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Patient recruitment strategies of the Belgian plastic surgeon: A national anonymous survey 比利时整形外科医生的患者招募策略:一项全国匿名调查
IF 2.4 3区 医学 Q2 SURGERY Pub Date : 2026-01-13 DOI: 10.1016/j.bjps.2026.01.001
Renee De Busser , Amélie Bouteille , Stefaan Callens , Margot Den Hondt , Moustapha Hamdi

Background

Patient recruitment strategies in plastic surgery are diverse, and no overview exists for Belgium. Internationally, word of mouth is the most common method, while social media usage grows.

Purpose

This study aimed to map recruitment methods among Belgian plastic surgeons and explore differences by age and professional location.

Methods

Plastic surgeons practicing in Belgium were included in a prospective survey. An anonymous online questionnaire (LimeSurvey) was distributed and data analysed using SPSS.

Results

Eighteen percent of all Belgian plastic surgeons participated. Referrals and word of mouth were the primary recruitment methods, followed by websites and social media. Referrals were mainly by gynaecologists, dermatologists and GPs. Intra-centre collaboration was most frequent in university and general hospitals (both 74%). Non-surgical and aesthetic procedures were proportionally more common in private clinics, while reconstructive procedures dominated university and general hospitals. Fifty-two percent treated international patients, an average of 15% of practice volume, predominantly aesthetic cases (68%). All surgeons used a website, and 54% were active on social media, primarily Instagram (60%) and Facebook (26%). Social media reached mainly 20- to 40-year-old patients (66%) with aesthetic concerns (62%).

Conclusion

Referrals and word of mouth are the most important recruitment strategies among Belgian plastic surgeons. Social media is increasingly relevant, particularly for younger, international patients and aesthetic surgery. Its growing use raises professional, legal, and ethical challenges, highlighting the need for clearer legislation, awareness, and enforcement strategies with patient safety as central priority.
背景:整形外科的患者招募策略是多种多样的,没有比利时的概述。在国际上,口口相传是最常见的方法,而社交媒体的使用也在增长。目的研究比利时整形外科医生的招募方法,探讨年龄和职业地区的差异。方法对在比利时执业的整形外科医生进行前瞻性调查。采用匿名在线问卷(limessurvey)进行调查,并使用SPSS软件对数据进行分析。结果18%的比利时整形外科医生参与了调查。推荐和口口相传是主要的招聘方式,其次是网站和社交媒体。转介者主要是妇科医生、皮肤科医生和全科医生。中心内合作在大学医院和综合医院最为常见(均为74%)。非手术和美容手术在私人诊所中更为常见,而重建手术在大学和综合医院中占主导地位。52%的人治疗国际患者,平均占业务量的15%,主要是美容病例(68%)。所有的外科医生都使用一个网站,54%的人活跃在社交媒体上,主要是Instagram(60%)和Facebook(26%)。社交媒体接触的主要是20- 40岁的患者(66%),他们关注审美(62%)。结论推荐和口碑是比利时整形外科医生最重要的招聘策略。社交媒体越来越重要,尤其是对年轻的国际患者和美容手术。它的使用日益增加,带来了专业、法律和道德方面的挑战,突出表明需要更明确的立法、意识和执法策略,以患者安全为中心优先事项。
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引用次数: 0
Cholesteatoma in concha-type microtia 胆脂瘤见于甲壳型小鼠
IF 2.4 3区 医学 Q2 SURGERY Pub Date : 2026-01-07 DOI: 10.1016/j.bjps.2025.12.036
Nobuyuki Mitsuhashi , Takatoshi Yotsuyanagi , Ken Yamashita , Shinji Kato , Ayaka Kitada , Minoru Sakuraba

Background

Concha-type microtia with congenital aural stenosis carries a risk of external auditory canal cholesteatoma, which may cause infection and lead to the loss of costal cartilage grafts during auricular reconstruction. However, awareness of this risk among plastic surgeons remains limited. We aimed to review cases of cholesteatoma in concha-type microtia and discuss optimal management strategies.

Methods

We conducted a single-center retrospective review of patients with concha-type or small concha-type microtia and congenital aural stenosis who underwent auricular reconstruction with costal cartilage grafting between January 2018 and December 2021. We identified patients who developed external auditory canal cholesteatoma and analyzed the timing of occurrence, treatment, postoperative complications, graft preservation or removal, and postoperative course (including recurrence).

