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Global research status and trends of somatic symptom disorder: A bibliometric study. 躯体症状障碍的全球研究现状与趋势:文献计量学研究。
IF 3.9 4区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-19 DOI: 10.5498/wjp.v15.i1.100730
Chao Yang, Kun Zhang, Qian Wang, Shuai Wang, Huan Li, Kai Zhang

Background: With the growing scholarly and clinical fascination with somatic symptom disorder (SSD), a bibliometric analysis is lacking.

Aim: To conduct a bibliometric analysis to investigate the current status and frontiers of SSD.

Methods: The documents related to SSD are obtained from the web of science core collection database (WoSCC), and VOSviewer 1.6.16 from January 1, 2000 to December 31, 2023, and the WoSCC's literature analysis wire were used to conduct the bibliometric analysis.

Results: A total of 567 documents related to SSD were included, and 2325 authors across 947 institutions from 57 countries/regions have contributed to SSD research, published in 277 journals. The most productive author, institution, country and journal were Löwe B, University of Hamburg, Germany, and Journal of Psychosomatic Research respectively. The first high-cited document was published in the Journal of Psychosomatic Research in 2013 by Dimsdale JE and colleagues, which explored the rationale behind the SSD diagnosis introduction in diagnostic and statistical manual of mental disorders.

Conclusion: In conclusion, the main research hotspots and frontiers in the field of SSD are validity and reliability of the SSD criteria, functional impairment of SSD, and the treatment for SSD. More high-quality studies are needed to assess the diagnosis and treatment of SSD.

