A 58-Year-Old Woman With Urticaria, Fever, and Joint Pain

JAMA Pub Date : 2025-01-29 DOI:10.1001/jama.2024.28316
Hanna Bonnekoh, Melba Munoz, Pavel Kolkhir
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Abstract

A 58-year-old woman with no allergies or rheumatic disease had a 2-year history of spontaneous wheals that occurred daily, accompanied by pruritus, arthralgia, and intermittent fevers; the wheals resolved after several hours without residual hyperpigmentation or bruising. C-reactive protein level was elevated, and skin biopsy showed dermal neutrophilic infiltration. What is the diagnosis and what would you do next?
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58岁女性,伴有荨麻疹、发热和关节疼痛
一名58岁女性,无过敏或风湿病,每日发生自发性风疹2年,伴有瘙痒、关节痛和间歇性发热;几个小时后,纹样消失,没有残留的色素沉着或瘀伤。c反应蛋白水平升高,皮肤活检显示真皮中性粒细胞浸润。诊断结果是什么,接下来你会怎么做?
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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