Results

Among 278 patients with microtia (90 auricles), 83 had concha-type or small concha-type microtia. The mean age at surgery was 11.8 years (range 10 to 24 years; median 11 years), and the cohort comprised 53 males and 30 females. Congenital aural stenosis (<4 mm) was present in 60 auricles, with cholesteatoma occurring in 4 (6.7%). One cholesteatoma was diagnosed preoperatively, two were diagnosed shortly after reconstruction (one required graft removal), and two were diagnosed after reconstruction. All patients underwent cholesteatoma excision and canalplasty. During ≥2 years of follow-up, mild restenosis but no recurrence were observed.

Conclusion

Concha-type microtia with congenital aural stenosis carries a risk of cholesteatoma. Preoperative screening is essential, and excision should precede auricular reconstruction. Vigilance during and after reconstruction, and close collaboration with otolaryngologists, are essential to prevent complications.
先天性耳廓狭窄的耳甲型小耳症有外耳道胆脂瘤的风险,可能引起感染并导致耳廓重建时肋软骨移植物的丢失。然而,整形外科医生对这种风险的认识仍然有限。我们的目的是回顾胆脂瘤在耳甲型小耳蜗的病例,并讨论最佳的管理策略。方法对2018年1月至2021年12月行肋软骨移植耳廓重建术的耳廓型或小耳廓型小耳廓狭窄患者进行单中心回顾性分析。我们确定了发生外耳道胆脂瘤的患者,并分析了发生时间、治疗、术后并发症、移植物保存或切除以及术后病程(包括复发)。结果278例小耳廓(90耳)中,有83例为甲壳型或小甲壳型小耳廓。手术的平均年龄为11.8岁(范围10 - 24岁,中位数11岁),队列包括53名男性和30名女性。先天性耳廓狭窄(4mm) 60例,胆脂瘤4例(6.7%)。1例术前诊断为胆脂瘤,2例重建后不久诊断为胆脂瘤(1例需要移除移植物),2例重建后诊断为胆脂瘤。所有患者均行胆脂瘤切除术和胆管成形术。随访≥2年,轻度再狭窄,无复发。结论先天性耳廓狭窄伴耳甲型小耳有胆脂瘤的危险。术前筛查是必要的,切除应先于耳廓重建。重建期间和重建后保持警惕,并与耳鼻喉科医生密切合作,对预防并发症至关重要。
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引用次数: 0
Harnessing population genetics and animal models to uncover the genetics of skin scarring 利用群体遗传学和动物模型来揭示皮肤疤痕的遗传学。
IF 2.4 3区 医学 Q2 SURGERY Pub Date : 2026-01-01 DOI: 10.1016/j.bjps.2025.11.010
Oscar A. Peña , Marisa Cañadas-Garre , Iona Collins , Nicholas J. Timpson , Paul Martin
Skin wound healing is a complex process that requires the orchestrated response of several different cell types to repair the damaged tissue and restore function. Superficial skin wounds tend to heal within days. However, larger and deeper wounds such as those caused by trauma or surgery generally heal by leaving a scar, which can impact tissue function. Scars can be debilitating, painful, and can significantly impair function. New developments to prevent and treat scarring require a deeper understanding of the cellular and molecular mechanisms associated with wound healing and scarring. Most of our current understanding of the genetics of wound healing comes from studies in animal models. However, population health approaches combined with experimental validation in animal models offer new opportunities to harness natural variability in wound repair outcomes in the population and identify new relevant biology controlling different aspects of repair and scarring in a different way. These approaches have the potential to reveal association between genetic loci and wound phenotypes in humans. Complementary experimental studies in animal models can help to validate these candidate genes and our understanding of the underlying mechanisms. In this non-systematic review, we propose the application of strategies using population health/genetics together with zebrafish models of wounding to specifically study skin scarring. We discuss potential pitfalls and strengths of the combined and complementary use of population health approaches and animal models for the identification and validation of new genes involved in skin repair, and in particular, scarring.
