{"title":"Artificial intelligence propels lung cancer screening: innovations and the challenges of explainability and reproducibility","authors":"Mario Mascalchi, Chiara Marzi, Stefano Diciotti","doi":"10.1038/s41392-024-02111-9","DOIUrl":null,"url":null,"abstract":"<p>In a recent study published in <i>Nature Medicine</i>, Wang, Shao, and colleagues successfully addressed two critical issues of lung cancer (LC) screening with low-dose computed tomography (LDCT) whose widespread implementation, despite its capacity to decrease LC mortality, remains challenging: (1) the difficulty in accurately distinguishing malignant nodules from the far more common benign nodules detected on LDCT, and (2) the insufficient coverage of LC screening in resource-limited areas.<sup>1</sup></p>","PeriodicalId":21766,"journal":{"name":"Signal Transduction and Targeted Therapy","volume":"108 1","pages":""},"PeriodicalIF":40.8000,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Signal Transduction and Targeted Therapy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41392-024-02111-9","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
In a recent study published in Nature Medicine, Wang, Shao, and colleagues successfully addressed two critical issues of lung cancer (LC) screening with low-dose computed tomography (LDCT) whose widespread implementation, despite its capacity to decrease LC mortality, remains challenging: (1) the difficulty in accurately distinguishing malignant nodules from the far more common benign nodules detected on LDCT, and (2) the insufficient coverage of LC screening in resource-limited areas.1
期刊介绍：
Signal Transduction and Targeted Therapy is an open access journal that focuses on timely publication of cutting-edge discoveries and advancements in basic science and clinical research related to signal transduction and targeted therapy.
Scope: The journal covers research on major human diseases, including, but not limited to:
Cancer,Cardiovascular diseases,Autoimmune diseases,Nervous system diseases.
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