Comprehensive bibliometric analysis of pharmacotherapy for bipolar disorders: Present trends and future directions.

IF 3.9 4区 医学 Q1 PSYCHIATRY World Journal of Psychiatry Pub Date : 2025-01-19 DOI:10.5498/wjp.v15.i1.100685
Bo-Fan Chen, Li Liu, Fang-Zhen Lin, Hai-Min Zeng, Hai-Qiang Huang, Chun-Fang Zhang, Cong-Cong Liu, Xiang Chen, Jie Peng, Yun-Fa Wang, Zhi-Lin Wang, Bin Chen, De-Le Liu, Yun Liu, Zheng-Zheng Li, Xin-Xing Zeng
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Abstract

Background: Bipolar disorder (BD) is a severe mental illness characterized by significant mood swings. Effective drug treatment modalities are crucial for managing BD.

Aim: To analyze the current status and future trends of global research on BD drug treatment over the last decade.

Methods: The Web of Science Core Collection database spanning from 2015 to 2024 was utilized to retrieve literature related to BD drug treatment. A total of 2624 articles were extracted. Data visualization and analysis were conducted using CiteSpace, VOSviewer, Pajek, Scimago Graphica, and R-studio bibliometrix to identify research hotspots, key contributors, and future trends.

Results: The United States, China, and the United Kingdom have made the most significant contributions to research on BD drug treatment and formed notable research collaboration networks. The University of Pittsburgh, Massachusetts General Hospital, and the University of Michigan have been identified as the major research institutions in this field. The Journal of Affective Disorders is the most influential journal. A keyword analysis revealed research hotspots related to clinical symptoms, drug efficacy, and genetic mechanisms. A citation analysis identified the management guidelines published by Yatham et al in 2018 as the most cited paper.

Conclusion: This study provides a detailed overview of the field of BD drug treatment, highlighting key contributors, research hotspots, and future directions. The study findings can be employed as a reference for future research and policymaking, which may enable further development and optimization of BD pharmacotherapy.

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双相情感障碍药物治疗的综合文献计量学分析:当前趋势和未来方向。
背景:双相情感障碍(BD)是一种以显著情绪波动为特征的严重精神疾病。有效的药物治疗方式是治疗双相障碍的关键。目的:分析近十年来全球双相障碍药物治疗研究的现状及未来趋势。方法:利用Web of Science Core Collection数据库2015 - 2024年检索双相障碍药物治疗相关文献。共提取2624篇文章。利用CiteSpace、VOSviewer、Pajek、Scimago Graphica和R-studio bibliometrix等工具对数据进行可视化分析,确定研究热点、关键贡献者和未来趋势。结果:美国、中国和英国对双相障碍药物治疗的研究贡献最大,形成了显著的研究合作网络。匹兹堡大学、马萨诸塞州总医院和密歇根大学已被确定为该领域的主要研究机构。《情感障碍杂志》是最有影响力的杂志。关键词分析揭示了临床症状、药物疗效、遗传机制等方面的研究热点。引用分析发现,Yatham等人在2018年发表的管理指南是被引用最多的论文。结论:本研究对双相障碍药物治疗领域进行了详细的概述,突出了关键贡献者、研究热点和未来发展方向。研究结果可为今后的研究和政策制定提供参考,为BD药物治疗的进一步发展和优化提供参考。
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期刊介绍: The World Journal of Psychiatry (WJP) is a high-quality, peer reviewed, open-access journal. The primary task of WJP is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of psychiatry. In order to promote productive academic communication, the peer review process for the WJP is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJP are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in psychiatry.
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