皮肤创面愈合是一个复杂的过程,需要多种不同类型细胞的协调反应来修复受损组织和恢复功能。皮肤表面的伤口往往会在几天内愈合。然而,更大和更深的伤口,如创伤或手术造成的伤口,通常会留下疤痕来愈合,这会影响组织功能。疤痕会使人虚弱、痛苦,并会严重损害身体机能。预防和治疗瘢痕形成的新进展需要对与伤口愈合和瘢痕形成相关的细胞和分子机制有更深入的了解。我们目前对伤口愈合的遗传学的了解大多来自动物模型的研究。然而,人群健康方法与动物模型实验验证相结合,为利用人群中伤口修复结果的自然变异性提供了新的机会,并确定了以不同方式控制修复和瘢痕形成不同方面的新的相关生物学。这些方法有可能揭示遗传位点与人类伤口表型之间的关系。动物模型的补充实验研究可以帮助验证这些候选基因和我们对潜在机制的理解。在这篇非系统综述中,我们建议将群体健康/遗传学策略与斑马鱼损伤模型结合起来专门研究皮肤疤痕。我们讨论了潜在的缺陷和优势,结合和补充使用人群健康方法和动物模型来识别和验证参与皮肤修复的新基因,特别是疤痕。
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引用次数: 0
Orofacial cleft repair: A clinical model for studying genetic contribution to scar severity 口面裂修复:研究疤痕严重程度遗传贡献的临床模型。
IF 2.4 3区 医学 Q2 SURGERY Pub Date : 2026-01-01 DOI: 10.1016/j.bjps.2025.10.044
Rebecca J. Richardson , Kevin Thiessen , Nigel Mercer , Bruce Richard , Yvonne Wren , Jonathan Sandy
Scars resulting from surgical repair of cleft lip and palate provide a unique model in humans for studying factors that affect the severity of scarring. Anatomically, clefts of the lip and palate are consistent in location and are treated surgically with similar methods and timing. This contrasts with the considerably greater variability observed in traumatic injuries, burns or emergency surgical procedures and the scars resulting from these cause tissue damage. Clinical audit protocols for cleft lip and palate ensure that data on outcomes for appearance, function and wellbeing are collected at standard points in a child’s development and are followed-up over time, permitting cross sectional and longitudinal analysis of scarring. Therefore, enhancing our understanding of the impact of genetics and environmental factors on scar severity following surgical repair of clefts can provide information on factors that may be associated with scarring from other insults, where uniform data are not available. Animal models offer opportunities to investigate factors that could influence scar severity and overall repair quality. In this review, we will discuss the possibilities for scarring research in cohorts of children born with cleft defects and the advantages of using different animal models for studying the mechanistic drivers of variation in scar severity.
唇腭裂手术修复后的瘢痕为研究影响瘢痕严重程度的因素提供了一个独特的人体模型。解剖上,唇裂和腭裂在位置上是一致的,用相似的手术方法和时间来治疗。这与在创伤性损伤、烧伤或紧急外科手术中观察到的更大的可变性形成对比,这些造成的疤痕会导致组织损伤。唇腭裂的临床审计方案确保在儿童发育的标准点收集外观,功能和健康结果的数据,并随着时间的推移进行随访,允许对疤痕进行横断面和纵向分析。因此,加强我们对遗传和环境因素对唇腭裂手术修复后瘢痕严重程度的影响的理解,可以提供可能与其他损伤引起的瘢痕相关的因素的信息,在这些方面没有统一的数据。动物模型为研究可能影响疤痕严重程度和整体修复质量的因素提供了机会。在这篇综述中,我们将讨论在先天性腭裂缺陷儿童群体中进行疤痕研究的可能性,以及使用不同动物模型研究疤痕严重程度变化的机制驱动因素的优势。
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引用次数: 0
Evaluating the role of the ‘Accessible Novel Solutions for Widespread Emergency Reconstructive Surgery’ (ANSWERS) 3D-printed perineal training model for conflict-related sexual violence injuries 评估“广泛紧急重建手术的无障碍新解决方案”(ANSWERS) 3d打印会阴培训模型对与冲突有关的性暴力伤害的作用。
IF 2.4 3区 医学 Q2 SURGERY Pub Date : 2026-01-01 DOI: 10.1016/j.bjps.2025.11.051
Stephen R. Ali , HRH The Duchess of Edinburgh , Gloire Byabene , Carys Edwards , Beth Norman , Octavian Parkes , Hari Arora , Denis Mukwege , Iain S. Whitaker

