Missed and Delayed Diagnoses of Acute Human Immunodeficiency Virus (HIV) Infection in a Southern Opt-Out HIV Testing Environment Without Reflex HIV RNA Testing.

IF 3.8 4区 医学 Q2 IMMUNOLOGY Open Forum Infectious Diseases Pub Date : 2025-01-17 eCollection Date: 2025-01-01 DOI:10.1093/ofid/ofae684
Sarah F Gruber, Eli P Wilber, Brittany Smith, Paulina A Rebolledo, Jonathan A Colasanti, Rishika Iytha, Megan Schwinne, Chad Robichaux, Meredith H Lora
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Abstract

Prompt confirmation of human immunodeficiency virus (HIV) is critical. We examined 10 years of discordant results without reflex HIV RNA. Of patients with acute HIV infection, 43.9% (95% confidence interval, 36.2%-52.0%) had confirmation delays >30 days or were never confirmed, indicating a need for reflex RNA to facilitate diagnosis.

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在没有反射性HIV RNA检测的南方HIV检测环境中,急性人类免疫缺陷病毒(HIV)感染的漏诊和延迟诊断
及时确认人类免疫缺陷病毒(HIV)至关重要。我们检查了10年来没有反射性HIV RNA的不一致结果。在急性HIV感染患者中,43.9%(95%置信区间36.2%-52.0%)的确诊延迟了30天或从未确诊,这表明需要反射RNA来促进诊断。
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来源期刊
Open Forum Infectious Diseases
Open Forum Infectious Diseases Medicine-Neurology (clinical)
CiteScore
6.70
自引率
4.80%
发文量
630
审稿时长
9 weeks
期刊介绍: Open Forum Infectious Diseases provides a global forum for the publication of clinical, translational, and basic research findings in a fully open access, online journal environment. The journal reflects the broad diversity of the field of infectious diseases, and focuses on the intersection of biomedical science and clinical practice, with a particular emphasis on knowledge that holds the potential to improve patient care in populations around the world. Fully peer-reviewed, OFID supports the international community of infectious diseases experts by providing a venue for articles that further the understanding of all aspects of infectious diseases.
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