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With Nearsightedness in Children on the Rise, Experts Push for Outdoor Time, Disease Designation 儿童近视呈上升趋势,专家呼吁增加户外活动时间并指定疾病名称
Pub Date : 2024-10-25 DOI: 10.1001/jama.2024.21043
Kate Schweitzer
This Medical News article discusses new research on global trends in nearsightedness, possible ways to prevent and treat it, and calls to classify it as a disease.
这篇医学新闻文章讨论了有关全球近视趋势的新研究、预防和治疗近视的可能方法以及将近视归为一种疾病的呼吁。
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引用次数: 0
Study: MMR Vaccine Protection Wanes Slightly Over Time. 研究:麻腮风疫苗的保护作用随时间略有减弱。
Pub Date : 2024-10-25 DOI: 10.1001/jama.2024.21822
Samantha Anderer
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引用次数: 0
Few Patients Receive Testing After Abnormal Urine Protein Results. 尿蛋白结果异常后接受检测的患者寥寥无几。
Pub Date : 2024-10-25 DOI: 10.1001/jama.2024.21826
Samantha Anderer
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引用次数: 0
Bright Light Therapy Not Effective for Major Depressive Disorder. 强光疗法对重度抑郁症无效
Pub Date : 2024-10-25 DOI: 10.1001/jama.2024.21825
Samantha Anderer
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引用次数: 0
HHS Will Provide Free US-Made COVID-19 Tests to Households. HHS 将为家庭免费提供美国制造的 COVID-19 检测试剂。
Pub Date : 2024-10-25 DOI: 10.1001/jama.2024.21819
Samantha Anderer
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引用次数: 0
Pertussis Cases Are Surging This Year-Here's Why. 今年百日咳病例激增--原因何在?
Pub Date : 2024-10-25 DOI: 10.1001/jama.2024.22533
Rita Rubin
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引用次数: 0
Study: Redlining Linked With Shorter Life Expectancy. 研究报告红线与预期寿命缩短有关。
Pub Date : 2024-10-25 DOI: 10.1001/jama.2024.21824
Samantha Anderer
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引用次数: 0
Study Cautions Against Mouth Taping for Patients With Sleep Apnea. 研究提醒睡眠呼吸暂停患者不要使用口腔绑带。
Pub Date : 2024-10-25 DOI: 10.1001/jama.2024.21820
Samantha Anderer
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引用次数: 0
Early, Individualized Recommendations for Hospitalized Patients With Acute Kidney Injury: A Randomized Clinical Trial. 针对急性肾损伤住院患者的早期个性化建议:随机临床试验
Pub Date : 2024-10-25 DOI: 10.1001/jama.2024.22718
Abinet M Aklilu,Steven Menez,Megan L Baker,Dannielle Brown,Katie K Dircksen,Kisha A Dunkley,Simon Correa Gaviria,Salia Farrokh,Sophia C Faulkner,Charles Jones,Bashar A Kadhim,Dustin Le,Fan Li,Amrita Makhijani,Melissa Martin,Dennis G Moledina,Claudia Coronel-Moreno,Kyle D O'Connor,Kyra Shelton,Kristina Shvets,Nityasree Srialluri,Jia Wei Tan,Jeffrey M Testani,Celia P Corona-Villalobos,Yu Yamamoto,Chirag R Parikh,F Perry Wilson,
ImportanceAcute kidney injury (AKI) is a common complication during hospitalization and is associated with adverse outcomes.ObjectiveTo evaluate whether diagnostic and therapeutic recommendations sent by a kidney action team through the electronic health record improve outcomes among patients hospitalized with AKI compared with usual care.Design, Setting, and ParticipantsRandomized clinical trial conducted at 7 hospitals in 2 health systems: in New Haven, Bridgeport, New London, and Waterbury, Connecticut, and Westerly, Rhode Island; and in Baltimore, Maryland. Hospitalized patients with AKI