Tim Lippold , Julia Kosolapova , Niko T. Flosbach , Robert Herzhoff , Axel G. Griesbeck , Mathias Wickleder
{"title":"Thiolate-CLPG (chemiluminescent protecting groups) based on coumaranone thiolcarbamates†","authors":"Tim Lippold , Julia Kosolapova , Niko T. Flosbach , Robert Herzhoff , Axel G. Griesbeck , Mathias Wickleder","doi":"10.1039/d4cc06150k","DOIUrl":null,"url":null,"abstract":"<div><div>The base-induced oxidative release of aromatic and aliphatic thiols from novel coumaranone-thiolurethanes 3a–3e is accompanied by long-lasting blue or green chemiluminescence. Thus, these compounds serve as base/oxidation-labile protecting groups that decompose with strong visible luminescence and subsequent quantitative release of the protected thiolate as leaving group.</div></div>","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":"61 25","pages":"Pages 4792-4795"},"PeriodicalIF":4.2000,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/cc/d4cc06150k?page=search","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemical Communications","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S1359734525004057","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
The base-induced oxidative release of aromatic and aliphatic thiols from novel coumaranone-thiolurethanes 3a–3e is accompanied by long-lasting blue or green chemiluminescence. Thus, these compounds serve as base/oxidation-labile protecting groups that decompose with strong visible luminescence and subsequent quantitative release of the protected thiolate as leaving group.
期刊介绍:
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