta-analysis. Meta-analysis revealed that perfectionistic strivings (r⁺  = 0.27, 95% CI [0.21, 0.32]) and perfectionistic concerns (r⁺  = 0.25, 95% CI [0.18, 0.31]) had positive relationships with orthorexia. After controlling for the relationship between perfectionism dimensions, only perfectionistic strivings predicted orthorexia which also contributed marginally more to an overall positive total unique effect of perfectionism (TUE = 0.35; 95% CI [0.28, 0.42]). There was tentative evidence that orthorexia instrument moderated the perfectionistic concerns-orthorexia relationship.

Discussion: Research has generally found that both dimensions of perfectionism are positively related to orthorexia. More high-quality research is needed to examine explanatory mechanisms while also gathering further evidence on differences in findings due to how orthorexia is measured, as well as other possible moderating factors.

Level of evidence: Level 1, systematic review and meta-analysis.

Background: Orthorexia is a complex phenomenon comprising distinct dimensions, including orthorexia nervosa (ON) and healthy orthorexia (HO). However, little is known about the factors influencing these dimensions, their disparities, and the psychological factors underlying orthorexia behaviours.

Objectives: This study aims to explore ON versus HO dimensions and the predictive role of adverse childhood experiences (ACEs) in a nationally representative sample of Polish individuals. In addition, we aim to investigate the mediating roles of alexithymia, embodiment, and experiential avoidance levels in this association.

Methods: A representative sample of Polish adults (n = 3557) participated in this study. Dimensions of orthorexia (HO, ON) were assessed using the Teruel Orthorexia Scale, while ACEs were evaluated using the Adverse Childhood Experiences Questionnaire. Levels of alexithymia were measured using the Toronto Alexithymia Scale, experiential avoidance through the Acceptance and Action Questionnaire, and embodiment intensity via the Experience of Embodiment Scale.

Results: Cluster analysis identified two distinctive orthorexia profiles in the whole sample, i.e., HO (n = 469) and ON (n = 1217), alongside three intermediate HO/ON profiles (n = 1871). The number of ACEs predicted ON tendencies as opposed to HO behaviours in participants. The mediating role of alexithymia, experiential avoidance, and embodiment in the association between ACEs and ON was also observed.

Conclusions: Our study suggests that orthorexia is a multidimensional eating style shaped by socio-cultural factors. Adverse childhood experiences may be related to ON behaviours by mediating psychological factors such as experiential avoidance, alexithymia, and embodiment. Effective education and collaborative support are necessary for addressing ON tendencies.

Introduction: Previous studies have focused on understanding the biopsychosocial implications of obesity stigma and have made proposals to minimize its negative consequences, as well as recommendations to eliminate or reduce this stigma; however, knowing which individuals stigmatize obesity and why will allow us to have a broader picture of stigmatization and thus help in planning interventions with greater impact.

Objective: The aims were to describe the stigmatization toward obesity in preadolescents and adolescents and to determine whether there are differences in body dissatisfaction, abnormal eating behaviors and self-esteem among those with and without stigma toward obesity.

Methods: A total of 307 preadolescents and 349 adolescents answered a set of questionnaires that evaluated abnormal eating behaviors, body dissatisfaction, self-esteem and stigma.

Results: Fifty-nine percent of the participants stigmatized individuals with obesity, with preadolescents having the greatest stigma levels. Differences were observed only in body dissatisfaction, where the group of preadolescents who stigmatized individuals with obesity and the group of adolescents who did not stigmatize individuals with obesity reported higher levels of body dissatisfaction.

Conclusion: Obesity is stigmatized at early ages, regardless of sex; however, preadolescents with stigma toward obesity and adolescents without stigma toward obesity have greater body dissatisfaction, indicating that body dissatisfaction plays a crucial role in the stigmatization of obesity.

Level of evidence: Level V, cross-sectional analytical study.

Objectives: The objective of this study was to evaluate the effectiveness of the combined use of empagliflozin (EMPA) and topiramate (TPM) versus a placebo in overweight/obese individuals without diabetes on a calorie-restricted diet.

Methods: In this study, 44 non-diabetic and overweight/obese subjects who were on a calorie restricted diet were randomly assigned into 2 groups: (1) Participants received a 10 mg EMPA tablet daily plus TPM tablet (at the 1st week 25 mg once a day and from the second week 25 mg twice a day); (2) Participants received an empagliflozin placebo (daily) plus a topiramate placebo (as mentioned for topiramate tablet in group 1), for 12 weeks. At baseline and weeks 4, 8, 12, weight, height, body mass index (BMI), waist circumference (WC), and body composition were evaluated. Before and after the intervention, blood pressure, C reactive protein, and glucose and lipid profile parameters were measured.

Results: The EMPA/TPM group, compared to placebo, had a greater percent change of weight at week 12 (- 8.92 ± 1.80 vs. - 4.93 ± 1.17). The intervention group had a greater percent change of fat mass and fat percent at week 12 (P < 0.05). However, there was no difference in the percent of change in fat-free percent between the two groups at week 12 (P = 0.577). Within-group analysis found a significant reduction in SBP, DBP, FBS, insulin, HOMA-IR, TC, LDL, HDL, TG, and CRP in both groups (P < 0.05). At week 12, no statistically significant difference was observed between the two groups in any of mentioned variables (P > 0.05).

Conclusion: In non-diabetic overweight/obese individuals, the combination of EMPA/TPM and calorie restriction led to a notable decrease in body weight and was generally well-tolerated. Further research is required to evaluate the potential advantages of utilizing this combination for sustained weight management in the long run.

Level i: Randomized clinical trial.

Purpose: Developing personal goals beyond weight and shape, and promoting the agency to pursue those goals, could aid in treatment and recovery from anorexia nervosa (AN). This research explores the strengths, interests and goals of individuals currently receiving treatment for AN and evaluates how treatment services are supporting them to work towards personal goals across all areas of everyday life.

Method: A total of 58 community-dwelling adults currently receiving treatment for anorexia nervosa at any stage of recovery completed the Client Assessment of Strengths, Interests and Goals Self-Report (CASIG-SR). Participants reported their goals for accommodation, work and study, interpersonal relationships, recreational activities, spirituality, religion or life purpose, physical health and mental health, and the personal strengths and supports needed to achieve those goals. Concordance scores were calculated between importance of personal goals and level of support from current services regarding these goals.

Results: Themes identified across goals, strengths and supports were Connection, Independence & Confidence, Meaning & Self: The Real Me, and Stability & Balance. Work and study goals and strengths were identified strongly. The key support needed was stability from the current treatment team to provide a stable base for change. Concordance scores indicate support provided for personal goals was less than the importance of the goal to the individual.

Conclusion: Results suggest goals for everyday living are critical to recovery in anorexia nervosa. Specific clinical considerations to increase motivation and hope are increased access to peer support, a focus on increasing positive affect, supporting safe exercise and promoting outdoor experiences and connection with nature.

Level iii: Evidence obtained from well-designed cohort or case-control analytic studies.