{"title":"Role of Antidepressants in Acute Coronary Syndrome: An Evidence-Based Case Report.","authors":"Hamzah Shatri, Nabella Qisthina Laksita Dewi, Vinandia Irvianita, Edward Faisal, Rudi Putranto","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Acute coronary syndrome (ACS) and depression are related to each other. Detection and proper treatment of these conditions can improve functional ability and quality of life. However, there is still controversy in this population regarding the use, safety, and efficacy of antidepressant pharmacotherapy. This evidence-based case report (EBCR) aims to determine the role of antidepressants in acute coronary syndrome patients.</p><p><strong>Methods: </strong>Literature searching was performed using online databases such as EBSCO, Embase, PubMed, ClinicalKey, and ScienceDirect according to clinical questions. The studies were selected based on the suitability of the inclusion and exclusion criteria followed by critical appraisal.</p><p><strong>Results: </strong>In patients with ACS, antidepressants do not affect mortality but may reduce rehospitalization. In patients with ACS and depression who received antidepressants, there is a reduced risk of myocardial infarction (MI) recurrence. In post-ACS patients, the use of antidepressants is associated with a reduced risk of recurrent MI.</p><p><strong>Conclusion: </strong>In ACS patients, antidepressants do not affect mortality, but can reduce the incidence of myocardial reinfarction.</p>","PeriodicalId":6889,"journal":{"name":"Acta medica Indonesiana","volume":"56 4","pages":"557-562"},"PeriodicalIF":0.7000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta medica Indonesiana","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Acute coronary syndrome (ACS) and depression are related to each other. Detection and proper treatment of these conditions can improve functional ability and quality of life. However, there is still controversy in this population regarding the use, safety, and efficacy of antidepressant pharmacotherapy. This evidence-based case report (EBCR) aims to determine the role of antidepressants in acute coronary syndrome patients.
Methods: Literature searching was performed using online databases such as EBSCO, Embase, PubMed, ClinicalKey, and ScienceDirect according to clinical questions. The studies were selected based on the suitability of the inclusion and exclusion criteria followed by critical appraisal.
Results: In patients with ACS, antidepressants do not affect mortality but may reduce rehospitalization. In patients with ACS and depression who received antidepressants, there is a reduced risk of myocardial infarction (MI) recurrence. In post-ACS patients, the use of antidepressants is associated with a reduced risk of recurrent MI.
Conclusion: In ACS patients, antidepressants do not affect mortality, but can reduce the incidence of myocardial reinfarction.
期刊介绍：
Acta Medica Indonesiana – The Indonesian Journal of Internal Medicine is an open accessed online journal and comprehensive peer-reviewed medical journal published by the Indonesian Society of Internal Medicine since 1968. Our main mission is to encourage the novel and important science in the clinical area in internal medicine. We welcome authors for original articles (research), review articles, interesting case reports, special articles, clinical practices, and medical illustrations that focus on the clinical area of internal medicine. Subjects suitable for publication include, but are not limited to the following fields of: -Allergy and immunology -Emergency medicine -Cancer and stem cells -Cardiovascular -Endocrinology and Metabolism -Gastroenterology -Gerontology -Hematology -Hepatology -Tropical and Infectious Disease -Virology -Internal medicine -Psychosomatic -Pulmonology -Rheumatology -Renal and Hypertension -Thyroid
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