{"title":"Phase-gradient force-based optical array sorter","authors":"Yixuan Wu, Yu Liu, Shaohua Tao","doi":"10.1063/5.0238242","DOIUrl":null,"url":null,"abstract":"Microparticle sorting is crucial for applications in biomedicine, environmental monitoring, and biochip technology. However, traditional optical sorting methods often rely on external equipment, such as microfluidic devices. In this Letter, we proposed a phase-gradient force-based optical array sorting (POAS) scheme, which achieves the accurate transporting and sorting of the particles by regulating the phase-gradient force based on the physical characteristics of the particles. The method combines the function of particle transporting and sorting, eliminating the need for external auxiliary equipment. Based on the POAS scheme, we used the complex amplitude beam shaping algorithms to design a 1 × 2 array sorting beam with the controllable phase-gradient forces. The array sorting beam was used to experimentally sort two kinds of particles with different sizes, and the particles are first transported and then precisely sorted at the designated sorting nodes. All the parameters of the sorting beam were adjustable, which greatly enhances the flexibility and scalability of the optical sorting technology. This study provides an alternative scheme for the high-throughput particle sorting, which can be easily integrated into the optical sorting chips for applications in medical detection and drug delivery.","PeriodicalId":8094,"journal":{"name":"Applied Physics Letters","volume":"22 1","pages":""},"PeriodicalIF":3.5000,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Physics Letters","FirstCategoryId":"101","ListUrlMain":"https://doi.org/10.1063/5.0238242","RegionNum":2,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHYSICS, APPLIED","Score":null,"Total":0}
引用次数: 0
Abstract
Microparticle sorting is crucial for applications in biomedicine, environmental monitoring, and biochip technology. However, traditional optical sorting methods often rely on external equipment, such as microfluidic devices. In this Letter, we proposed a phase-gradient force-based optical array sorting (POAS) scheme, which achieves the accurate transporting and sorting of the particles by regulating the phase-gradient force based on the physical characteristics of the particles. The method combines the function of particle transporting and sorting, eliminating the need for external auxiliary equipment. Based on the POAS scheme, we used the complex amplitude beam shaping algorithms to design a 1 × 2 array sorting beam with the controllable phase-gradient forces. The array sorting beam was used to experimentally sort two kinds of particles with different sizes, and the particles are first transported and then precisely sorted at the designated sorting nodes. All the parameters of the sorting beam were adjustable, which greatly enhances the flexibility and scalability of the optical sorting technology. This study provides an alternative scheme for the high-throughput particle sorting, which can be easily integrated into the optical sorting chips for applications in medical detection and drug delivery.
期刊介绍:
Applied Physics Letters (APL) features concise, up-to-date reports on significant new findings in applied physics. Emphasizing rapid dissemination of key data and new physical insights, APL offers prompt publication of new experimental and theoretical papers reporting applications of physics phenomena to all branches of science, engineering, and modern technology.
In addition to regular articles, the journal also publishes invited Fast Track, Perspectives, and in-depth Editorials which report on cutting-edge areas in applied physics.
APL Perspectives are forward-looking invited letters which highlight recent developments or discoveries. Emphasis is placed on very recent developments, potentially disruptive technologies, open questions and possible solutions. They also include a mini-roadmap detailing where the community should direct efforts in order for the phenomena to be viable for application and the challenges associated with meeting that performance threshold. Perspectives are characterized by personal viewpoints and opinions of recognized experts in the field.
Fast Track articles are invited original research articles that report results that are particularly novel and important or provide a significant advancement in an emerging field. Because of the urgency and scientific importance of the work, the peer review process is accelerated. If, during the review process, it becomes apparent that the paper does not meet the Fast Track criterion, it is returned to a normal track.