Introduction

Conflict-related sexual violence (CRSV) causes considerable physical and psychological harm, often leading to complex urogenital injuries that require specialised reconstructive surgery. Despite the growing global demand for specialised surgical care, access to niche specialities and training resources remain limited, particularly in high-conflict and resource-constrained areas. This study evaluates the effectiveness of the Accessible Novel Solutions for Widespread Emergency Reconstructive Surgery (ANSWERS) 3D-printed model, developed in collaboration with the Panzi Foundation, as a training tool for urogenital fistula repair associated with CRSV.

Methods

Conducted at Panzi Hospital in the Democratic Republic of Congo, this study employed a cross-sectional survey design involving 13 healthcare professionals. Participants engaged in hands-on practice with the 3D-printed model, creating and repairing simulated defects to closely replicate CRSV injuries. The survey assessed the model’s anatomical fidelity, usability and impact on surgical preparedness, incorporating quantitative ratings and qualitative feedback.

Results

Our findings revealed strong support for the model's training value, with most participants reporting increased confidence in their technical skills. Areas for improvement due to limitations of anatomical detail and material durability were noted. Qualitative insights indicated that integrating the Panzi score—a classification system for fistula severity—and augmented reality or extended reality technology could enhance the model's relevance and interactivity.

Conclusion

The study highlights the use of the ANSWERS 3D-printed model in building competency-based training protocols in CRSV care. Future refinements in the multilayered materials, novel bioengineering approaches to enhance biomimicry, anatomical accuracy based on CT scans and Panzi score classifications hold great potential. Ultimately, digital integrations could lead to the development of a standardised, immersive training curriculum that aligns with Panzi Hospital’s holistic approach, improving surgical outcomes for CRSV survivors globally.
与冲突有关的性暴力(CRSV)造成相当大的身体和心理伤害,往往导致复杂的泌尿生殖系统损伤,需要专门的重建手术。尽管全球对专业外科护理的需求不断增长,但获得利基专业和培训资源的机会仍然有限,特别是在高冲突和资源有限的地区。本研究评估了与Panzi基金会合作开发的广泛紧急重建手术无障碍新解决方案(ANSWERS) 3d打印模型的有效性,该模型作为与CRSV相关的泌尿生殖瘘修复的培训工具。方法:本研究在刚果民主共和国Panzi医院进行,采用横断面调查设计,涉及13名卫生保健专业人员。参与者参与了3d打印模型的动手实践,创建和修复模拟缺陷,以紧密复制CRSV损伤。该调查评估了模型的解剖保真度、可用性和对手术准备的影响,包括定量评分和定性反馈。结果:我们的研究结果显示了对模型训练价值的强有力支持,大多数参与者报告说他们对自己的技术技能增加了信心。指出了由于解剖细节和材料耐久性的限制而需要改进的领域。定性分析表明,将Panzi评分(瘘管严重程度的分类系统)与增强现实或扩展现实技术相结合,可以增强模型的相关性和交互性。结论:该研究强调了在CRSV护理中使用ANSWERS 3d打印模型构建基于能力的培训协议。未来多层材料的改进、增强仿生学的新型生物工程方法、基于CT扫描和Panzi评分分类的解剖准确性都具有巨大的潜力。最终,数字整合可能导致标准化、沉浸式培训课程的开发,该课程与Panzi医院的整体方法相一致,从而改善全球CRSV幸存者的手术结果。
{"title":"Evaluating the role of the ‘Accessible Novel Solutions for Widespread Emergency Reconstructive Surgery’ (ANSWERS) 3D-printed perineal training model for conflict-related sexual violence injuries","authors":"Stephen R. Ali ,&nbsp;HRH The Duchess of Edinburgh ,&nbsp;Gloire Byabene ,&nbsp;Carys Edwards ,&nbsp;Beth Norman ,&nbsp;Octavian Parkes ,&nbsp;Hari Arora ,&nbsp;Denis Mukwege ,&nbsp;Iain S. Whitaker","doi":"10.1016/j.bjps.2025.11.051","DOIUrl":"10.1016/j.bjps.2025.11.051","url":null,"abstract":"<div><h3>Introduction</h3><div>Conflict-related sexual violence (CRSV) causes considerable physical and psychological harm, often leading to complex urogenital injuries that require specialised reconstructive surgery. Despite the growing global demand for specialised surgical care, access to niche specialities and training resources remain limited, particularly in high-conflict and resource-constrained areas. This study evaluates the effectiveness of the Accessible Novel Solutions for Widespread Emergency Reconstructive Surgery (ANSWERS) 3D-printed model, developed in collaboration with the Panzi Foundation, as a training tool for urogenital fistula repair associated with CRSV.