A case of kerion celsi caused by Trichophyton tonsurans with dermatophytid reaction mimicking a drug eruption and endothrix infection confirmed in pathological tissue

IF 1.3 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Medical Mycology Case Reports Pub Date : 2024-12-25 DOI:10.1016/j.mmcr.2024.100691
Makoto Ishiai, Hiroshi Tanabe
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Abstract

We report a case of kerion celsi caused by Trichophyton tonsurans in a teenage male judo athlete, presenting with a lesion in the occipital region. Following the initiation of systemic antifungal therapy, the patient developed a dermatophytid reaction, necessitating differentiation from a drug eruption. Direct microscopy of the affected area confirmed the presence of fungal elements, and histopathological examination revealed endothrix invasion, supporting the continuation of treatment. A drug-induced lymphocyte stimulation test for terbinafine, conducted post-treatment, was negative. This case highlights the importance of distinguishing dermatophytid reactions from drug eruptions to ensure uninterrupted antifungal therapy.

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病理组织证实1例由疣状毛癣引起的角质细胞,伴有类似药疹的皮肤癣反应和粘膜感染。
我们报告一个病例的kerion celsi由毛癣引起的一个十几岁的男性柔道运动员,呈现病变在枕区。在开始全身抗真菌治疗后,患者出现皮肤癣反应,需要与药疹鉴别。直接显微镜检查患处证实真菌元素的存在,组织病理学检查显示粘膜浸润,支持继续治疗。治疗后对特比萘芬进行药物诱导淋巴细胞刺激试验,结果为阴性。本病例强调区分皮肤癣反应与药物疹的重要性,以确保不间断的抗真菌治疗。
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来源期刊
Medical Mycology Case Reports
Medical Mycology Case Reports MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
4.00
自引率
0.00%
发文量
48
审稿时长
47 days
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