背景:随着越来越多的学术和临床对躯体症状障碍(SSD)的迷恋,文献计量分析是缺乏的。目的:通过文献计量学分析,探讨固态硬盘的研究现状和前沿。方法:从web of science core collection database (WoSCC)中获取2000年1月1日至2023年12月31日期间与SSD相关的文献,使用WoSCC的文献分析线进行文献计量学分析。结果:共纳入SSD相关文献567篇,来自57个国家/地区的947家机构的2325位作者在277种期刊上发表了SSD相关研究成果。最高产的作者、机构、国家和期刊分别是Löwe B,德国汉堡大学和journal of Psychosomatic Research。2013年,Dimsdale JE及其同事在《身心研究杂志》(Journal of Psychosomatic Research)上发表了第一篇高被引文献,探讨了在精神障碍诊断与统计手册中引入SSD诊断的基本原理。结论:综上所述,SSD领域的主要研究热点和前沿是SSD标准的有效性和可靠性、SSD的功能损伤以及SSD的治疗。需要更多高质量的研究来评估SSD的诊断和治疗。
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引用次数: 0
Correlation between anxiety, depression, and social stress in young patients with thoracolumbar spine fractures. 年轻胸腰椎骨折患者焦虑、抑郁和社会压力的相关性研究
IF 3.9 4区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-19 DOI: 10.5498/wjp.v15.i1.101373
Bo Wang, Da Shi, Yin-Di Sun, Bo Dong
<p><strong>Background: </strong>Traumatic injuries, such as falling, car accidents, and crushing mostly cause spinal fractures in young and middle-aged people, and > 50% of them are thoracolumbar fractures. This kind of fracture is easily combined with serious injuries to peripheral nerves and soft tissues, which causes paralysis of the lower limbs if there is no timely rehabilitation treatment. Young patients with thoracolumbar fractures find it difficult to recover after the operation, and they are prone to depression, low self-esteem, and other negative emotions.</p><p><strong>Aim: </strong>To investigate the association between anxiety, depression, and social stress in young patients with thoracolumbar spine fractures and the effect on rehabilitation outcomes.</p><p><strong>Methods: </strong>This study retrospectively analyzed 100 patients admitted to the orthopedic department of Honghui Hospital, Xi'an Jiaotong University who underwent thoracolumbar spine fracture surgery from January 2022 to June 2023. The general data of the patients were assessed with the Hamilton anxiety scale (HAMA), Hamilton depression scale (HAMD), life events scale, and social support rating scale (SSRS) to identify the correlation between anxiety, depression scores, and social stress and social support. The Japanese Orthopedic Association (JOA) was utilized to evaluate the rehabilitation outcomes of the patients and to analyze the effects of anxiety and depression scores on rehabilitation.</p><p><strong>Results: </strong>According to the scores of HAMD and HAMA in all patients, the prevalence of depression in patients was 39% (39/100), and the prevalence of anxiety was 49% (49/100). Patients were categorized into non-depression (<i>n</i> = 61) and depression (<i>n</i> = 39), non-anxiety (<i>n</i> = 51), and anxiety (<i>n</i> = 49) groups. Statistically significant differences in gender, occupation, Pittsburgh Sleep Quality Index (PSQI) score, and monthly family income were observed between the non-depression and depression groups (<i>P</i> < 0.05). A significant difference in occupation and PSQI score was found between the non-anxiety and anxiety groups. Both depression (<i>r</i> = 0.207, <i>P</i> = 0.038) and anxiety scores (<i>r</i> = 0.473, <i>P</i> < 0.001) were significantly and positively correlated with negative life events. The difference in negative life event scores as well as SSRS total and item scores was statistically significant between patients in the non-depression and depression groups (<i>P</i> < 0.05). The difference between the non-anxiety and anxiety groups was statistically significant (<i>P</i> < 0.05) in the negative life event scores as well as the total SSRS scores. Additionally, JOA scores were significantly lower in both anxious and depressed patients.</p><p><strong>Conclusion: </strong>Young patients with thoracolumbar fractures are prone to anxiety and depression. Patients' anxiety and depression are closely associated with social press
背景:中青年脊柱骨折多由外伤引起,如坠落、车祸、碾压等,其中胸腰椎骨折占50%。这种骨折容易合并周围神经和软组织的严重损伤,如不及时进行康复治疗,极易造成下肢瘫痪。年轻胸腰椎骨折患者术后难以恢复,易出现抑郁、自卑等负面情绪。目的:探讨年轻胸腰椎骨折患者焦虑、抑郁和社会压力的关系及其对康复预后的影响。方法:回顾性分析西安交通大学弘汇医院骨科2022年1月至2023年6月收治的100例胸腰椎骨折患者。采用汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)、生活事件量表(life events scale)和社会支持评定量表(SSRS)对患者的一般资料进行评估,以确定焦虑、抑郁评分与社会压力和社会支持的相关性。采用日本骨科协会(JOA)评估患者的康复效果,分析焦虑和抑郁评分对康复的影响。结果:根据所有患者的HAMD和HAMA评分,患者抑郁患病率为39%(39/100),焦虑患病率为49%(49/100)。患者分为非抑郁组(n = 61)、抑郁组(n = 39)、非焦虑组(n = 51)和焦虑组(n = 49)。非抑郁组与抑郁组在性别、职业、匹兹堡睡眠质量指数(PSQI)评分、家庭月收入等方面差异均有统计学意义(P < 0.05)。非焦虑组和焦虑组在职业和PSQI得分上存在显著差异。抑郁得分(r = 0.207, P = 0.038)和焦虑得分(r = 0.473, P < 0.001)与负性生活事件均呈显著正相关。非抑郁组与抑郁组患者负性生活事件得分、SSRS总分、单项得分差异均有统计学意义(P < 0.05)。非焦虑组与焦虑组负性生活事件得分及SSRS总分差异均有统计学意义(P < 0.05)。此外,焦虑和抑郁患者的JOA得分都明显较低。结论:年轻胸腰椎骨折患者易出现焦虑和抑郁。患者焦虑抑郁与社会压力密切相关,降低青年胸腰椎骨折患者的生活压力,增强社会支持,改善焦虑抑郁心理。,影响患者的康复。
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引用次数: 0
Development and prospect of near-infrared spectroscopy-assisted schizophrenia diagnosis based on bibliometrics. 基于文献计量学的近红外光谱辅助精神分裂症诊断的发展与展望。
IF 3.9 4区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-19 DOI: 10.5498/wjp.v15.i1.100791
Yan Zhang, Hao-Yu Xing, Juan Yan

In this editorial, we comment on the recent article by Fei et al exploring the field of near-infrared spectroscopy (NIRS) research in schizophrenia from a bibliometrics perspective. In recent years, NIRS has shown unique advantages in the auxiliary diagnosis of schizophrenia, and the introduction of bibliometrics has provided a macro perspective for research in this field. Despite the opportunities brought about by these technological developments, remaining challenges require multidisciplinary approach to devise a reliable and accurate diagnosis system for schizophrenia. Nonetheless, NIRS-assisted technology is expected to contribute to the division of methods for early intervention and treatment of schizophrenia.