</div></div><div><h3>Methods</h3><div>Conducted at Panzi Hospital in the Democratic Republic of Congo, this study employed a cross-sectional survey design involving 13 healthcare professionals. Participants engaged in hands-on practice with the 3D-printed model, creating and repairing simulated defects to closely replicate CRSV injuries. The survey assessed the model’s anatomical fidelity, usability and impact on surgical preparedness, incorporating quantitative ratings and qualitative feedback.</div></div><div><h3>Results</h3><div>Our findings revealed strong support for the model's training value, with most participants reporting increased confidence in their technical skills. Areas for improvement due to limitations of anatomical detail and material durability were noted. Qualitative insights indicated that integrating the Panzi score—a classification system for fistula severity—and augmented reality or extended reality technology could enhance the model's relevance and interactivity.</div></div><div><h3>Conclusion</h3><div>The study highlights the use of the ANSWERS 3D-printed model in building competency-based training protocols in CRSV care. Future refinements in the multilayered materials, novel bioengineering approaches to enhance biomimicry, anatomical accuracy based on CT scans and Panzi score classifications hold great potential. Ultimately, digital integrations could lead to the development of a standardised, immersive training curriculum that aligns with Panzi Hospital’s holistic approach, improving surgical outcomes for CRSV survivors globally.</div></div>","PeriodicalId":50084,"journal":{"name":"Journal of Plastic Reconstructive and Aesthetic Surgery","volume":"112 ","pages":"Pages 96-105"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145777007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A better understanding and outcomes for wounds and scars: 25 Years of the Scar Free Foundation 对伤口和疤痕更好的理解和结果:无疤痕基金会25年
IF 2.4 3区 医学 Q2 SURGERY Pub Date : 2026-01-01 DOI: 10.1016/j.bjps.2025.12.027
Jason Wong (JPRAS Deputy Editor), Richard Nugee (Lt. Gen., Chief Executive)
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引用次数: 0
From patient to partner: Crowdsourcing and digital innovations reshaping scar research and scar care management 从患者到合作伙伴:众包和数字创新重塑疤痕研究和疤痕护理管理。
IF 2.4 3区 医学 Q2 SURGERY Pub Date : 2026-01-01 DOI: 10.1016/j.bjps.2025.10.024
K.J.P. Maertens , T. Demarbaix , J. Meirte , U. Van Daele , P. Moortgat
Traditional scar research has historically prioritized clinician-driven outcomes, often neglecting patient-identified needs and real-world experiences. This narrative review synthesizes developments in patient-powered innovation across scar research, drawing from the last decade of literature on patient-reported outcome measures (PROMs), real-world data, digital health tools, and participatory models. Increased adoption of PROMs (e.g., Patient and Observer Scar Assessment Scale 3.0 and SCAR-Q), crowdsourced initiatives, and digital tools (e.g., ScarPath, smartphone apps, and AI-based assessments) are transforming scar research and management by centering patient priorities. Patient-powered approaches—through digital tools, crowdsourcing, and participatory research—are reshaping scar care by promoting real-world engagement and more meaningful, personalized outcomes.
传统的疤痕研究历来优先考虑临床驱动的结果,往往忽略了患者确定的需求和现实世界的经验。这篇叙述性综述综合了疤痕研究中患者驱动创新的发展,借鉴了过去十年关于患者报告结果测量(PROMs)、现实世界数据、数字健康工具和参与式模型的文献。越来越多地采用PROMs(例如,患者和观察者疤痕评估量表3.0和Scar - q)、众包计划和数字工具(例如,ScarPath、智能手机应用程序和基于人工智能的评估),通过集中患者的优先事项,正在改变疤痕研究和管理。通过数字工具、众包和参与式研究,以患者为动力的方法正在通过促进现实世界的参与和更有意义的个性化结果来重塑疤痕护理。
