Giant Solitary Fibrous Tumor of the Retropharyngeal Space: A Case Report and Review of the Literature.

Bingwan Dong, Enmin Zhao, Feng Wen
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Abstract

Solitary fibrous tumor (SFT) is an uncommon spindle cell neoplasm, which generally arises from the pleura. There have been documented a number of extrapleural origins including the head and neck in the literature. It is emphasized to make a diagnosis in a rare location such as the retropharyngeal space. We present a case of a 54-year-old man diagnosed with giant solitary retropharyngeal SFT. Clinical symptoms were pharyngeal foreign body sensation and dysphagia associated with dyspnea. Physical examination showed a sizable submucosal mass under the posterior pharyngeal wall, which partially obstructed the upper aerodigestive tract. With radiologic images to evaluate the dimension and relationship with surrounding structures, the tumor was surgically removed en bloc via a transcervical approach. The histology and immunohistochemistry play a crucial role in differential diagnosis. Complete surgical excision is an alternative and curative strategy.

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咽后间隙巨型孤立纤维性肿瘤:病例报告和文献综述。
孤立性纤维性肿瘤(SFT)是一种罕见的梭形细胞肿瘤,通常起源于胸膜。文献中记载了许多胸膜外起源,包括头部和颈部。它强调在一个罕见的位置,如咽后间隙作出诊断。我们报告一个54岁男性的病例,诊断为巨大的孤立性咽后SFT。临床表现为咽部异物感、吞咽困难伴呼吸困难。体格检查显示咽后壁下有一相当大的粘膜下肿块,部分阻塞上呼吸道。通过影像学检查评估肿瘤的大小及与周围结构的关系,经颈入路手术切除肿瘤。组织学和免疫组织化学在鉴别诊断中起着至关重要的作用。完全手术切除是另一种治疗策略。
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