Indicators associated with severity and mortality in hospitalized people with HIV: A retrospective cohort.

IF 1.2 Q3 NURSING Revista Brasileira De Enfermagem Pub Date : 2025-01-13 eCollection Date: 2025-01-01 DOI:10.1590/0034-7167-2024-0204

Jarbas da Silva Ziani, Jenifer Härter, Francielle Liz Monteiro, Camila Biazus Dalcin, Stela Maris de Mello Padoin, Marcelo Ribeiro Primeira, Laís Mara Caetano da Silva Corcini, Cláudia Zamberlan

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Abstract

Objectives: to compare the sociodemographic and clinical severity indicators of hospitalized people with HIV in relation to clinical outcomes and urgent hospital admission.

Methods: a retrospective cohort study was conducted with 102 medical records of HIV-infected individuals hospitalized in a hospital in southern Brazil. In addition to descriptive analysis, Fisher's exact test, Pearson's Chi-square, and logistic regression were used.

Results: the data showed a significant direct effect on severity indicators in the following variables: male sex (p=0.013), skin color (p=0.023), level of education (p=0.000), urgent admissions (p=0.000), late diagnosis (p=0.001), diabetes mellitus (p=0.001), hypertension (p=0.004), kidney disease (p=0.002), high viral load (p=0.006), CD4+ count below 200 (p=0.005), fever (p=0.016), weight loss (p=0.013), co-infection with hepatitis C (p=0.004), and mortality (p=0.007).

Conclusions: three sociodemographic and thirteen clinical markers were identified as being associated with the risk of clinical deterioration in hospitalized people with HIV.

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与住院HIV感染者严重程度和死亡率相关的指标：一项回顾性队列

目的：比较艾滋病毒住院患者的社会人口学和临床严重程度指标与临床结果和紧急住院的关系。方法：对巴西南部一家医院102例hiv感染者的医疗记录进行回顾性队列研究。除描述性分析外，还使用Fisher精确检验、Pearson卡方检验和逻辑回归。结果：男性（p=0.013）、肤色（p=0.023）、文化程度（p=0.000）、紧急入院（p=0.000）、晚期诊断（p=0.001）、糖尿病（p=0.001）、高血压（p=0.004）、肾病（p=0.002）、病毒载量高（p=0.006）、CD4+计数低于200 （p=0.005）、发热（p=0.016）、体重减轻（p=0.013）、合并丙型肝炎感染（p=0.004）、死亡率（p=0.007）等严重程度指标有直接影响。结论：3个社会人口学指标和13个临床指标被确定为与住院HIV感染者临床恶化风险相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Revista Brasileira De Enfermagem NURSING-

CiteScore

2.30

自引率

7.70%

发文量

477

审稿时长

21 weeks

期刊介绍： The Revista Brasileira de Enfermagem created in 1932, March 20 is the official publication of the Associação Brasileira de Enfermagem (Brazilian Nursing Association) has as purpose to disseminate the scientific production from different nursing interest areas of knowledge, including those which express the political project of the Association. The Revista Brasileira de Enfermagem is the oldest journal of the Brazilian nursing. Its first title was "Annaes de Enfermagem" from 1932 to 1941, being entitled Anais de Enfermagem" until 1955, when its title was changed to the current.

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