{"title":"From patient to partner: Crowdsourcing and digital innovations reshaping scar research and scar care management","authors":"K.J.P. Maertens ,&nbsp;T. Demarbaix ,&nbsp;J. Meirte ,&nbsp;U. Van Daele ,&nbsp;P. Moortgat","doi":"10.1016/j.bjps.2025.10.024","DOIUrl":"10.1016/j.bjps.2025.10.024","url":null,"abstract":"<div><div>Traditional scar research has historically prioritized clinician-driven outcomes, often neglecting patient-identified needs and real-world experiences. This narrative review synthesizes developments in patient-powered innovation across scar research, drawing from the last decade of literature on patient-reported outcome measures (PROMs), real-world data, digital health tools, and participatory models. Increased adoption of PROMs (e.g., Patient and Observer Scar Assessment Scale 3.0 and SCAR-Q), crowdsourced initiatives, and digital tools (e.g., ScarPath, smartphone apps, and AI-based assessments) are transforming scar research and management by centering patient priorities. Patient-powered approaches—through digital tools, crowdsourcing, and participatory research—are reshaping scar care by promoting real-world engagement and more meaningful, personalized outcomes.</div></div>","PeriodicalId":50084,"journal":{"name":"Journal of Plastic Reconstructive and Aesthetic Surgery","volume":"112 ","pages":"Pages 86-95"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145472566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Commentary to accompany: Surgical reconstruction of severe pressure ulcers in England from 01/04/2011 to 30/09/2018: Retrospective cohort study using routinely collected data 附评论:2011年4月1日至2018年9月30日英国严重压疮手术重建:使用常规收集数据的回顾性队列研究。
IF 2.4 3区 医学 Q2 SURGERY Pub Date : 2026-01-01 DOI: 10.1016/j.bjps.2025.06.023
James Chan
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引用次数: 0
Hair follicle-inspired therapies for wound healing and scar remodelling 毛囊启发治疗伤口愈合和疤痕重塑。
IF 2.4 3区 医学 Q2 SURGERY Pub Date : 2026-01-01 DOI: 10.1016/j.bjps.2025.07.023
Min Waye Chew , Summik Limbu , Paul Kemp , Claire A. Higgins
Human skin does not regenerate after severe injuries. Instead, the wound healing process repairs the skin as quickly as possible, which can lead to the formation of scar tissue. Scar tissue has reduced function compared to healthy skin; contractures limit movement, sensation is altered, the skin is itchy, and there are no functional appendages, such as sweat glands and hair follicles. As the cellular and molecular mechanisms of scarring are becoming better understood, most therapeutic strategies focus on preventing scar formation by targeting the wound healing process. One avenue of research takes inspiration from the hair follicle, as hairy skin heals with faster wound closure and reduced scar formation compared to non-hairy skin. It is thought that the hair follicle has a contributing role in this process and hair follicles transplanted into chronic (non-closing) wounds have been shown to kick-start wound closure. In the context of scarring, hair follicles transplanted into longstanding scar tissue also lead to scar remodelling. In this review, we discuss the role of hair follicles and cells or biomaterials derived from the hair follicle in both wound healing and scar remodelling.
人的皮肤在受到严重伤害后不会再生。相反,伤口愈合过程会尽可能快地修复皮肤,这可能导致疤痕组织的形成。与健康皮肤相比,疤痕组织的功能有所降低;挛缩限制运动,感觉改变,皮肤发痒,没有功能附属物,如汗腺和毛囊。随着瘢痕形成的细胞和分子机制越来越被人们所了解,大多数治疗策略都集中在通过靶向伤口愈合过程来防止瘢痕形成。一项研究从毛囊中获得灵感,因为与无毛皮肤相比,有毛的皮肤愈合速度更快,疤痕形成也更少。人们认为毛囊在这一过程中起着重要作用,将毛囊移植到慢性(非闭合)伤口中已被证明可以启动伤口愈合。在形成疤痕的情况下,将毛囊移植到长期存在的疤痕组织中也会导致疤痕重塑。在这篇综述中,我们讨论了毛囊和毛囊细胞或来源于毛囊的生物材料在伤口愈合和疤痕重塑中的作用。
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引用次数: 0
Surgical reconstruction of severe pressure ulcers in England from 01/04/2011 to 30/09/2018: Retrospective cohort study using routinely collected data 2011年4月1日至2018年9月30日英国严重压疮手术重建:使用常规收集数据的回顾性队列研究
IF 2.4 3区 医学 Q2 SURGERY Pub Date : 2026-01-01 DOI: 10.1016/j.bjps.2025.06.012
Barnaby C. Reeves , Jessica M. Harris , Maria Pufulete , Jo C. Dumville , Una Adderley , Ross Atkinson , Madeleine Clout , Nicky Cullum , Abby O’Connell , Stephen Palmer , Jeremy Rodrigues , Jason KF. Wong

