[Model selection for determination of primary stability of dental implants in experimental studies].

Q4 Medicine Stomatologiya Pub Date : 2024-01-01 DOI:10.17116/stomat202410306253

A A Kulakov, A T Begyan

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Abstract

Objective: Systematic review of literature on the pre-clinical studies of dental implantation in different models by finding out data about primary stability.

Materials and methods: PubMed, NCBI, Wiley Online Library, MBPI, Elibrary systems were used for search.

Results: Based on the literature review of the described animal species dogs have the most similar bone structure to humans but their usage is complicated by ethics and law reasons. They are next followed by rabbits with a frequency of use of 35%. Small ruminants', pigs' and mini-pigs' bones are close to human bones and their use is not ethically complicated. The mini-pig model allows assessing bone and soft tissue status of the previously surgical treated area for a sufficient time. Polyurethane blocks have been proposed as an artificial substitute for in vitro simulation in dental implant placement. The advantage of this material is its homogeneous structure.

Conclusion: Small ruminants, pigs and mini-pigs are the most optimal for preclinical studies on dental implantation.

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[实验研究中测定牙种植体初代稳定性的模型选择]。

目的：系统回顾不同模型种植体临床前研究的文献，了解种植体的初代稳定性。材料和方法：PubMed， NCBI, Wiley Online Library， MBPI，图书馆系统进行检索。结果：根据文献综述，犬类的骨骼结构与人类最为相似，但由于伦理和法律原因，犬类的使用较为复杂。其次是兔子，使用频率为35%。小反刍动物、猪和迷你猪的骨头与人类的骨头很接近，它们的使用在伦理上并不复杂。迷你猪模型允许在足够的时间内评估先前手术治疗区域的骨和软组织状态。聚氨酯块已被提出作为人工替代体外模拟牙种植体放置。这种材料的优点是结构均匀。结论：小反刍动物、猪和小型猪是牙种植临床前研究的最佳动物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Stomatologiya Medicine-Medicine (all)

CiteScore

0.40

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0.00%

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