[Meta-analysis of the efficacy of plate fixation and external fixator fixation in the treatment of AO-C type distal radius fractures].

Guang-Yao Li, Yong-Zhong Cheng, Huan Liu, Jun-Jie Jiang, Yong-Yao Li, Yang Chen, Yu-Xiang Yao
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引用次数: 0

Abstract

Objective: Meta-analysis of the clinical efficacy of plate and external fixator fixation in the treatment of AO-C type distal radius fractures.

Methods: PubMed, Embase, Cochrane Medical Library, Web of Science, CNKI, Wanfang, VIP and SinoMed databases were searched for all literature on randomized controlled clinical trials of AO-C distal radius fractures. The search time limits were from each database. The database will be established until June 30, 2023. The included studies were extracted according to the Cochrane Handbook (Version 6.3, 2022) for information extraction and literature quality evaluation. RevMan 5.4 was used to evaluate the risk of Publication bias, test heterogeneity and Perform Meta-analysis. The outcome indicators were:imaging anatomy indicators (volar inclination angle, ulnar deviation angle, radial height), wrist joint mobility (flexion, extension, rotation, ulnar deviation), complication rate, and comparison of surgical treatments (operative blood loss, operation time, hospitalization time, fracture healing time) and wrist joint function scores and related scales.

Results: (1) A total of 28 studies were included, with a total of 2 192 patients, including 1 096 cases in the plate internal fixation group and 1 096 cases in the external fixation group.(2) Meta analysis results showed:the surgical treatment situation of the external fixation group:surgical blood loss MD=-37.93, 95%CI(-48.54, -27.31), P<0.000 01;operation time MD=-31.58, 95%CI(-48.96, -14.20), P<0.000 4;hospitalization time MD=-4.58, 95%CI(-5.44, -3.71), P<0.000 01;the fracture healing time MD=-0.88, 95%CI(-1.35, -0.41), P<0.000 2, which were significantly better than that of the plate internal fixation group(P<0.05).(3) The two groups:palmar inclination angle MD=-0.17, 95%CI(-0.95, 0.61), P=0.68;ulnar declination MD=0.22, 95%CI(-0.73, 1.17), P=0.65, radial height MD=-0.24, 95%CI(-1.15, 0.67), P=0.60;flexion and extension MD=-5.63, 95%CI(-11.85, 0.58), P=0.08;rotation MD=-5.80, 95%CI(-12.77, 1.17), P=0.10, radioulnar deviation MD=-2.86, 95%CI(-10.87, 5.15), P=0.48;complication rate RR=0.96, 95%CI(0.63, 1.46), P=0.83;Gartland-Werley clinical wrist score MD=0.13, 95%CI(-0.80, 1.06), P=0.78;excellent and good rate of Gartland-Werley wrist clinical score RR=0.93, 95%CI(0.87, 1.01), P=0.08;excellent and good rate of Cooney wrist score RR=0.99, 95%CI(0.62, 1.59), P=0.98;wrist DASH score MD=-4.67, 95%CI(-14.96, 5.62), P=0.37;the differences were not significant (P>0.05).

Conclusion: Compared with internal fixation with plate, external fixation can significantly reduce the amount of surgical bleeding, shorten the operation time, hospitalization time and fracture healing time, and its imaging anatomical indicators, wrist mobility, and complications can be significantly reduced in treating AO-C distal radius fractures. Rates and wrist function scores were equivalent.

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[钢板内固定与外固定架内固定治疗AO-C型桡骨远端骨折疗效meta分析]。
目的:对钢板与外固定架固定治疗AO-C型桡骨远端骨折的临床疗效进行meta分析。方法:检索PubMed、Embase、Cochrane医学图书馆、Web of Science、中国知网(CNKI)、万方、VIP、中国医学信息网等数据库,检索AO-C型桡骨远端骨折随机对照临床试验相关文献。搜索时间限制来自每个数据库。该数据库将建立到2023年6月30日。纳入的研究根据Cochrane Handbook (Version 6.3, 2022)进行信息提取和文献质量评价。采用RevMan 5.4评估发表偏倚风险,检验异质性并进行meta分析。结局指标为:影像学解剖指标(掌侧倾角、尺侧偏角、桡侧高度)、腕关节活动度(屈伸、旋转、尺侧偏)、并发症发生率、手术治疗比较(手术出血量、手术时间、住院时间、骨折愈合时间)、腕关节功能评分及相关量表。结果:(1)共纳入28项研究,共2 192例患者,其中钢板内固定组1 096例,外固定组1 096例。(2)Meta分析结果显示:外固定组手术治疗情况:手术失血量MD=-37.93, 95%CI(-48.54, -27.31), PMD=-31.58, 95%CI(-48.96, -14.20), PMD=-4.58, 95%CI(-5.44, -3.71), PMD=-0.88, 95%CI(-1.35, -0.41), PPMD=-0.17, 95%CI(-0.95, 0.61), P=0.68;旋转MD=-5.80, 95%CI(-12.77, 1.17), P=0.10,尺桡偏度MD=-2.86, 95%CI(-10.87, 5.15), P=0.48,并发症发生率RR=0.96, 95%CI(0.63, 1.46), P=0.83, Gartland-Werley腕关节临床评分MD=0.13, 95%CI(-0.80, 1.06), P=0.78, Gartland-Werley腕关节临床评分优优率RR=0.93, 95%CI(0.87, 1.01),Cooney腕部评分优良率RR=0.99, 95%CI(0.62, 1.59), P=0.98;腕部DASH评分MD=-4.67, 95%CI(-14.96, 5.62), P=0.37,差异均无统计学意义(P < 0.05)。结论:与钢板内固定相比,外固定可显著减少手术出血量,缩短手术时间、住院时间和骨折愈合时间,且其影像学解剖指标、腕关节活动度及并发症在治疗AO-C型桡骨远端骨折中均可显著减少。速率和腕功能评分相等。
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