Characteristics of the 2023-2024 Mycoplasma pneumoniae epidemic in adults, Southeast France

IF 1.7 Q4 INFECTIOUS DISEASES IJID regions Pub Date : 2025-03-01 Epub Date: 2024-12-18 DOI:10.1016/j.ijregi.2024.100548

Anna Wolski , Sophie Edouard , Barbara Melo , Philippe Lavrard , Sébastien Cortaredona , Justine Punturo , Aurélia Bordais , Sami Hraiech , Florence Fenollar , Jean-Christophe Lagier , Nadim Cassir

{"title":"Characteristics of the 2023-2024 Mycoplasma pneumoniae epidemic in adults, Southeast France","authors":"Anna Wolski , Sophie Edouard , Barbara Melo , Philippe Lavrard , Sébastien Cortaredona , Justine Punturo , Aurélia Bordais , Sami Hraiech , Florence Fenollar , Jean-Christophe Lagier , Nadim Cassir","doi":"10.1016/j.ijregi.2024.100548","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><div>Analysis of current 2023-2024 <em>Mycoplasma pneumoniae</em> (Mp) infection characteristics in adults.</div></div><div><h3>Methods</h3><div>A retrospective case series analysis was performed on <em>Mp</em> polymerase chain reaction-positive adult patients admitted to the University Hospital of Marseille from April 2017 to June 2024. Clinical presentations, treatments, and outcomes were assessed. We compared the epidemiological and clinical characteristics of <em>Mp</em> infections between 2017 and 2022 with the current epidemic.</div></div><div><h3>Results</h3><div>Clinical and radiological characteristics and outcomes of patients with <em>Mp</em> infection did not differ significantly between the current epidemic (N = 108) and the 5 previous years (N = 94), except that patients in the current epidemic required less supplemental oxygen (odds ratio [95% confidence interval] = 0.48 [0.29-0.78]) and were less likely to present with fever on admission (odds ratio [95% confidence interval] = 0.22 [0.10-0.47]). In both periods, more than half of the patients hospitalized with <em>Mp</em> infection required supportive oxygen therapy.</div></div><div><h3>Conclusions</h3><div>During the current 2023-2024 epidemic, more hospital admissions for <em>Mp</em> infection in adults were observed at the University Hospital of Marseille than in the previous 5 years. The clinical characteristics and outcomes of patients with <em>Mp</em> infection did not differ significantly. In our cohort, <em>Mp</em> infection was often severe, regardless of the study period.</div></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":"14 ","pages":"Article 100548"},"PeriodicalIF":1.7000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11773249/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IJID regions","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772707624002170","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/12/18 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}

引用次数: 0

Abstract

Objectives

Analysis of current 2023-2024 Mycoplasma pneumoniae (Mp) infection characteristics in adults.

Methods

A retrospective case series analysis was performed on Mp polymerase chain reaction-positive adult patients admitted to the University Hospital of Marseille from April 2017 to June 2024. Clinical presentations, treatments, and outcomes were assessed. We compared the epidemiological and clinical characteristics of Mp infections between 2017 and 2022 with the current epidemic.

Results

Clinical and radiological characteristics and outcomes of patients with Mp infection did not differ significantly between the current epidemic (N = 108) and the 5 previous years (N = 94), except that patients in the current epidemic required less supplemental oxygen (odds ratio [95% confidence interval] = 0.48 [0.29-0.78]) and were less likely to present with fever on admission (odds ratio [95% confidence interval] = 0.22 [0.10-0.47]). In both periods, more than half of the patients hospitalized with Mp infection required supportive oxygen therapy.

Conclusions

During the current 2023-2024 epidemic, more hospital admissions for Mp infection in adults were observed at the University Hospital of Marseille than in the previous 5 years. The clinical characteristics and outcomes of patients with Mp infection did not differ significantly. In our cohort, Mp infection was often severe, regardless of the study period.

Abstract Image

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

2023-2024年法国东南部成人肺炎支原体流行特征

目的：分析2023-2024年成人肺炎支原体（Mp）感染特点。方法：对2017年4月至2024年6月马赛大学医院Mp聚合酶链反应阳性的成人患者进行回顾性病例系列分析。评估临床表现、治疗和结果。我们将2017 - 2022年Mp感染的流行病学和临床特征与当前疫情进行了比较。结果：本次疫情（N = 108）与前5年（N = 94）相比，Mp感染患者的临床和影像学特征及预后无显著差异，只是本次疫情患者需要补充氧气较少（优势比[95%可信区间]= 0.48[0.29-0.78]），入院时出现发热的可能性较低（优势比[95%可信区间]= 0.22[0.10-0.47]）。在这两个时期，超过一半的Mp感染住院患者需要支持氧治疗。结论：在目前的2023-2024年流行期间，马赛大学医院观察到的成人Mp感染住院人数比前5年多。Mp感染患者的临床特征和预后无显著差异。在我们的队列中，无论研究时间如何，Mp感染通常都很严重。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