Introduction

We identified patients in England admitted to hospital with severe pressure ulcers (SPUs), quantified how many had surgical reconstruction (SR) to close SPUs and described their outcomes.

Methods

Using Hospital Episode Statistics (2010ꟷ2019), we identified adults with SPU who had undergone SR. Outcomes were: length of stay; time-to-next-admission with SPU diagnosis; repeat SR; death from any cause (Office for National Statistics). Maximum and minimum numbers of SRs to close SPUs (the latter comprising a subset about whom we had greatest confidence) were estimated by applying increasingly specific filters.

Results

A minimum of 404 and maximum of 1018 patients with SPUs had SR over 7.5 years. Patients in the minimum subset were younger than the entire SR group (median 52 versus 58 years), had fewer comorbidities and were more likely to have a cause of impaired mobility. In the subset and entire group, median hospital stays after SR were 26 (IQR 13ꟷ48) and 42 (IQR 17ꟷ90) days. By one year, more patients in the subset had a further admission with SPU (24.4%, 95% CI 20.5%ꟷ29.0% versus 21.7%, 95%CI 19.2%ꟷ24.5% vs) and fewer had died (4.0%, 95%CI 2.5%ꟷ6.4% versus 14.6%, 95%CI 12.6%ꟷ16.7%); by two years, more had a second SR (10.7%, 95%CI 7.8%ꟷ14.5% versus 7.4%, 95%CI 5.7%ꟷ9.5%). Half the entire number of SRs (505/1018) were performed by 10 of 124 English hospitals.

Conclusion

Patients in the subset most likely had SR to close their SPUs. Their outcomes provide evidence that SR to close an SPU is effective for such patients.
我们确定了在英国因严重压疮(spu)入院的患者,量化了有多少人接受了手术重建(SR)来关闭spu,并描述了他们的结果。方法:使用医院事件统计(2010ꟷ2019),我们确定了接受sr治疗的SPU成人。结果是:住院时间;SPU诊断的下一次入院时间;老重复;任何原因造成的死亡(国家统计局)。通过应用越来越具体的过滤器来估计关闭spu(后者包括我们最有信心的子集)的sr的最大和最小数量。结果:最少404例,最多1018例spu患者的SR超过7.5年。最小亚组的患者比整个SR组更年轻(中位年龄为52岁对58岁),合并症更少,更有可能有活动能力受损的原因。在亚组和整个组中,SR后的中位住院时间分别为26天(IQR 13ꟷ48)和42天(IQR 17ꟷ90)。一年后,该亚群中更多的患者进一步入院SPU (24.4%, 95%CI 20.5%ꟷ29.0%对21.7%,95%CI 19.2%ꟷ24.5%对),死亡人数减少(4.0%,95%CI 2.5%ꟷ6.4%对14.6%,95%CI 12.6%ꟷ16.7%);两年后,更多的人有第二次SR (10.7%, 95%CI 7.8%ꟷ14.5%对7.4%,95%CI 5.7%ꟷ9.5%)。在124家英国医院中,有10家医院实施了全部SRs的一半(505/1018)。结论:该亚组患者最有可能通过SR关闭spu。他们的结果证明,SR关闭SPU对这类患者是有效的。
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引用次数: 0
期刊
Journal of Plastic Reconstructive and Aesthetic Surgery
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