Linda B Neubrand, Xavier Attendu, Ton G van Leeuwen
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Abstract
In this study, we aim to validate the analytical Cramer-Rao lower bound (CRLB) equation for determining attenuation coefficients using a 1310 nm Optical Coherence Tomography (OCT) system. Our experimental results successfully confirm the validity of the equation, achieving unprecedented precision with a standard deviation below 0.01 mm-1 for intralipid samples. Furthermore, we introduce a systematic framework for attaining high precision in OCT attenuation measurements.
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