[Etiology and pathophysiology of Frey syndrome].

Abstract

Frey syndrome is a late complication after parotidectomy and represents an aberrant regeneration of the auricular nerve after its damage. The degree of manifestation can vary from minor hyperemia to the inability to eat in public places. As it turned out, the etiology of this syndrome is much broader than we might have assumed, as evidenced by the data of domestic and foreign literature. The role of neurotrophic factors in the context of the pathophysiology of Frey syndrome has been the latest clue since its interpretation by Lucia Frey in 1923. The review highlights the various etiological and pathophysiological components of Frey syndrome that help the clinician in his medical practice.