在这篇社论中,我们对Fei等人最近从文献计量学角度探索精神分裂症近红外光谱(NIRS)研究领域的文章进行了评论。近年来,近红外光谱在精神分裂症的辅助诊断中显示出独特的优势,文献计量学的引入为该领域的研究提供了宏观视角。尽管这些技术发展带来了机遇,但仍然存在挑战,需要多学科方法来设计一种可靠和准确的精神分裂症诊断系统。尽管如此,nirs辅助技术有望为精神分裂症的早期干预和治疗方法的划分做出贡献。
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引用次数: 0
Motivational interviewing in postoperative rehabilitation and chronic disease management: Current findings and future research directions. 动机访谈在术后康复和慢性疾病管理中的应用:目前的发现和未来的研究方向。
IF 3.9 4区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-19 DOI: 10.5498/wjp.v15.i1.102737
Bing-Ren Zhang, Xiao Yang

This editorial highlights a recently published study examining the effectiveness of music therapy combined with motivational interviewing (MI) in addressing anxiety and depression among young and middle-aged patients following percutaneous coronary intervention. It further explores existing evidence and potential future research directions for MI in postoperative rehabilitation and chronic disease management. MI aims to facilitate behavioral change and promote healthier lifestyles by fostering a trusting relationship with patients and enhancing intrinsic motivation. Research has demonstrated its effectiveness in postoperative recovery for oncological surgery, stroke, organ transplants, and gastrointestinal procedures, as well as in managing chronic conditions such as diabetes, obesity, and periodontal disease. The approach is patient-centered, adaptable, cost-effective, and easily replicable, though its limitations include reliance on the therapist's expertise, variability in individual responses, and insufficient long-term follow-up studies. Future research could focus on developing individualized and precise intervention models, exploring applications in digital health management, and confirming long-term outcomes to provide more comprehensive support for patient rehabilitation.

这篇社论强调了最近发表的一项研究,该研究考察了音乐疗法结合动机访谈(MI)在解决经皮冠状动脉介入治疗后中青年患者焦虑和抑郁方面的有效性。进一步探讨心肌梗死在术后康复和慢性疾病管理中的现有证据和潜在的未来研究方向。MI旨在通过与患者建立信任关系和增强内在动机来促进行为改变和促进更健康的生活方式。研究已经证明了它在肿瘤手术、中风、器官移植和胃肠道手术的术后恢复以及糖尿病、肥胖和牙周病等慢性疾病的治疗方面的有效性。该方法以患者为中心,适应性强,成本效益高,易于复制,尽管其局限性包括依赖治疗师的专业知识,个体反应的可变性,以及长期随访研究的不足。未来的研究可侧重于开发个性化、精准化的干预模式,探索在数字化健康管理中的应用,确定远期效果,为患者康复提供更全面的支持。
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引用次数: 0
Negative efficacy of antidepressants in pharmacotherapy of child and adolescent depression. 抗抑郁药物治疗儿童青少年抑郁症的负性疗效观察。
IF 3.9 4区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-19 DOI: 10.5498/wjp.v15.i1.100308
Min Xu, Hai-Ying Jin, Feng-Li Sun, Wei-Dong Jin

Antidepressants are the main drugs used to treat depression, but they have not been shown to be effective in the treatment of child and adolescent depression. However, many adolescent depression treatment guidelines still recommend the use of antidepressants, especially specific serotonin re-uptake inhibitors. Previous studies have suggested that antidepressants have little therapeutic effect but many side effects, such as switching to mania, suicide, and non-suicidal self injury (NSSI), in the treatment of child and adolescent depression. In the process of developing guidelines, drug recommendations should not only focus on improving symptoms, but they should also consider potential side effects. This review discusses the serious side effects of antidepressants, including switching to mania, suicide, and NSSI.