were randomized between October 29, 2021, and February 8, 2024. Final follow-up occurred February 22, 2024.InterventionAn alert about AKI was sent to the kidney action team, consisting of a study physician and study pharmacist, which sent personalized recommendations through the electronic health record in 5 major categories (diagnostic testing, volume, potassium, acid base, and medications) within 1 hour of AKI detection. The note was immediately visible to anyone with access to the electronic health record. Randomization to the intervention or usual care occurred after the recommendations were generated, but the note was only delivered to clinicians of patients randomized to the intervention group.Main Outcomes and MeasuresThe primary outcome was a composite outcome consisting of AKI progression to a higher stage of AKI, dialysis, or mortality occurring while the patient remained hospitalized and within 14 days from randomization.ResultsOf the 4003 patients randomized (median age, 72 years [IQR, 61-81 years), 1874 (47%) were female and 931 (23%) were Black patients. The kidney action team made 14 539 recommendations, with a median of 3 (IQR, 2-5) per patient. The primary outcome occurred in 19.8% of the intervention group and in 18.4% in the usual care group (difference, 1.4%, 95% CI, -1.1% to 3.8,% P = .28). Of 6 secondary outcomes, only 1 secondary outcome, rates of recommendation implementation, significantly differed between the 2 groups: 2459 of 7270 recommendations (33.8%) were implemented in the intervention group and 1766 of 7269 undelivered recommendations (24.3%) were implemented in the usual care group within 24 hours (difference, 9.5%; 95% CI, 8.1% to 11.0%).Conclusions and RelevanceAmong patients hospitalized with AKI, recommendations from a kidney action team did not significantly reduce the composite outcome of worsening AKI stage, dialysis, or mortality, despite a higher rate of recommendation implementation in the intervention group than in the usual care group.Trial RegistrationClinicalTrials.gov Identifier: NCT04040296.
重要性急性肾损伤(AKI)是住院期间常见的并发症,与不良预后有关。目的评估与常规护理相比,肾脏行动小组通过电子健康记录发送的诊断和治疗建议是否能改善急性肾损伤住院患者的预后。设计、设置和参与者随机临床试验在两个医疗系统的 7 家医院进行:康涅狄格州纽黑文、布里奇波特、新伦敦、沃特伯里和罗德岛韦斯特利;马里兰州巴尔的摩。住院的 AKI 患者在 2021 年 10 月 29 日至 2024 年 2 月 8 日期间随机接受治疗。由一名研究医生和一名研究药剂师组成的肾脏行动小组收到 AKI 警报后,会在发现 AKI 的 1 小时内通过电子健康记录发送 5 大类个性化建议(诊断检测、血容量、血钾、酸碱度和药物)。任何可以访问电子病历的人都可以立即看到该记录。主要结果和测量指标主要结果是综合结果,包括 AKI 进展到更高阶段的 AKI、透析或死亡,发生在患者住院期间和随机分组后 14 天内。结果在 4003 名随机分组的患者中(中位年龄 72 岁 [IQR,61-81 岁]),1874 名(47%)为女性,931 名(23%)为黑人患者。肾脏行动小组提出了 14 539 项建议,每名患者的建议中位数为 3 项(IQR,2-5 项)。19.8%的干预组和18.4%的常规护理组出现了主要结果(差异为1.4%,95% CI,-1.1%至3.8%,P = .28)。在 6 项次要结果中,只有 1 项次要结果(建议执行率)在两组之间存在显著差异:干预组在 7270 项建议中执行了 2459 项(33.8%),而常规护理组在 7269 项未交付建议中执行了 1766 项(24.3%)(差异,9.5%;95% CI,8.1% 至 11.0%)。结论和相关性在住院的 AKI 患者中,尽管干预组的建议实施率高于常规护理组,但肾脏行动小组的建议并未显著降低 AKI 阶段恶化、透析或死亡率的综合结果:NCT04040296。
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引用次数: 0
AAP Issues First Opioid Prescribing Guideline for Children. 美国医学会首次发布儿童阿片类药物处方指南。
Pub Date : 2024-10-25 DOI: 10.1001/jama.2024.21821
Samantha Anderer
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引用次数: 0
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