Intestinal Obstruction and Neurotoxicity Associated With Water Bead Ingestion.

IF 6.4 2区 医学 Q1 PEDIATRICS Pediatrics Pub Date : 2025-02-01 DOI:10.1542/peds.2023-065575
Ashley Haugen, Elizabeth Friedman, Irina Duff
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Abstract

Water beads are superabsorbent polymer balls. They were originally marketed for agricultural and decorative applications and are now sold as sensory toys. They can be harmful to children in 2 ways. Upon ingestion, water beads absorb liquid and, because they can increase in volume by more than a hundredfold, intestinal obstruction can result. In addition, they are made of polymerized acrylamide monomer. Acrylamide monomer can be toxic at high levels. Here, we present a case of intestinal obstruction in the setting of water bead ingestion temporarily associated with signs of neurotoxicity. The patient presented to the emergency department at 13 months of age with vomiting, lethargy, weight loss over several weeks, insomnia, and facial dermatitis. Due to worsening clinical signs and imaging findings suggestive of intestinal obstruction, she underwent an exploratory laparotomy. A mass consisting of water beads was removed from the distal small intestine. After removal of the mass, the patient's facial dermatitis resolved; however, the patient's speech, gross and fine motor, sensory, and neurological functions continued to worsen. After reevaluation, a second surgical procedure led to removal of multiple fragments of water bead material from the patient's large intestine. This case highlights the potential dangers of acrylamide in consumer products that may be accessible to children.

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与水珠摄入有关的肠梗阻和神经毒性。
水珠是高吸水性聚合物球。它们最初用于农业和装饰应用,现在作为感官玩具出售。它们可能在两个方面对儿童有害。一旦摄入,水珠会吸收液体,因为它们的体积会增加一百倍以上,会导致肠梗阻。此外,它们是由单体丙烯酰胺聚合而成。丙烯酰胺单体在高水平时是有毒的。在这里,我们提出一个病例的肠梗阻设置水珠摄入暂时与神经毒性的迹象。患者13个月大时因呕吐、嗜睡、数周体重减轻、失眠和面部皮炎就诊于急诊科。由于恶化的临床症状和影像学发现提示肠梗阻,她接受了探查性剖腹手术。从远端小肠中取出一团由水珠组成的肿块。肿块切除后,患者面部皮炎消退;然而,患者的语言、粗大和精细运动、感觉和神经功能继续恶化。在重新评估后,第二次手术从患者的大肠中取出了多个水珠碎片。这一案例凸显了儿童可能接触到的消费品中丙烯酰胺的潜在危险。
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来源期刊
Pediatrics
Pediatrics 医学-小儿科
CiteScore
12.80
自引率
5.00%
发文量
791
审稿时长
2-3 weeks
期刊介绍: The Pediatrics® journal is the official flagship journal of the American Academy of Pediatrics (AAP). It is widely cited in the field of pediatric medicine and is recognized as the leading journal in the field. The journal publishes original research and evidence-based articles, which provide authoritative information to help readers stay up-to-date with the latest developments in pediatric medicine. The content is peer-reviewed and undergoes rigorous evaluation to ensure its quality and reliability. Pediatrics also serves as a valuable resource for conducting new research studies and supporting education and training activities in the field of pediatrics. It aims to enhance the quality of pediatric outpatient and inpatient care by disseminating valuable knowledge and insights. As of 2023, Pediatrics has an impressive Journal Impact Factor (IF) Score of 8.0. The IF is a measure of a journal's influence and importance in the scientific community, with higher scores indicating a greater impact. This score reflects the significance and reach of the research published in Pediatrics, further establishing its prominence in the field of pediatric medicine.
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