抗抑郁药是治疗抑郁症的主要药物,但它们在治疗儿童和青少年抑郁症方面尚未被证明有效。然而,许多青少年抑郁症治疗指南仍然推荐使用抗抑郁药,特别是特定的5 -羟色胺再摄取抑制剂。以往的研究表明,抗抑郁药物在治疗儿童和青少年抑郁症时疗效甚微,但有许多副作用,如转向躁狂、自杀和非自杀性自伤(NSSI)。在制定指南的过程中,药物建议不仅应该关注改善症状,还应该考虑潜在的副作用。这篇综述讨论了抗抑郁药的严重副作用,包括转向躁狂、自杀和自伤。
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引用次数: 0
Perceptions and emotions in postoperative recovery of patients with perianal diseases. 感知与情绪在肛周疾病患者术后恢复中的作用。
IF 3.9 4区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-19 DOI: 10.5498/wjp.v15.i1.101563
Bryan Adrian Priego-Parra, Jose Maria Remes-Troche

This article examines the complex relationship between disease perception, negative emotions, and their impact on postoperative recovery in patients with perianal diseases. These conditions not only cause physical discomfort, but also carry a significant emotional burden, often exacerbated by social stigma. Psychological factors, including stress, anxiety, and depression, activate neuroendocrine pathways, such as the hypothalamic-pituitary-adrenal axis, disrupting the gut microbiota and leading to dysbiosis. This disruption can delay wound healing, prolong hospital stay, and intensify pain. Drawing on the findings of Hou et al, our article highlights the critical role of illness perception and negative emotions in shaping recovery outcomes. It advocates for a holistic approach that integrates psychological support and gut microbiota modulation, to enhance healing and improve overall patient outcomes.

本文探讨疾病感知、负面情绪及其对肛周疾病患者术后恢复的影响之间的复杂关系。这些疾病不仅会导致身体不适,还会带来沉重的情感负担,而社会耻辱感往往会加剧这种负担。心理因素,包括压力、焦虑和抑郁,激活神经内分泌通路,如下丘脑-垂体-肾上腺轴,破坏肠道微生物群,导致生态失调。这种破坏会延迟伤口愈合,延长住院时间,并加剧疼痛。根据侯等人的研究结果,我们的文章强调了疾病感知和负面情绪在塑造康复结果中的关键作用。它提倡一种综合心理支持和肠道菌群调节的整体方法,以增强愈合和改善患者的整体结果。
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引用次数: 0
Association of stent thrombectomy and conventional treatment with neuroprotection, complications, anxiety, and depression in acute ischemic stroke patients. 急性缺血性脑卒中患者支架取栓与常规治疗与神经保护、并发症、焦虑和抑郁的关系
IF 3.9 4区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-19 DOI: 10.5498/wjp.v15.i1.101182
Kai-Jie Yang, Jia-Jian Huang, Cai-Xia Xuan

Background: Acute ischemic stroke (AIS) is an abrupt blood flow cessation to a specific brain region within a vascular zone, causing a subsequent decline in neurological capabilities. Stent thrombectomy is a recently established technique for treating AIS. It provides the benefits of being a relatively simple and safe procedure, capable of partially enhancing a patient's condition. However, some patients may experience endothelial damage and recurrent thrombosis, with clinical outcomes that are not always satisfactory. Hence, the efficacy of this method remains unclear.

Aim: To survey the association of stent thrombectomy vs standard treatment with neurological function protection, complications, and short-term prognosis in patients diagnosed with AIS.

Methods: This study assigned 90 patients with AIS to the observation and control groups (n = 45 patients) from December 2020 to December 2022. Stent thrombectomy was conducted in the observation group, whereas routine treatment was provided to the control group. The study assessed the therapeutic outcomes of two groups, including a comparison of their neurological function, living ability, anxiety and depression status, plaque area, serum inflammatory factors, serum Smur100 β protein, neuron-specific enolase (NSE), homocysteine (Hcy), and vascular endothelial function. Additionally, the incidence of complications was calculated and analyzed for each group.

Results: The total effective rate of treatment was 77.78% and 95.56% in the control and observation groups, respectively. After 8 weeks of treatment, the scores on the National Institutes of Health Stroke Scale, Hamilton Anxiety Scale, and Hamilton Depression Scale decreased remarkably; the Barthel index increased remarkably, with better improvement effects of the scores in the observation group (P < 0.05); total cholesterol, triglyceride, C-reactive protein, and plaque area lessened remarkably, with fewer patients in the observation group (P < 0.05); S-100β protein, NSE, and Hcy levels lessened remarkably, with fewer patients in the observation group (P < 0.05); serum vascular endothelial growth factor and nitric oxide synthase levels increased remarkably, whereas the endothelin-1 level decreased, with better improvement effect in the observation group (P < 0.05). Complications occurred in 8.88% of patients in the observation group compared with 33.33% in the control group.

