VGX: VGG19-Based Gradient Explainer Interpretable Architecture for Brain Tumor Detection in Microscopy Magnetic Resonance Imaging (MMRI).

IF 2 3区 工程技术 Q2 ANATOMY & MORPHOLOGY Microscopy Research and Technique Pub Date : 2025-01-17 DOI:10.1002/jemt.24809
Deep Kothadiya, Amjad Rehman, Bayan AlGhofaily, Chintan Bhatt, Noor Ayesha, Tanzila Saba
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Abstract

The development of deep learning algorithms has transformed medical image analysis, especially in brain tumor recognition. This research introduces a robust automatic microbrain tumor identification method utilizing the VGG16 deep learning model. Microscopy magnetic resonance imaging (MMRI) scans extract detailed features, providing multi-modal insights. VGG16, known for its depth and high performance, is utilized for this purpose. The study demonstrates the model's potential for precise and effective diagnosis by examining how well it can differentiate between areas of normal brain tissue and cancerous regions, leveraging both MRI and microscopy data. We describe in full the pre-processing actions taken to improve the quality of input data and maximize model efficiency. A carefully selected dataset, incorporating diverse tumor sizes and types from both microscopy and MRI sources, is used during the training phase to ensure representativeness. The proposed modified VGG19 model achieved 98.81% validation accuracy. Despite good accuracy, interpretation of the result still questionable. The proposed methodology integrates explainable AI (XAI) for brain tumor detection to interpret system decisions. The proposed study uses a gradient explainer to interpret classification results. Comparative statistical analysis highlights the effectiveness of the proposed explainer model over other XAI techniques.

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基于vgg19的梯度解释器可解释架构在显微磁共振成像(MMRI)中检测脑肿瘤。
深度学习算法的发展已经改变了医学图像分析,特别是在脑肿瘤识别方面。本研究引入了一种基于VGG16深度学习模型的鲁棒自动小脑肿瘤识别方法。显微镜磁共振成像(MMRI)扫描提取详细的特征,提供多模式的见解。VGG16以其深度和高性能而闻名,用于此目的。该研究通过检查该模型如何区分正常脑组织区域和癌变区域,利用MRI和显微镜数据,证明了该模型在精确有效诊断方面的潜力。我们全面描述了为提高输入数据质量和最大化模型效率而采取的预处理行动。在训练阶段使用精心挑选的数据集,包括来自显微镜和MRI来源的不同肿瘤大小和类型,以确保代表性。改进后的VGG19模型验证准确率达到98.81%。尽管准确度很高,但对结果的解释仍有疑问。提出的方法集成了用于脑肿瘤检测的可解释人工智能(XAI)来解释系统决策。提出的研究使用梯度解释器来解释分类结果。对比统计分析强调了所提出的解释器模型优于其他XAI技术的有效性。
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来源期刊
Microscopy Research and Technique
Microscopy Research and Technique 医学-解剖学与形态学
CiteScore
5.30
自引率
20.00%
发文量
233
审稿时长
4.7 months
期刊介绍: Microscopy Research and Technique (MRT) publishes articles on all aspects of advanced microscopy original architecture and methodologies with applications in the biological, clinical, chemical, and materials sciences. Original basic and applied research as well as technical papers dealing with the various subsets of microscopy are encouraged. MRT is the right form for those developing new microscopy methods or using the microscope to answer key questions in basic and applied research.
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