Role of Antidepressants in Acute Coronary Syndrome: An Evidence-Based Case Report.

IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Acta medica Indonesiana Pub Date : 2024-10-01

Hamzah Shatri, Nabella Qisthina Laksita Dewi, Vinandia Irvianita, Edward Faisal, Rudi Putranto

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引用次数: 0

Abstract

Background: Acute coronary syndrome (ACS) and depression are related to each other. Detection and proper treatment of these conditions can improve functional ability and quality of life. However, there is still controversy in this population regarding the use, safety, and efficacy of antidepressant pharmacotherapy. This evidence-based case report (EBCR) aims to determine the role of antidepressants in acute coronary syndrome patients.

Methods: Literature searching was performed using online databases such as EBSCO, Embase, PubMed, ClinicalKey, and ScienceDirect according to clinical questions. The studies were selected based on the suitability of the inclusion and exclusion criteria followed by critical appraisal.

Results: In patients with ACS, antidepressants do not affect mortality but may reduce rehospitalization. In patients with ACS and depression who received antidepressants, there is a reduced risk of myocardial infarction (MI) recurrence. In post-ACS patients, the use of antidepressants is associated with a reduced risk of recurrent MI.

Conclusion: In ACS patients, antidepressants do not affect mortality, but can reduce the incidence of myocardial reinfarction.

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抗抑郁药在急性冠脉综合征中的作用：一项基于证据的病例报告。

背景：急性冠脉综合征（ACS）与抑郁症之间存在一定的相关性。这些疾病的发现和适当的治疗可以改善功能能力和生活质量。然而，在这一人群中，关于抗抑郁药物治疗的使用、安全性和有效性仍然存在争议。本循证病例报告（EBCR）旨在确定抗抑郁药在急性冠状动脉综合征患者中的作用。方法：根据临床问题，利用EBSCO、Embase、PubMed、ClinicalKey、ScienceDirect等在线数据库进行文献检索。根据纳入和排除标准的适宜性选择研究，然后进行批判性评价。结果：在ACS患者中，抗抑郁药物不影响死亡率，但可能减少再住院。在ACS和抑郁症患者谁接受抗抑郁药，有心肌梗死（MI）复发的风险降低。结论：在ACS患者中，抗抑郁药物的使用不影响死亡率，但可以降低心肌再梗死的发生率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta medica Indonesiana MEDICINE, GENERAL & INTERNAL-

CiteScore

2.30

自引率

0.00%

发文量

审稿时长

12 weeks

期刊介绍： Acta Medica Indonesiana – The Indonesian Journal of Internal Medicine is an open accessed online journal and comprehensive peer-reviewed medical journal published by the Indonesian Society of Internal Medicine since 1968. Our main mission is to encourage the novel and important science in the clinical area in internal medicine. We welcome authors for original articles (research), review articles, interesting case reports, special articles, clinical practices, and medical illustrations that focus on the clinical area of internal medicine. Subjects suitable for publication include, but are not limited to the following fields of: -Allergy and immunology -Emergency medicine -Cancer and stem cells -Cardiovascular -Endocrinology and Metabolism -Gastroenterology -Gerontology -Hematology -Hepatology -Tropical and Infectious Disease -Virology -Internal medicine -Psychosomatic -Pulmonology -Rheumatology -Renal and Hypertension -Thyroid