Obsessive-compulsive symptoms and personal recovery in patients with schizophrenia spectrum disorders: A cross-sectional study

IF 3.5 2区 医学 Q1 PSYCHIATRY Schizophrenia Research Pub Date : 2025-02-01 Epub Date: 2025-01-21 DOI:10.1016/j.schres.2025.01.008
A. Jelsma , F. Schirmbeck , M. van der Pluijm , C. Simons , A. Vellinga , M. de Koning , L. de Haan
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Abstract

Background

Obsessive-compulsive symptoms (OCS) frequently co-occur in patients with Schizophrenia Spectrum Disorders (SSD). Patients with SSD and OCS experience increased clinical and social challenges, including diminished quality of life and subjective well-being. However, it is unknown whether co-morbid OCS are associated with personal recovery.

Aim

To investigate whether the presence and severity of OCS in patients with SSD is associated with lower self-reported personal recovery.

Methods

A cross-sectional design was employed, examining 527 patients with SSD. Group comparisons between patients with and without OCS for self-reported personal recovery (assessed with the Recovery Assessment Scale (RAS-24)) were conducted using analysis of covariance, adjusting for positive, negative and general symptoms. Multiple regression analyses were performed in 133 patients with co-occurring OCS to assess the additional explained variance in personal recovery by OCS severity after adjusting for the same covariates in the first block of the model.

Results

Group comparisons demonstrated that the presence of co-morbid OCS was associated with lower scores in personal recovery. Multiple hierarchical regression analyses showed that OCS severity was significantly associated with personal recovery by explaining an additional 3.0 % of variance in personal recovery.

Conclusion

Our findings suggest that co-occurring OCS in patients with SSD are relevant for personal recovery and that treatment should also address OCS.
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精神分裂症谱系障碍患者的强迫症状和个人康复:一项横断面研究
背景:强迫症状(OCS)经常在精神分裂症谱系障碍(SSD)患者中同时出现。患有SSD和OCS的患者面临更多的临床和社会挑战,包括生活质量和主观幸福感下降。然而,目前尚不清楚共病性OCS是否与个人康复有关。目的:探讨SSD患者OCS的存在和严重程度是否与较低的自我报告个人恢复有关。方法:采用横断面设计,对527例SSD患者进行分析。采用协方差分析,调整阳性、阴性和一般症状,对有OCS和无OCS患者自我报告的个人恢复(用恢复评估量表(RAS-24)评估)进行组间比较。对133例同时发生OCS的患者进行多元回归分析,以评估在模型第一部分调整相同协变量后,OCS严重程度对个人恢复的额外解释方差。结果:组间比较表明,共病OCS的存在与个人康复得分较低有关。多层次回归分析表明,OCS严重程度与个人恢复显著相关,解释了个人恢复的额外3.0%方差。结论:我们的研究结果表明,SSD患者同时发生的OCS与个人康复有关,治疗也应针对OCS。
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来源期刊
Schizophrenia Research
Schizophrenia Research 医学-精神病学
CiteScore
7.50
自引率
8.90%
发文量
429
审稿时长
10.2 weeks
期刊介绍: As official journal of the Schizophrenia International Research Society (SIRS) Schizophrenia Research is THE journal of choice for international researchers and clinicians to share their work with the global schizophrenia research community. More than 6000 institutes have online or print (or both) access to this journal - the largest specialist journal in the field, with the largest readership! Schizophrenia Research''s time to first decision is as fast as 6 weeks and its publishing speed is as fast as 4 weeks until online publication (corrected proof/Article in Press) after acceptance and 14 weeks from acceptance until publication in a printed issue. The journal publishes novel papers that really contribute to understanding the biology and treatment of schizophrenic disorders; Schizophrenia Research brings together biological, clinical and psychological research in order to stimulate the synthesis of findings from all disciplines involved in improving patient outcomes in schizophrenia.
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