The effect of massive liposuction surgery of the abdomen and flanks on insulin and some adipokines

Abstract

Liposuction is one of the most common aesthetic procedures worldwide. Although primarily cosmetic, the effect of liposuction on lipid and carbohydrate metabolism is of interest due to the dynamic role that adipose tissue plays in these processes. However, this effect is not fully understood.

In this study, the impact of massive liposuction procedures (aspiration of more than 5 L volume) from the abdomen and flanks on biochemical parameters, including Leptin, Adiponectin, Resistin, and Insulin, was analysed. Twenty-two candidates were recruited, and the mentioned parameters were measured and compared with their postoperative concentrations three months after the procedure using the Enzyme-Linked Immunosorbent Assay (ELISA) technique.

We found a significant reduction (p value <0.001) in postoperative measurements of Leptin, Resistin, and Insulin, alongside a significant (p value <0.001) increment in Adiponectin levels. These findings indicate a positive impact of the liposuction procedure on lipid and carbohydrate metabolism. The analysis of our study observations suggests that liposuction surgery could play a role in improving metabolism and may serve as a beneficial adjunct in addressing metabolic disorders when combined with diet, exercise, and lifestyle modifications.