Conclusion: Stent thrombectomy appeared to provide more remarkable neuroprotective effects in patients with AIS compared to the intravenous thrombolysis regimen. Additionally, it has effectively improved the neurological function, daily activities, and vascular endothelial function of patients, while reducing the incidence of complications and improving short-term prognosis.

背景:急性缺血性脑卒中(Acute ischemic stroke, AIS)是一种血管区内特定脑区域的血液流动突然停止,导致随后的神经功能下降。支架取栓术是一种新近建立的治疗AIS的技术。它提供了一个相对简单和安全的程序的好处,能够部分改善病人的状况。然而,一些患者可能会出现内皮损伤和复发性血栓形成,其临床结果并不总是令人满意。因此,这种方法的功效尚不清楚。目的:探讨AIS患者支架取栓与标准治疗与神经功能保护、并发症和短期预后的关系。方法:本研究于2020年12月至2022年12月将90例AIS患者分为观察组和对照组(n = 45例)。观察组采用支架取栓术,对照组采用常规治疗。该研究评估了两组患者的治疗结果,包括比较他们的神经功能、生活能力、焦虑和抑郁状态、斑块面积、血清炎症因子、血清Smur100 β蛋白、神经元特异性烯醇化酶(NSE)、同型半胱氨酸(Hcy)和血管内皮功能。计算并分析各组的并发症发生率。结果:对照组和观察组总有效率分别为77.78%和95.56%。治疗8周后,美国国立卫生研究院卒中量表、汉密尔顿焦虑量表、汉密尔顿抑郁量表得分均显著下降;Barthel指数显著升高,观察组评分改善效果更好(P < 0.05);总胆固醇、甘油三酯、c反应蛋白、斑块面积明显降低,且观察组患者较少(P < 0.05);S-100β蛋白、NSE、Hcy水平显著降低,且观察组患者较少(P < 0.05);血清血管内皮生长因子和一氧化氮合酶水平显著升高,内皮素-1水平显著降低,观察组改善效果较好(P < 0.05)。观察组患者并发症发生率为8.88%,对照组为33.33%。结论:与静脉溶栓方案相比,支架取栓对AIS患者的神经保护作用更为显著。有效改善患者的神经功能、日常活动、血管内皮功能,减少并发症的发生,改善短期预后。
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引用次数: 0
Clinical value of combining epirubicin with mindfulness intervention in patients with urinary system tumors and depression. 表柔比星联合正念干预泌尿系统肿瘤伴抑郁患者的临床价值。
IF 3.9 4区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-19 DOI: 10.5498/wjp.v15.i1.98737
Juan Liu, Yan-Ping Guo, Yan-Mei Lu, Bei-Lin Wang

Background: Urinary system tumors often cause negative psychological symptoms, such as depression and dysphoria which significantly impact immune function and indirectly affect cancer prognosis. While epirubicin (EPI) is recommended by the European Association of Urology and can improve prognosis, its long-term use can cause toxic side effects, reduce treatment compliance, and increase psychological burden. Therefore, an appropriate intervention mode is necessary.

Aim: To explore the clinical value of EPI combined with mindfulness intervention in patients with urinary system tumors and depression.

Methods: This was a retrospective study including 110 patients with urinary system tumors and depression admitted to Zhumadian Central Hospital between March 2021 and July 2023. Patients were divided into conventional (n = 55) and joint intervention (n = 55) groups. The conventional group received mitomycin and routine nursing, while the joint intervention group received EPI and mindfulness intervention. Both groups underwent three cycles of chemotherapy. Immune function (CD4+ cells, CD8+ cells, CD4+/CD8+ ratio), tumor marker levels [urinary bladder cancer antigen (UBC), bladder tumor antigen (BTA) and nuclear matrix protein 22 (NMP22)], quality of life questionnaire-core 30 (QLQ-C30), 17-item Hamilton depression scale (HAMD-17), and cancer-related fatigue [cancer fatigue scale (CFS)] were assessed. Adverse reactions and nursing satisfaction were recorded and evaluated.

Results: Post-intervention, CD4+, CD8+, and CD4+/CD8+ levels increased in both groups, with the joint intervention group showing more significant improvement (P < 0.05). Tumor marker levels (NMP22, BTA, and UBC) were lower in the joint intervention group compared to the conventional group (P < 0.05). The joint intervention group also showed a greater reduction in HAMD-17 scores (9.38 ± 3.12 vs 15.45 ± 4.86, P < 0.05), higher QLQ-C30 scores, and lower CFS scores (both P < 0.05). Additionally, the joint intervention group had a lower incidence of adverse reactions and higher nursing satisfaction (P < 0.05).

