Corrigendum to “Applying molecular hybridization to design a new class of pyrazolo[3,4-d] pyrimidines as Src inhibitors active in hepatocellular carcinoma” [Eur. J. Med. Chem. 280 (2024) 116929]

IF 5.9 2区 医学 Q1 CHEMISTRY, MEDICINAL European Journal of Medicinal Chemistry Pub Date : 2025-03-15 Epub Date: 2025-01-30 DOI:10.1016/j.ejmech.2025.117285
Salvatore Di Maria , Raffaele Passannanti , Federica Poggialini , Chiara Vagaggini , Alessia Serafinelli , Elena Bianchi , Paolo Governa , Lorenzo Botta , Giovanni Maga , Emmanuele Crespan , Fabrizio Manetti , Elena Dreassi , Francesca Musumeci , Anna Carbone , Silvia Schenone
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“应用分子杂交技术设计一类新的吡唑[3,4-d]嘧啶作为肝细胞癌Src抑制剂”的更正[欧洲]。医学与化学杂志,280 (2024)116929]
表1显示了由格式问题引起的几个错误。此外,我们注意到图3中化合物7c的结构存在一个错误。吡唑氮被甲基取代,而不是2-氯-2-苯乙基链。我们现在已经修正了结构。这些修正不会改变结论或工作的总体发现。对于由此造成的不便,作者表示歉意。图3和表1的修正版本如下所示。表1。氨基噻唑 7a-h 和咪唑 8a,b 对Src的酶活性。下载:下载高分辨率图片(289KB)下载:下载全尺寸图片3 . 7d-h优化研究。
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来源期刊
CiteScore
11.70
自引率
9.00%
发文量
863
审稿时长
29 days
期刊介绍: The European Journal of Medicinal Chemistry is a global journal that publishes studies on all aspects of medicinal chemistry. It provides a medium for publication of original papers and also welcomes critical review papers. A typical paper would report on the organic synthesis, characterization and pharmacological evaluation of compounds. Other topics of interest are drug design, QSAR, molecular modeling, drug-receptor interactions, molecular aspects of drug metabolism, prodrug synthesis and drug targeting. The journal expects manuscripts to present the rational for a study, provide insight into the design of compounds or understanding of mechanism, or clarify the targets.
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