A Case of Metastatic Synovial Sarcoma of the Lung With Recurrent Spontaneous Pneumothorax

IF 1.9 Q4 ONCOLOGY Cancer reports Pub Date : 2025-02-02 DOI:10.1002/cnr2.70104
Xunlai Lu, Shengfu Liu, Luyao Ma, Junwei Zhu, Wei Cao
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Abstract

Background

Synovial sarcoma, a highly aggressive soft tissue sarcoma, is mostly seen among young people and tends to occur in the extremities. It most commonly metastasizes to the lungs, and symptoms such as chest tightness, shortness of breath, and coughing are common after metastasis. However, multiple spontaneous pneumothorax is relatively rare. This article aims to further enhance the understanding of synovial sarcoma by introducing a case of pulmonary metastasis after surgery for synovial sarcoma originating from the sole of the foot and reviewing relevant literature.

Case

The Cardiothoracic Surgery Department of the Northeast Yunnan Central Hospital Region admitted a 40-year-old male patient. He had previously undergone surgery for synovial sarcoma on the left foot dorsum. Seven years after the surgery, the patient experienced two spontaneous pneumothorax events. A chest CT scan revealed solid nodules in the upper lobe of the left lung. Our department performed surgical removal, and pathology confirmed metastatic pulmonary synovial sarcoma. After the surgery, the patient's symptoms improved significantly, and there were no further pneumothorax attacks. The patient was then transferred to the oncology department for further treatment to improve prognosis.

Conclusion

Pulmonary metastasis of synovial sarcoma is not uncommon, and a considerable number of patients are found to have no surgical opportunity when diagnosed. In this case, the patient presented with a single solid nodule, and we adopted surgery as the first-line treatment, combined with a comprehensive treatment plan of postoperative chemotherapy to further improve the patient's prognosis.

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肺转移性滑膜肉瘤合并复发性自发性气胸1例。
背景:滑膜肉瘤是一种高度侵袭性的软组织肉瘤,多见于年轻人,易发生于四肢。它最常转移到肺部,转移后常出现胸闷、呼吸短促和咳嗽等症状。然而,多发自发性气胸相对罕见。本文通过介绍一例起源于足底的滑膜肉瘤术后肺转移的病例,并对相关文献进行复习,以进一步提高对滑膜肉瘤的认识。病例:滇东北中心医院心胸外科收治一名40岁男性患者。他曾因左脚背滑膜肉瘤接受过手术。手术后7年,患者经历了两次自发性气胸事件。胸部CT扫描显示左肺上叶实性结节。我科进行手术切除,病理证实转移性肺滑膜肉瘤。术后患者症状明显改善,无气胸再次发作。随后患者转肿瘤科进一步治疗以改善预后。结论:滑膜肉瘤肺转移并不少见,相当多的患者确诊时已无手术机会。本例患者为单一实性结节,我们采用手术作为一线治疗,结合术后化疗综合治疗方案,进一步改善患者预后。
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来源期刊
Cancer reports
Cancer reports Medicine-Oncology
CiteScore
2.70
自引率
5.90%
发文量
160
审稿时长
17 weeks
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