Conclusion: EPI combined with mindfulness intervention significantly improved clinical outcomes in patients with urinary system tumors and depression and is worthy of clinical application.

背景:泌尿系统肿瘤患者常出现抑郁、烦躁等负性心理症状,严重影响免疫功能,间接影响肿瘤预后。虽然表柔比星(EPI)是欧洲泌尿外科协会推荐的药物,可以改善预后,但长期使用会引起毒副作用,降低治疗依从性,增加心理负担。因此,适当的干预方式是必要的。目的:探讨EPI联合正念干预在泌尿系统肿瘤伴抑郁患者中的临床应用价值。方法:这是一项回顾性研究,包括2021年3月至2023年7月驻马店中心医院收治的110例泌尿系统肿瘤和抑郁症患者。患者分为常规组(n = 55)和联合干预组(n = 55)。常规组给予丝裂霉素和常规护理,联合干预组给予EPI和正念干预。两组患者均接受了三个周期的化疗。评估免疫功能(CD4+细胞、CD8+细胞、CD4+/CD8+比值)、肿瘤标志物水平[膀胱癌抗原(UBC)、膀胱肿瘤抗原(BTA)和核基质蛋白22 (NMP22)]、生活质量问卷-核心30 (QLQ-C30)、17项汉密尔顿抑郁量表(HAMD-17)、癌症相关疲劳量表(CFS)。记录不良反应及护理满意度并进行评价。结果:干预后两组患者CD4+、CD8+及CD4+/CD8+水平均升高,以联合干预组改善更为显著(P < 0.05)。联合干预组肿瘤标志物(NMP22、BTA、UBC)水平低于常规组(P < 0.05)。联合干预组HAMD-17评分降低幅度更大(9.38±3.12 vs 15.45±4.86,P < 0.05), QLQ-C30评分升高,CFS评分降低(P < 0.05)。联合干预组不良反应发生率较低,护理满意度较高(P < 0.05)。结论:EPI联合正念干预可显著改善泌尿系统肿瘤合并抑郁患者的临床疗效,值得临床推广应用。
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引用次数: 0
Comprehensive bibliometric analysis of pharmacotherapy for bipolar disorders: Present trends and future directions. 双相情感障碍药物治疗的综合文献计量学分析:当前趋势和未来方向。
IF 3.9 4区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-19 DOI: 10.5498/wjp.v15.i1.100685
Bo-Fan Chen, Li Liu, Fang-Zhen Lin, Hai-Min Zeng, Hai-Qiang Huang, Chun-Fang Zhang, Cong-Cong Liu, Xiang Chen, Jie Peng, Yun-Fa Wang, Zhi-Lin Wang, Bin Chen, De-Le Liu, Yun Liu, Zheng-Zheng Li, Xin-Xing Zeng

Background: Bipolar disorder (BD) is a severe mental illness characterized by significant mood swings. Effective drug treatment modalities are crucial for managing BD.

Aim: To analyze the current status and future trends of global research on BD drug treatment over the last decade.

Methods: The Web of Science Core Collection database spanning from 2015 to 2024 was utilized to retrieve literature related to BD drug treatment. A total of 2624 articles were extracted. Data visualization and analysis were conducted using CiteSpace, VOSviewer, Pajek, Scimago Graphica, and R-studio bibliometrix to identify research hotspots, key contributors, and future trends.

Results: The United States, China, and the United Kingdom have made the most significant contributions to research on BD drug treatment and formed notable research collaboration networks. The University of Pittsburgh, Massachusetts General Hospital, and the University of Michigan have been identified as the major research institutions in this field. The Journal of Affective Disorders is the most influential journal. A keyword analysis revealed research hotspots related to clinical symptoms, drug efficacy, and genetic mechanisms. A citation analysis identified the management guidelines published by Yatham et al in 2018 as the most cited paper.

Conclusion: This study provides a detailed overview of the field of BD drug treatment, highlighting key contributors, research hotspots, and future directions. The study findings can be employed as a reference for future research and policymaking, which may enable further development and optimization of BD pharmacotherapy.

