Microsurgical Repair of Large Nasal Septal Defects.

IF 1.6 4区 医学 Q3 SURGERY Annals of Plastic Surgery Pub Date : 2025-03-01 Epub Date: 2025-01-23 DOI:10.1097/SAP.0000000000004218
Robert L Walton, Nicole Gherlone, Jenny Bai
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Abstract

Background: Nasal septal defects cause considerable morbidity and represent a challenging reconstructive problem. Traditional repair techniques have employed local intranasal tissues and allograft adjuncts. For large septal defects (>4-5 cm 2 ), less than half are successfully resolved.

Methods: We conducted a retrospective review of patients presenting with large (>4 cm 2 ) nasal septal defects treated by microsurgical septal reconstruction using various engineered or prelaminated flaps.

Results: Nine consecutive patients were included in this study. Defect size averaged 7.89 cm 2 (range 4.5-13.5 cm 2 ). There were 4 males/5 females. Average age was 49.3 years (range 34.4-76.2 years). Follow-up averaged 10.1 years (range 1.3-25.8 years). Etiology of the septal defects included cocaine (4), neoplasm (2), surgery (1), autoimmune disease (1), and infection (1). Flaps utilized: prelaminated radial forearm flap (3), prelaminated (skin only) radial forearm flap (3), folded radial forearm flap (1), first dorsal metacarpal artery flap (1), and engineered superficial inferior epigastric artery flap (1). There were no flap losses. Recurrent septal perforation occurred in 3 patients. The first patient developed a small 0.5-cm diameter anterior perforation that was the result of a local infection. This was successfully closed using local mucosal flaps. Recurrent septal perforations (each less than 1-cm diameter) were identified in 2 additional patients. In each of these patients, the perforation was located at the posterior, inferior aspect of the septal repair site. An attempt to repair one of these defects was unsuccessful but the defect has remained stable and asymptomatic. Similarly, the other recurrent perforation has also remained asymptomatic and is being managed conservatively. The remaining healed septal defects have remained stable over time without airway obstruction.

Conclusions: This experience underscores the significant clinical challenges confronting repair of large nasal septal defects. Our results demonstrate the safety and utility of microsurgical reconstruction in this setting. Technical precision in flap inset has emerged as a key requisite for a successful outcome. The application of engineered/prelaminated flaps for these defects represents a novel approach to management.

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大鼻中隔缺损的显微外科修复:大鼻中隔缺损的显微外科修复。
背景:鼻中隔缺损引起相当高的发病率,是一个具有挑战性的重建问题。传统的修复技术采用局部鼻内组织和同种异体移植辅助材料。对于较大的间隔缺损(4-5 cm2),成功解决的不到一半。方法:我们对采用各种工程皮瓣或预层压皮瓣进行显微外科鼻中隔重建术治疗鼻中隔大(bbbb4 cm2)缺损的患者进行回顾性分析。结果:本研究连续纳入9例患者。缺陷尺寸平均为7.89 cm2(范围4.5-13.5 cm2)。男性4人,女性5人。平均年龄49.3岁(34.4 ~ 76.2岁)。随访平均10.1年(1.3-25.8年)。鼻中隔缺损的病因包括可卡因(4例)、肿瘤(2例)、手术(1例)、自身免疫性疾病(1例)和感染(1例)。皮瓣使用:前臂桡侧预层压皮瓣(3例)、前臂桡侧预层压皮瓣(3例)、前臂桡侧折叠皮瓣(1例)、第一掌背动脉皮瓣(1例)和工程腹壁下浅动脉皮瓣(1例)。没有皮瓣损失。3例复发性中隔穿孔。第一位患者出现了一个直径0.5 cm的小前穿孔,这是局部感染的结果。使用局部粘膜瓣成功闭合。另外2例患者发现复发性间隔穿孔(每个直径小于1厘米)。在这些患者中,穿孔位于间隔修复部位的后下方。试图修复这些缺陷之一是不成功的,但缺陷一直保持稳定和无症状。同样,其他复发穿孔也没有症状,正在进行保守治疗。其余愈合的间隔缺损随着时间的推移保持稳定,没有气道阻塞。结论:这一经验强调了修复大面积鼻中隔缺损所面临的重大临床挑战。我们的结果证明了显微外科重建在这种情况下的安全性和实用性。皮瓣插入的技术精度已成为成功的关键条件。工程/预层压皮瓣对这些缺陷的应用代表了一种新的管理方法。
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来源期刊
CiteScore
2.70
自引率
13.30%
发文量
584
审稿时长
6 months
期刊介绍: The only independent journal devoted to general plastic and reconstructive surgery, Annals of Plastic Surgery serves as a forum for current scientific and clinical advances in the field and a sounding board for ideas and perspectives on its future. The journal publishes peer-reviewed original articles, brief communications, case reports, and notes in all areas of interest to the practicing plastic surgeon. There are also historical and current reviews, descriptions of surgical technique, and lively editorials and letters to the editor.
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