Indian Journal of Sexually Transmitted Diseases and AIDS最新文献

Background: Patients with syphilis, who receive appropriate treatment, fail to achieve serological cure and have persistent nontreponemal titers. This study was conducted to analyze the factors associated with serofast stage after the treatment of patients.

Methods: A retrospective study was conducted from January 2019 to June 2022, involving 70 patients with syphilis who were followed up for 12 months using the Venereal Disease Research Laboratory (VDRL) test.

Results: Primary syphilis was observed in 11.4% (8), secondary syphilis in 77.2% (54), and latent syphilis in 11.4% (8) of the patients. The serological cure rates at 3, 6, 9, and 12 months were 10% (7/70), 41.4% (29/70), 50% (35), and 62.8% (44), respectively. Patients <25 years and with higher baseline VDRL titers (>1:16) had a better response to treatment. HIV-positive patients had 1.7-fold higher odds of serological failure compared to HIV-negative patients.

Conclusion: In conclusion, our study underscores the need for tailored approaches to syphilis management and highlights the importance of ongoing research to enhance our understanding of treatment response predictors and optimize patient outcomes.

Context: Vulvar dermatoses include a broad spectrum of inflammatory, infectious, pigmentary, and vascular entities presenting a diagnostic challenge with a significant impact on quality of life (QoL). Dermatoscopy has now become an integral part of the dermatologist's armamentarium. It serves as a useful noninvasive adjunct to clinical examination.

Aims: The aim of the study is to study the clinical, demographic, and dermoscopic features of common vulvar dermatoses.

Materials and methods: A cross-sectional descriptive study was conducted in 100 patients attending the Dermatology, Venerology and Leprosy Out patient Department (DVL OP) with vulvar lesions. For the dermoscopic assessment Dermlite 4, USA dermoscope was used and the pictures were recorded on a smartphone. Vulvar disease QoL index is used to evaluate the QoL at the time of diagnosis.

Statistical analysis used: SPSS software was used for the statistical analysis. P <0.05 was considered statistically significant.

Results: A total of 100 females were diagnosed with vulvar dermatoses with age ranging from 5 years to 70 years. Majority of the females belonged to the age group of 31-40 years with a mean age of 36.9 years. Among 100 patients, 76% (n = 76) were married. Infections (73%) constituted the most common etiology of vulvar dermatoses. Mild-to-moderate impairment is QoL.

Conclusions: This study highlights the importance of enhancing awareness, promoting hygiene education, and incorporating dermoscopy in vulvar dermatology to optimize patient outcomes. We reiterate the impact of vulvar dermatoses on the QoL of the patients.

Vulvar vestibular papillomatosis is a normal anatomical variant of the vulva. It presents with small, shiny papules over the labia minora and the vestibule. However, similar lesions over the labia majora have not been reported yet. Here we are reporting a case of vestibular papillomatosis over the labia majora in a young female mimicking a wart.

Transgender (TG) individuals represent a growing yet underserved community with unique healthcare challenges, particularly their increased vulnerability to sexually transmitted infections. This case series assesses the clinico-epidemiological profile of five TG patients attending the Suraksha clinic at a tertiary hospital in Northern India. Key risk factors include early sexual debut, limited education, and inconsistent substance use. Diagnosed infections include syphilis, genital warts, and anal herpes. Despite access to healthcare, 60% of patients were lost to follow-up. Active surveillance in high-risk areas, along with psychological and medical support, may improve health outcomes by addressing socioeconomic and educational barriers.