Ocular invasion in sinonasal malignant melanoma: A case report and review of literature

IF 0.7 Q4 SURGERY International Journal of Surgery Case Reports Pub Date : 2025-02-01 Epub Date: 2025-01-20 DOI:10.1016/j.ijscr.2025.110904
Bijan Khademi , Sajjad Soltani , Alireza Yousefi , Pouya Heidari , Zhale Mardani , Shayan Yousufzai
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Abstract

Background

Sinonasal mucosal melanoma (SNMM) is a rare and aggressive malignancy associated a poor prognosis, prognosis. It is by delayed presentation and nonspecific symptoms. The incidence of SNMM is low, with and there are challenges in achieving local control and managing distant metastases.
Case Presentation.
We report present case of an 86-year-old female patient with a history of systemic hypertension who presented exhibited symptoms, including blurred vision, rhinorrhea, and facial pain, following initial treatment for SNMM. sinonasal mucosal melanoma (SNMM). studies revealed a heterogeneous lesion in the right nasal cavity and ethmoidal air cells, exhibiting characterized by destruction and invasion into the orbit. The patient underwent functional endoscopic sinus surgery (FESS) for resection, with and analysis confirming confirmed the diagnosis of melanoma.

Discussion

This case underscores the aggressive nature of SNMM and emphasizes importance of early diagnosis and intervention. Despite Although treatment with surgery and radiotherapy leading resulted in resolution for two years, the recurrence of symptoms highlights the challenges in associated with long-term control. The Effective of SNMM requires necessitates multidisciplinary approach, approach that includes resection and the of adjuvant therapies.

Conclusion

SNMM poses presents treatment challenges due to its aggressive behavior nature complex anatomical location. A comprehensive approach involving that includes radiotherapy, and potential systemic therapies is essential for improving enhancing outcomes. Further research is needed necessary explore investigate treatment strategies for this rare malignancy.
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鼻窦恶性黑色素瘤侵犯眼部:1例报告及文献复习。
背景:鼻黏膜黑色素瘤(SNMM)是一种罕见的侵袭性恶性肿瘤,预后较差。它是由延迟表现和非特异性症状引起的。SNMM的发病率很低,并且在实现局部控制和管理远处转移方面存在挑战。病例介绍:我们报告一例86岁的女性患者,有全身性高血压病史,在接受SNMM初始治疗后,表现出视力模糊、鼻漏和面部疼痛等症状。鼻黏膜黑色素瘤(SNMM)。研究显示右鼻腔和筛气细胞有异质病变,表现为破坏和侵入眼眶。患者接受功能性内窥镜鼻窦手术(FESS)切除,与分析证实了黑色素瘤的诊断。讨论:本病例强调了SNMM的侵袭性,强调了早期诊断和干预的重要性。尽管以手术和放疗为主的治疗可以缓解两年,但症状的复发突出了与长期控制相关的挑战。SNMM的有效治疗需要多学科的方法,包括切除和辅助治疗。结论:SNMM具有攻击行为和复杂的解剖位置,给治疗带来了挑战。综合治疗方法包括放射治疗和潜在的全身治疗,对于改善和增强预后至关重要。这一罕见恶性肿瘤的治疗策略有待进一步研究。
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来源期刊
CiteScore
1.10
自引率
0.00%
发文量
1116
审稿时长
46 days
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