背景:双相情感障碍(BD)是一种以显著情绪波动为特征的严重精神疾病。有效的药物治疗方式是治疗双相障碍的关键。目的:分析近十年来全球双相障碍药物治疗研究的现状及未来趋势。方法:利用Web of Science Core Collection数据库2015 - 2024年检索双相障碍药物治疗相关文献。共提取2624篇文章。利用CiteSpace、VOSviewer、Pajek、Scimago Graphica和R-studio bibliometrix等工具对数据进行可视化分析,确定研究热点、关键贡献者和未来趋势。结果:美国、中国和英国对双相障碍药物治疗的研究贡献最大,形成了显著的研究合作网络。匹兹堡大学、马萨诸塞州总医院和密歇根大学已被确定为该领域的主要研究机构。《情感障碍杂志》是最有影响力的杂志。关键词分析揭示了临床症状、药物疗效、遗传机制等方面的研究热点。引用分析发现,Yatham等人在2018年发表的管理指南是被引用最多的论文。结论:本研究对双相障碍药物治疗领域进行了详细的概述,突出了关键贡献者、研究热点和未来发展方向。研究结果可为今后的研究和政策制定提供参考,为BD药物治疗的进一步发展和优化提供参考。
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引用次数: 0
Mediating role of health literacy in the relationship between social isolation and psychological distress among pre-frail older adults. 健康素养在体弱多病老年人社会孤立与心理困扰关系中的中介作用。
IF 3.9 4区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-19 DOI: 10.5498/wjp.v15.i1.100953
Juan Fang, Li-Hui Li, Ming-Qian He, Yue Ji, Dong-Yan Lu, Li-Bing Zhang, Jin-Lan Yao

Background: Frailty has become a significant public health issue. The recent increase in the number of frail older adults has led to increased attention being paid to psychological care services in communities. The social isolation of pre-frail older adults can impact their psychological distress.

Aim: To explore the mediating effect of health literacy between social isolation and psychological distress among communitydwelling older adults with pre-frailty.

Methods: This descriptive cross-sectional study was conducted with 254 pre-frail older individuals aged 60 years and over. Social isolation, health literacy, and psychological distress were comprehensively measured using the Lubben Social Network Scale-6, 12-item Short-Form Health Literacy Questionnaire, and the Kessler Psychological Distress Scale-10. Data were evaluated using the SPSS 27.0 package program and the PROCESS macro tool. Descriptive statistical analyses, correlation analyses, and bootstrap mediation tests were used to assess associations between the variables.

Results: The results showed that social isolation had an effect on health literacy among pre-frail older adults (β = 0.240, P < 0.001), social isolation impact on psychological distress pre-frail older adults (β = -0.415, P < 0.001); health literacy was identified effect on psychological distress among pre-frail older persons (β = -0.307, P < 0.001). Health literacy partially mediated the relationship between social isolation and psychological distress among community-dwelling older adults with pre-frailty, with a mediation effect of -0.074, accounting for 17.83% of the total effect.

Conclusion: Health literacy significantly affects the relationship between social isolation and psychological distress among pre-frail older adults. Apart from fostering social connections, improved health literacy measures should be considered.

背景:虚弱已成为一个重要的公共卫生问题。最近体弱多病的老年人人数增加,这使人们更加重视社区的心理护理服务。体弱多病的老年人的社会孤立会影响他们的心理困扰。目的:探讨健康素养在社区老年体弱前期老年人社会孤立与心理困扰之间的中介作用。方法:对254名60岁及以上的体弱前老年人进行描述性横断面研究。采用Lubben社会网络量表-6、12项简短健康素养问卷和Kessler心理困扰量表-10对社会隔离、健康素养和心理困扰进行综合测量。使用SPSS 27.0软件包程序和PROCESS宏工具对数据进行评估。使用描述性统计分析、相关分析和自举中介检验来评估变量之间的关联。结果:社会孤立对体弱前老年人健康素养有影响(β = 0.240, P < 0.001),社会孤立对体弱前老年人心理困扰有影响(β = -0.415, P < 0.001);健康素养对体弱前老年人的心理困扰有影响(β = -0.307, P < 0.001)。健康素养在社区居住老年人社会孤立与心理困扰之间起到部分中介作用,中介效应为-0.074,占总效应的17.83%。结论:健康素养显著影响体弱前老年人社会孤立与心理困扰的关系。除了促进社会联系外,还应考虑改进卫生知识普及措施。
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World Journal of Psychiatry
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