Unusual manifestations of syphilis in HIV.

Abstract

Over the past decade, there has been a significant increase in cases with syphilis and HIV coinfection. Concordant infection with HIV can alter the clinical course and response to treatment in syphilis. Variable and unusual presentations of syphilis in HIV disease can make early diagnosis and treatment challenging. We, herein, report four cases of atypical manifestations of syphilis in patients with HIV coinfection.