Corrigendum to “Applying molecular hybridization to design a new class of pyrazolo[3,4-d] pyrimidines as Src inhibitors active in hepatocellular carcinoma” [Eur. J. Med. Chem. 280 (2024) 116929]
Salvatore Di Maria, Raffaele Passannanti, Federica Poggialini, Chiara Vagaggini, Alessia Serafinelli, Elena Bianchi, Paolo Governa, Lorenzo Botta, Giovanni Maga, Emmanuele Crespan, Fabrizio Manetti, Elena Dreassi, Francesca Musumeci, Anna Carbone, Silvia Schenone
{"title":"Corrigendum to “Applying molecular hybridization to design a new class of pyrazolo[3,4-d] pyrimidines as Src inhibitors active in hepatocellular carcinoma” [Eur. J. Med. Chem. 280 (2024) 116929]","authors":"Salvatore Di Maria, Raffaele Passannanti, Federica Poggialini, Chiara Vagaggini, Alessia Serafinelli, Elena Bianchi, Paolo Governa, Lorenzo Botta, Giovanni Maga, Emmanuele Crespan, Fabrizio Manetti, Elena Dreassi, Francesca Musumeci, Anna Carbone, Silvia Schenone","doi":"10.1016/j.ejmech.2025.117285","DOIUrl":null,"url":null,"abstract":"<strong>Table 1</strong> showed several errors originated from the formatting issue. In addition, we noted a mistake in the structure of compound <strong>7c</strong> reported in <strong>Fig. 3</strong>. The pyrazole nitrogen is substituted by a methyl group instead of 2-chloro-2-phenylethyl chain. We have now corrected the structure. These corrections do not alter the conclusions or the overall findings of the work. The authors would like to apologise for any inconvenience caused. The corrected version of <strong>Fig. 3</strong> and <strong>Table 1</strong> is shown below.<span><span><span><p><span>Table 1</span>. Enzymatic activity of aminothiazoles 7a-h and imidazoles 8a,b towards Src.</p></span></span><img alt=\"\" height=\"956\" src=\"https://ars.els-cdn.com/content/image/1-s2.0-S0223523425000509-fx1.jpg\"/></span><span><figure><span><img alt=\"\" aria-describedby=\"cap0015\" height=\"357\" src=\"https://ars.els-cdn.com/content/image/1-s2.0-S0223523425000509-fx2.jpg\"/><ol><li><span><span>Download: <span>Download high-res image (289KB)</span></span></span></li><li><span><span>Download: <span>Download full-size image</span></span></span></li></ol></span><span><span><p>Fig. 3 Optimization study affording <strong>7d-h</strong>.</p></span></span></figure></span>","PeriodicalId":314,"journal":{"name":"European Journal of Medicinal Chemistry","volume":"129 1","pages":""},"PeriodicalIF":6.0000,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Medicinal Chemistry","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.ejmech.2025.117285","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
引用次数: 0
Abstract
Table 1 showed several errors originated from the formatting issue. In addition, we noted a mistake in the structure of compound 7c reported in Fig. 3. The pyrazole nitrogen is substituted by a methyl group instead of 2-chloro-2-phenylethyl chain. We have now corrected the structure. These corrections do not alter the conclusions or the overall findings of the work. The authors would like to apologise for any inconvenience caused. The corrected version of Fig. 3 and Table 1 is shown below.
Table 1. Enzymatic activity of aminothiazoles 7a-h and imidazoles 8a,b towards Src.
期刊介绍:
The European Journal of Medicinal Chemistry is a global journal that publishes studies on all aspects of medicinal chemistry. It provides a medium for publication of original papers and also welcomes critical review papers.
A typical paper would report on the organic synthesis, characterization and pharmacological evaluation of compounds. Other topics of interest are drug design, QSAR, molecular modeling, drug-receptor interactions, molecular aspects of drug metabolism, prodrug synthesis and drug targeting. The journal expects manuscripts to present the rational for a study, provide insight into the design of compounds or understanding of mechanism, or clarify the targets.