{"title":"Spectral control of photoenzyme through allosteric chromophore tuning","authors":"Menghan Xu, Yuki Yamanashi, Motomu Kanai","doi":"10.1016/j.chempr.2025.102430","DOIUrl":null,"url":null,"abstract":"Artificial photoenzymes offering non-natural reactivities present a promising synthetic strategy, yet the use of red light remains challenging. In this issue of <em>Chem</em>, Gregory D. Scholes, Sijia S. Dong, Todd K. Hyster, and coworkers reported a groundbreaking approach to engineering a photoenzyme to use red light by tuning the protein microenvironment, opening a new window for chem-bio catalysis.","PeriodicalId":268,"journal":{"name":"Chem","volume":"1 1","pages":""},"PeriodicalIF":19.1000,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chem","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1016/j.chempr.2025.102430","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Artificial photoenzymes offering non-natural reactivities present a promising synthetic strategy, yet the use of red light remains challenging. In this issue of Chem, Gregory D. Scholes, Sijia S. Dong, Todd K. Hyster, and coworkers reported a groundbreaking approach to engineering a photoenzyme to use red light by tuning the protein microenvironment, opening a new window for chem-bio catalysis.
提供非自然反应的人工光酶是一种很有前途的合成策略,但红光的使用仍然具有挑战性。在这一期的《化学》杂志上,Gregory D. Scholes, Sijia S. Dong, Todd K. Hyster及其同事报道了一种开创性的方法,通过调节蛋白质微环境来设计一种光酶,使其使用红光,为化学-生物催化打开了一扇新的窗口。
期刊介绍:
Chem, affiliated with Cell as its sister journal, serves as a platform for groundbreaking research and illustrates how fundamental inquiries in chemistry and its related fields can contribute to addressing future global challenges. It was established in 2016, and is currently edited by Robert Eagling.