Hong Wang, Yujing Li, Songying Shen, Xin Li, Changhe Li, Yihao Li, Huimin Chen, Caihong Ren, Yinsen Song, Yao Tang, Huijun Dong, Meng Zhao, Sisen Zhang, Hongyu Wang
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引用次数: 0
Abstract
Hyperbaric oxygen has been used to treat many diseases. However, there are few reports on hyperbaric oxygen treatment for paroxysmal sympathetic hyperactivity at home and abroad, and the clinical experience is very limited. To understand the efficacy of hyperbaric oxygen treatment for paroxysmal sympathetic hyperactivity after brain injury, this retrospective study was conducted in the adult intensive care units of five medical centers in central China. Ninety-two patients with paroxysmal sympathetic hyperactivity syndrome after brain injury were selected from January 2021 to September 2023. Fifty-six patients treated with hyperbaric oxygen were included in the hyperbaric oxygen group, and 36 patients without hyperbaric oxygen treatment were included in the control group. Patients in the hyperbaric oxygen group received 3-5 courses of hyperbaric oxygen treatment, twice daily, once for 70 minutes, 10 days for 1 course of treatment. Compared with before hyperbaric oxygen treatment, the paroxysmal sympathetic hyperactivity symptoms of all patients were significantly relieved after three courses of hyperbaric oxygen treatment. Compared with those in the control group, patients in the hyperbaric oxygen group had higher Glasgow coma scale scores, lower paroxysmal sympathetic hyperactivity syndrome assessment measure scores, and shorter intensive care unit stays. In conclusion, the use of hyperbaric oxygen therapy as an assisted therapy can significantly alleviate the symptoms of patients with paroxysmal sympathetic hyperactivity, thereby providing new ideas for the treatment of paroxysmal sympathetic hyperactivity.
期刊介绍：
Medical Gas Research is an open access journal which publishes basic, translational, and clinical research focusing on the neurobiology as well as multidisciplinary aspects of medical gas research and their applications to related disorders. The journal covers all areas of medical gas research, but also has several special sections. Authors can submit directly to these sections, whose peer-review process is overseen by our distinguished Section Editors: Inert gases - Edited by Xuejun Sun and Mark Coburn, Gasotransmitters - Edited by Atsunori Nakao and John Calvert, Oxygen and diving medicine - Edited by Daniel Rossignol and Ke Jian Liu, Anesthetic gases - Edited by Richard Applegate and Zhongcong Xie, Medical gas in other fields of biology - Edited by John Zhang. Medical gas is a large family including oxygen, hydrogen, carbon monoxide, carbon dioxide, nitrogen, xenon, hydrogen sulfide, nitrous oxide, carbon disulfide, argon, helium and other noble gases. These medical gases are used in multiple fields of clinical practice and basic science research including anesthesiology, hyperbaric oxygen medicine, diving medicine, internal medicine, emergency medicine, surgery, and many basic sciences disciplines such as physiology, pharmacology, biochemistry, microbiology and neurosciences. Due to the unique nature of medical gas practice, Medical Gas Research will serve as an information platform for educational and technological advances in the field of medical gas.
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