Prevalence of chronic kidney disease in Western Australia, 2010-2020.

IF 2.3 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL BMJ Open Pub Date : 2025-01-28 DOI:10.1136/bmjopen-2024-092320
Kanika Mehta, Sean Randall, Crystal Man Ying Lee, Elizabeth Thomas, Aron Chakera, Kevin Chai, Mohamed Estai, Madison Frith, Delia Hendrie, James Boyd, Suzanne Robinson
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Abstract

Objective: To assess the prevalence and trends of chronic kidney disease (CKD) in Western Australia (WA) from 2010 to 2020 using linked pathology data.

Design: A retrospective observational cohort study using linked de-identified data from WA pathology providers, hospital morbidity records and mortality records.

Setting: A Western Australian population-based study.

Participants: All individuals aged 18 years and older with at least one serum creatinine test.

Primary outcome measure: CKD status as determined by estimated glomerular filtration rate and urine albumin-creatinine ratio.

Results: Analysing data from 2 501 188 individuals, there was a significant increase in age-sex standardised CKD prevalence from 4.7% in 2010 to 6.0% in 2020, with annual average percentage change of 3.0% (95% CI: 2.3% to 3.7%). Prevalence of CKD stages 3 and above was 4.8% in 2020. Higher CKD prevalence was observed in regional and remote areas compared with major cities, and among individuals in the most socioeconomically disadvantaged quintiles. Sensitivity analysis indicated minor impacts from data exclusions and methodological choices.

Conclusions: CKD prevalence in WA has been steadily increasing, reflecting broader Australian trends. The study highlights significant disparities in CKD prevalence based on age, socioeconomic status and geographic remoteness.

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2010-2020年西澳大利亚州慢性肾病患病率
目的:利用相关病理数据评估2010年至2020年西澳大利亚州(WA)慢性肾脏疾病(CKD)的患病率和趋势。设计:一项回顾性观察队列研究,使用来自西澳病理学提供者、医院发病率记录和死亡率记录的相关去识别数据。背景:一项以西澳大利亚人口为基础的研究。参与者:所有年龄在18岁及以上且至少有一次血清肌酐测试的个体。主要结局指标:CKD状态由肾小球滤过率和尿白蛋白-肌酐比值确定。结果:分析2 501 188人的数据,年龄-性别标准化CKD患病率从2010年的4.7%显著增加到2020年的6.0%,年平均百分比变化为3.0% (95% CI: 2.3%至3.7%)。到2020年,CKD 3期及以上的患病率为4.8%。与主要城市相比,在区域和偏远地区以及社会经济最不利的五分之一人群中,CKD患病率较高。敏感性分析显示数据排除和方法选择的影响较小。结论:西澳CKD患病率稳步上升,反映了更广泛的澳大利亚趋势。该研究强调了CKD患病率在年龄、社会经济地位和地理偏远程度上的显著差异。
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来源期刊
BMJ Open
BMJ Open MEDICINE, GENERAL & INTERNAL-
CiteScore
4.40
自引率
3.40%
发文量
4510
审稿时长
2-3 weeks
期刊介绍: BMJ Open is an online, open access journal, dedicated to publishing medical research from all disciplines and therapeutic areas. The journal publishes all research study types, from study protocols to phase I trials to meta-analyses, including small or specialist studies. Publishing procedures are built around fully open peer review and continuous publication, publishing research online as soon as the article is ready.
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