Skeletal Maturity Might Not Be a Factor in Optimizing Outcomes in Total Hip Arthroplasty.

IF 1 Q3 MEDICINE, GENERAL & INTERNAL Cureus Pub Date : 2025-01-16 eCollection Date: 2025-01-01 DOI:10.7759/cureus.77526
Correggio L Peagler, Philip Parel, Kennedy Musgrave, Sarah Dance, Roxana Martinez, Savyasachi C Thakkar, Sean A Tabaie
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Abstract

Introduction Total hip arthroplasty (THA) is rarely indicated in the skeletally immature population. In these instances, there is concern for implant survival compared to the traditional older population. There has been a steady rise in the use of THA in the pediatric population due to improvements in surgical techniques. While the outcomes in THA for skeletally immature patients have been described in the literature, there are no population studies looking at this procedure in a skeletally immature individual. Therefore, the purpose of this study was to compare 10-year implant survivability following primary THA in skeletally mature versus skeletally immature patients. Methods Patients who underwent primary THA were identified using a large national database (PearlDiver). THA patients were then divided into presumed skeletally immature male patients (0-16 years), presumed skeletally mature male patients (17-21 years), presumed skeletally immature females (0-14 years), and presumed skeletally mature females (15-21 years). Multivariable analysis was conducted using Cox proportional hazards modeling to determine differences in the risk of revision for periprosthetic joint infection (PJI), mechanical loosening, dislocation/instability, and periprosthetic fracture (PPF). Results In total, 352 male patients (244 skeletally mature and 108 skeletally immature) and 409 female patients (350 skeletally mature and 59 skeletally immature) were identified. Compared to skeletally immature females, skeletally mature females had no higher risk of 10-year revision for all-cause, PJI, mechanical loosening, dislocation/instability, or PPF (P > 0.05 for all). Compared to skeletally immature males, skeletally mature males had no higher risk of 10-year revision for all-cause, PJI, mechanical loosening, dislocation/instability, or PPF (P > 0.05 for all). Conclusion Although THA occurred more commonly in patients above the presumed age of skeletal maturity, the lack of significantly different surgical outcomes suggests that younger age and presumed skeletal immaturity may not put patients at any further risk of implant failure. While further research is needed to understand the impact of age and skeletal maturity on outcomes of THA, these results indicate that the initial age of a THA may not be a factor in optimizing outcomes, and suggests that orthopedic surgeons need not delay surgery based on age or skeletal maturity alone.

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骨骼成熟度可能不是优化全髋关节置换术结果的一个因素。
全髋关节置换术(THA)很少适用于骨骼发育不成熟的人群。在这些情况下,与传统的老年人群相比,人们担心种植体的存活率。由于手术技术的改进,在儿科人群中使用全髋关节置换术的人数稳步上升。虽然文献中已经描述了骨未成熟患者THA的结果,但没有针对骨未成熟个体的人群研究。因此,本研究的目的是比较骨骼成熟和骨骼不成熟患者原发性THA后10年的种植体存活率。方法使用大型国家数据库(PearlDiver)对接受原发性THA的患者进行识别。然后将THA患者分为假定骨骼不成熟男性患者(0-16岁)、假定骨骼成熟男性患者(17-21岁)、假定骨骼不成熟女性患者(0-14岁)和假定骨骼成熟女性患者(15-21岁)。采用Cox比例风险模型进行多变量分析,以确定假体周围关节感染(PJI)、机械松动、脱位/不稳定和假体周围骨折(PPF)翻修风险的差异。结果男性352例(骨骼成熟244例,骨骼未成熟108例),女性409例(骨骼成熟350例,骨骼未成熟59例)。与骨骼未成熟的女性相比,骨骼成熟的女性因全因、PJI、机械松动、脱位/不稳定或PPF进行10年翻修的风险没有更高(P < 0.05)。与骨骼不成熟的男性相比,骨骼成熟的男性在全因、PJI、机械松动、脱位/不稳定或PPF方面的10年翻修风险没有更高(P < 0.05)。结论:尽管THA在假定骨骼成熟年龄以上的患者中更常见,但手术结果没有明显差异,这表明年龄较小和假定骨骼不成熟可能不会使患者面临任何进一步的植入失败风险。虽然需要进一步的研究来了解年龄和骨骼成熟度对THA结果的影响,但这些结果表明THA的初始年龄可能不是优化结果的一个因素,并建议骨科医生不需要仅根据年龄或骨骼成熟度延迟手术。
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