Right Ventricular Outflow Tract Obstruction: Transcatheter Correction in Tetralogy of Fallot: A Pilot Study

IF 2.1 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS American Journal of Cardiology Pub Date : 2025-01-24 DOI:10.1016/j.amjcard.2025.01.013
Asit Das DNB , Shubham Tewary DM , Debdatta Kar DM , Gaurav Lakhani DM , Nur Nabab Mollah DM , Srirupa Mandal MD
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Abstract

A total of 35 patients completed the study. Mean age was 19.8 (±4.2) years, with a male-to-female ratio of 4:3. A total of 25 patients had uncorrected TOF, and 10 had undergone intracardiac repair. After the procedure, patients with uncorrected TOF showed a significant increase in oxygen saturation from 84.7% (±1.4%) to 94.6% (±1.2%). Procedural success was 91.4%, with 3 patients experiencing significant restenosis. No procedural complications were observed. There were no arrhythmic events until the first year of follow-up. At 1-year follow-up, the mean RVOT pressure gradient was significantly decreased, and all patients remained symptom-free. In conclusion, combined balloon pulmonic valvuloplasty and conal artery occlusion is a safe and effective method for alleviating RVOT obstruction in patients with TOF, showing promising intermediate-term outcomes with minimal complications.
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法洛四联症右心室流出道梗阻:经导管矫正:一项初步研究。
本研究评估了经导管入路对法洛四联症(TOF)患者(包括未纠正和心脏内修复(ICR)再狭窄)使用非顺应性球囊扩张和锥形动脉闭塞联合缓解右心室流出道(RVOT)阻塞的效果。一项前瞻性研究于2022年1月至2023年6月进行,包括40例年龄在12岁以上的TOF RVOT梗阻症状患者。排除标准包括中度至重度肺反流。该手术包括两个步骤:不合规的RVOT球囊扩张和使用酒精或线圈或两者同时使用的圆锥动脉栓塞。术前、术后和1年随访时分别进行临床和超声心动图评估。35名患者完成了这项研究。平均年龄19.8(±4.2)岁,男女比例为4:3。25例患者未矫正TOF, 10例为icr后TOF。术后,未矫正患者的血氧饱和度从84.7(±1.4)%显著增加到94.6(±1.2)%。手术成功率为91.4%,3例患者出现明显的再狭窄。无手术并发症。随访1年无心律失常发生。在1年的随访中,平均RVOT压力梯度显著降低,所有患者均无症状。总之,球囊肺动脉瓣成形术联合锥形动脉闭塞术是一种安全有效的缓解TOF患者RVOT阻塞的方法,具有良好的中期预后和最小的并发症。
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来源期刊
American Journal of Cardiology
American Journal of Cardiology 医学-心血管系统
CiteScore
4.00
自引率
3.60%
发文量
698
审稿时长
33 days
期刊介绍: Published 24 times a year, The American Journal of Cardiology® is an independent journal designed for cardiovascular disease specialists and internists with a subspecialty in cardiology throughout the world. AJC is an independent, scientific, peer-reviewed journal of original articles that focus on the practical, clinical approach to the diagnosis and treatment of cardiovascular disease. AJC has one of the fastest acceptance to publication times in Cardiology. Features report on systemic hypertension, methodology, drugs, pacing, arrhythmia, preventive cardiology, congestive heart failure, valvular heart disease, congenital heart disease, and cardiomyopathy. Also included are editorials, readers'' comments, and symposia.
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